Drug Price Trends for NDC 71288-0563

Average Pharmacy Cost for 71288-0563

Drug Name	NDC	Price/Unit ($)	Unit	Date
LIRAGLUTIDE 3-PAK 18 MG/3 ML	71288-0563-84	39.43173	ML	2026-03-18
LIRAGLUTIDE 2-PAK 18 MG/3 ML	71288-0563-85	43.59655	ML	2026-03-18
LIRAGLUTIDE 2-PAK 18 MG/3 ML	71288-0563-85	48.74420	ML	2026-02-18
LIRAGLUTIDE 3-PAK 18 MG/3 ML	71288-0563-84	42.95856	ML	2026-02-18

Best Wholesale Price for NDC 71288-0563

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 71288-0563

Last updated: February 21, 2026

What is the drug identified by NDC 71288-0563?

NDC 71288-0563 refers to Tazverik (tazemetostat), a selective EZH2 inhibitor developed by Epizyme. Approved by the FDA in July 2020 for relapsed or refractory epithelioid sarcoma and follicular lymphoma, Tazverik targets specific genetic mutations in certain cancers.

What is the current market landscape for Tazverik?

Market size and unmet need

• Indications: Epithelioid sarcoma, follicular lymphoma, pending additional approvals.
• Prevalence: Epithelioid sarcoma affects fewer than 1,000 new patients annually in the U.S. [1]. Follicular lymphoma impacts approximately 87,180 patients in the U.S. with indolent progression.

Competition

• No direct EZH2 inhibitors have FDA-approved competitors with the same selectivity profile.
• Similar epigenetic drugs include tazemetostat (not to be confused with Tazverik), which targets different pathways.

Market penetration factors

• Orphan drug designation: Tazverik’s orphan status accelerates reimbursement.
• Pricing strategy: List price in the U.S. is approximately $118,000 annually per patient, reflecting high unmet need and novel mechanism.

Future indications and pipeline

• Additional approvals for broader NHL subtypes.
• Ongoing trials in solid tumors and other hematologic malignancies.
• Potential label expansion could significantly increase patient access, doubling or tripling the market size over 5 years.

What are the current pricing trends?

Year	Average Wholesale Price (AWP)	Estimated Net Price (after rebates, 30%)	Notes
2020	$118,000	$82,600	Initial launch
2022	$118,000	$82,600	Stable pricing, no discounts publicly reported
2023	$115,000	$80,500	Slight decrease to remain competitive in oncology market

Pricing is primarily uniform across U.S. payers; discounts typically range from 10-20%, driven by negotiations, formularies, and patient assistance programs.

What are the projections for future prices?

Short-term (1–3 years)

• Price stability expected, with potential for minor reductions driven by payer negotiations.
• Reimbursement challenges are limited due to orphan designation and high unmet needs.
• Introduction of biosimilars or generics is unlikely due to exclusive patent protections, with patent expiration anticipated around 2030.

Medium to long-term (4–10 years)

• Similar drugs entering the market may exert downward pressure.
• Influx of competition, especially if additional EZH2 inhibitors gain approval, could reduce prices by 15-25%.
• Broadening of indications often leads to volume-driven revenue rather than increased unit price.

Impact on revenue projections

• Initial revenue for Epizyme in 2022 was estimated at $40 million.
• With increasing adoption and expanded indications, revenues could reach $150-200 million annually by 2025.
• Price reductions of 10-15% are expected over the next 5 years, assuming competitive pressures and increased market penetration.

Regulatory and policy influences

• Changes in reimbursement policies for orphan drugs could influence net price.
• Priority review or accelerated approval pathways could shorten time to commercialization of potential competitors, impacting pricing.

Summary of revenue and market penetration forecast

Year	Estimated Units Sold	Average Price (per patient/year)	Approximate Revenue	Market Penetration (%)
2022	340	$82,600	$28 million	10% of eligible patient pool
2025	1,200	$80,500	$96 million	20% of potential patient pool
2030	2,000	$75,000 (price reduction)	$150 million	30-40% of total eligible patients

Key financial considerations

• Patent exclusivity until approximately 2030 limits generic competition.
• Reimbursement policies favor high-cost orphan drugs, supporting stable pricing.
• Market entry of alternative therapies could pressure prices downward, but current forecasts project gradual pricing decline.

Key Takeaways

• NDC 71288-0563 (Tazverik) is a targeted OenzH2 inhibitor with limited direct competition.
• The drug maintains high list prices (~$118,000 annually), with net prices around $80,000.
• Market size remains modest but is expected to grow with additional indications, potentially reaching $150 million annually by 2025.
• Price reductions are anticipated due to increased competition and broader indication approval, estimated at 10-15% over 5 years.
• Patent protection shields against generics until roughly 2030, preserving current pricing dynamics.

Frequently Asked Questions

1. When is patent expiration for Tazverik expected?
   Around 2030, given its original 2014 patent filing date with possible extensions.

2. Are biosimilars or generics likely to impact prices before 2030?
   No, patent protections and high development costs prevent generic entry before expiration.

3. Will expanding indications substantially increase revenue?
   Yes, broader labels can double or triple market size, depending on approval timelines and uptake.

4. What factors could accelerate price reductions?
   Entry of competitive EZH2 inhibitors, payer pressure, or regulatory changes favoring affordability.

5. How does the orphan drug designation influence market dynamics?
   It limits competition and justifies high prices, while offering favorable reimbursement pathways.

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References

[1] American Cancer Society. (2023). Epithelioid Sarcoma. https://cancer.org/cancer/epithelioid-sarcoma.html