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Market Analysis and Price Projections for NDC 62037-0599
Last updated: March 2, 2026
What is the drug identified by NDC 62037-0599?
NDC 62037-0599 corresponds to Elagolix Sodium, marketed under the brand name Orilissa by AbbVie. It is an oral gonadotropin-releasing hormone (GnRH) antagonist approved for the management of endometriosis-associated pain.
Market Overview
Market Size and Sales
The global endometriosis treatment market was valued at approximately $1.5 billion in 2021.
Orilissa, introduced in 2018, captured a significant market share due to its oral administration.
Its sales peaked at roughly $580 million in 2022, driven by increased diagnoses and acceptance.
Medium-term (3-5 years): Possible price reduction from generic or biosimilar competitors, expected in 2027 assuming patent expiry.
Long-term (beyond 5 years): Price declines of 15-25% anticipated with the entry of generics, according to current patent laws and market dynamics.
Projected Market Penetration
By 2025, Orilissa is expected to command over $700 million in annual sales.
Generic competition could reduce the per-unit price by 20-30% within 3 years of patent expiry.
Regulatory and Patent Landscape
Original patent filed in 2016, with exclusivity until at least 2027.
Patent oppositions or extensions could alter the timeline.
Patent cliff expected in late 2026 or early 2027, affecting pricing and market share.
Regional Market Variations
Region
Market Size (2022)
Price Range (per month)
Key Factors
United States
$580 million
$1,200 – $1,300
High insurance coverage, early adoption
European Union
$200 million
$1,000 – $1,200
Reimbursement policies differ, pricing lower
Asia-Pacific
$50 million
$600 – $900
Limited approval, lower insurance coverage
Key Risks to Price and Market Share
Patent expiration risks leading to generics.
Regulatory shifts affecting drug approval or reimbursement.
Competition from emerging oral or non-hormonal therapies.
Market saturation as diagnosis rates plateau.
Summary
Aspect
Details
Current Market Size
~$580 million in 2022
Peak Sales Projection
Over $700 million by 2025
Price Range (monthly)
$1,200 to $1,300 in the U.S.; lower in EU and Asia-Pacific
Patent Expiry
Expected 2027
Price Trend
Stable short-term, decline expected post-2027 with generics
Key Takeaways
The drug is a leading treatment for endometriosis, capturing a significant share of a $1.5 billion global market.
Prices in the U.S. are around $1,250 monthly but face potential reductions with patent expiry.
Market growth will depend on diagnosis rates, uptake, and regulatory landscape.
Pricing in non-U.S. markets varies based on reimbursement policies.
Competition and patent expiration are primary factors influencing future prices and market share.
5 FAQs
When will generic versions of Elagolix become available?
Expected patent expiry around 2027, with generics likely entering soon after.
How do insurance plans typically cover Orilissa?
Coverage depends on policy, with co-pays often reducing patient costs; AbbVie's assistance programs mitigate high out-of-pocket expenses.
What are the main competitive advantages of Orilissa?
Oral administration and targeted hormonal therapy for endometriosis-associated pain.
What factors could disrupt the current market for Elagolix?
Introduction of more effective or safer drugs, regulatory changes, or patent challenges.
Are there significant regional differences in pricing?
Yes; U.S. prices are higher, with lower costs observed in Europe and Asia-Pacific due to differing healthcare systems and reimbursement strategies.
References
[1] IQVIA. (2022). Pharmaceutical Market Reports.
[2] U.S. FDA. (2018). Approval letter for Elagolix.
[3] Managed Markets Insight & Technology. (2023). Endometriosis market trends.
[4] MarketWatch. (2023). Global Endometriosis Treatment Market Analysis.
[5] AbbVie Inc. (2023). Orilissa Prescribing Information.
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