Last updated: February 21, 2026
What Is NDC 72205-0202?
The National Drug Code (NDC) 72205-0202 refers to a specific pharmaceutical product. According to the FDA’s database, this NDC corresponds to Ticagrelor, an antiplatelet agent used primarily in preventing thrombotic cardiovascular events in patients with acute coronary syndrome (ACS). The drug is marketed under the brand name Brilinta by AstraZeneca.
Market Overview
Current Market Size and Trends
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Global Market Value: The anti-platelet drugs segment, including Ticagrelor, was valued at approximately $4.8 billion in 2022, with a compound annual growth rate (CAGR) of around 6% (Research and Markets, 2022).
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US Market Share: The US accounts for about 45% of the global anti-platelet market, translating to roughly $2.16 billion in 2022.
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Therapeutic Adoption: Increasing incidence of ACS and PCI (percutaneous coronary interventions) sustains high demand. Ticagrelor's market penetration is high due to its superior efficacy over clopidogrel in certain patient populations, as per the PLATO trial outcomes (Wallentin et al., 2010).
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Competitive Landscape: Key competitors include Clopidogrel (Plavix), Prasugrel (Effient), and newer agents under development.
Patent Status and Market Entry
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Patent Expiration: AstraZeneca’s patent for Ticagrelor expired in 2022 in the US, opening avenues for generic manufacturers to enter the market.
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Generic Entry: Multiple generics have launched since patent expiry, increasing market competition and driving down prices.
Price Analysis
Historical and Current Pricing
| Year |
Brand Name (Brilinta) |
Average Wholesale Price (AWP) per 90 mg tablet |
Generic (per 90 mg tablet) |
| 2020 |
Brilinta |
$12.50 |
N/A |
| 2022 |
Brilinta |
$15.00 |
N/A |
| 2023 |
Brilinta |
$14.75 |
~$10.00 |
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Brand Price Trends: Slight increases in brand pricing prior to patent expiry, driven by market exclusivity.
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Post-Patent Generic Pricing: Generics launched at approximately 30-50% lower than branded prices, with prices stabilizing at around $10 per 90 mg tablet.
Future Price Projections
Revenue Potential
| Scenario |
Sales Volume (Quarterly) |
Average Price (per 90 mg tablet) |
Estimated Revenue (Quarterly) |
| Optimistic (brand dominance) |
50 million tablets |
$14.75 |
~$737.5 million |
| Conservative (generic penetration) |
70 million tablets |
$9.50 |
~$665 million |
Regulatory and Market Risks
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Patent Litigation: Ongoing patent disputes may influence the timing and scale of generic entry.
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Reimbursement Policies: Shifts towards value-based pricing and stricter formulary controls could impact sales volume and price.
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Clinical Guidelines: Emerging evidence may expand indications or alter standard-of-care practices, influencing demand.
Market Forecast Summary
| Timeline |
Market Size (US, 2022 USD) |
Price Range (per 90 mg tablet) |
Key Factors |
| 2023 |
$2.2 billion |
$10-$15 |
Post-patent generic entries, pricing competition |
| 2024 |
$2.4 billion |
$9-$14 |
Increased generics market share, new clinical data |
| 2025 |
$2.5 billion |
$8-$13 |
Stabilization of generic pricing, expanded indications |
Key Takeaways
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NDC 72205-0202 (Ticagrelor) transitioned to a highly competitive market following patent expiry in 2022.
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The US anti-platelet market is projected to grow modestly over the next three years, driven by ACS prevalence.
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Prices for generics are stabilizing around $8-$10 per 90 mg tablet, with branded prices around $14-$15.
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Revenues are expected to decrease slightly in the near term due to price competition but remain substantial owing to high demand.
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Market dynamics are sensitive to patent litigation, regulatory changes, and shifts in clinical practice.
Frequently Asked Questions
1. When did the patent for Ticagrelor (Brilinta) expire in the US?
The patent expired in August 2022, enabling generic competition.
2. How does the price of generics compare to branded Ticagrelor?
Generics typically sell at roughly 30-50% lower prices, around $8-$10 per 90 mg tablet, compared to $14-$15 for branded versions.
3. Which factors influence future price declines?
Increasing generic market share, manufacturing efficiencies, and policy changes tend to lower prices over time.
4. Are there any biosimilar or alternative treatments in development?
No biosimilar versions are in late-stage development; however, new antiplatelet agents are under clinical evaluation.
5. How does market competition influence reimbursement policies?
Payers tend to favor lower-cost generics, leading to tighter formulary restrictions on branded drugs and influencing net revenue.
References
[1] Research and Markets. (2022). Anti-Platelet Drugs Market Report.
[2] Wallentin, L., et al. (2010). Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes. The New England Journal of Medicine, 363(20), 1949-1960.
[3] FDA Database. (2023). National Drug Code Directory.
