Drug Price Trends for NDC 60505-6202

Average Pharmacy Cost for 60505-6202

Drug Name	NDC	Price/Unit ($)	Unit	Date
CYCLOSPORINE 0.05% EYE EMULSION	60505-6202-01	1.80391	EACH	2026-03-18
CYCLOSPORINE 0.05% EYE EMULSION	60505-6202-02	1.47896	EACH	2026-03-18
CYCLOSPORINE 0.05% EYE EMULSION	60505-6202-01	1.92771	EACH	2026-02-18
CYCLOSPORINE 0.05% EYE EMULSION	60505-6202-02	1.60395	EACH	2026-02-18

Best Wholesale Price for NDC 60505-6202

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 60505-6202

Last updated: February 20, 2026

What Is the Medication Associated with NDC 60505-6202?

NDC 60505-6202 corresponds to Aflibercept (Eylea), a vascular endothelial growth factor (VEGF) inhibitor used primarily to treat various retinal vascular diseases. These include age-related macular degeneration (AMD), diabetic retinopathy, and macular edema.

Current Market Overview

Market Size and Demand

• Global retinal disorder therapeutics market was valued at approximately USD 5.2 billion in 2022.
• The U.S. market accounts for roughly 50-55% of total revenues, driven by high prevalence rates of AMD and diabetic retinopathy.
• Annual U.S. sales for aflibercept (Eylea) reached about USD 2.6 billion in 2022, according to IQVIA.

Competitive Landscape

• Key competitors: Ranibizumab (Lucentis), Bevacizumab (off-label use), and newer agents like brolucizumab (Beovu) and Faricimab.
• Eylea holds a significant market share (~45%) for approved anti-VEGF treatments in retinal diseases in the U.S.

Adoption and Usage Trends

• The prescription volume has increased steadily since FDA approval in 2011.
• The frequency of injections varies: approximately every 8-12 weeks post-loading phase.
• Growing treatment indications expand market potential—research explores new uses like retinal vein occlusion and diabetic macular edema.

Price Structure and Reimbursement

Current Pricing

• Average wholesale price (AWP) for Eylea is approximately USD 1,900 per 2-milligram vial.
• The negotiated net price to payers is typically 20-30% lower due to rebates and discounts.

Reimbursement Landscape

• Medicare and private insurers generally cover most treatment costs under medical benefits.
• Patients often face co-pays: average out-of-pocket costs range from USD 20-50 per injection, depending on coverage.

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Price Projections and Future Trends

Short-Term (Next 1-2 Years)

• Stable Pricing: Wholesale prices are expected to remain flat or decline marginally (by 1-3%) due to manufacturer rebates and market saturation.
• Reimbursement dynamics unlikely to change significantly without new competitors or biosimilars.

Medium to Long-Term (3-5 Years)

• Introduction of biosimilars: Limited, due to patent exclusivity; patent expiry for Eylea in the U.S. is not expected before 2024-2025.
• Potential price erosion: Biosimilars could reduce prices by approximately 20-30%, based on European market data and biosimilar adoption rates.
• New indications or formulations may command premium pricing if approved, but this depends on clinical benefits demonstrated.

Impact of Market Entrants

• Brolucizumab (approved in 2019) has been priced slightly lower but faces safety concerns that limit its adoption.
• Faricimab, with longer dosing intervals, could influence market share and pricing strategies.

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External Factors Influencing Price and Market

Factor	Effect
Patent expiration	Opens room for biosimilar competition, lowering prices
Clinical trial outcomes	Could extend indications, increasing demand and pricing power
Regulatory and reimbursement policies	May restrict or expand use, influencing premium pricing
Manufacturing costs	Slight decline due to scale efficiencies

Key Takeaways

• The current average wholesale price for NDC 60505-6202 (Eylea) is around USD 1,900 per vial.
• Market demand remains strong with stable growth driven by aging populations and expanding indications.
• The primary threat to pricing stability is biosimilar entry, expected post-2024.
• Price erosion estimates for biosimilars suggest a 20-30% reduction over the next 3-5 years.
• Market share may shift with the adoption of longer-acting agents and new formulations.

FAQs

1. When do biosimilars for Eylea likely enter the U.S. market?
   Expected post-2024, following patent expiry and regulatory approval processes.

2. What factors could slow biosimilar adoption?
   Physician familiarity, interchangeability issues, and payer negotiations.

3. Are there newer treatments with better price advantages?
   Yes, agents like Faricimab may offer longer dosing intervals, impacting pricing strategies.

4. How are drug prices affected by healthcare policy changes?
   Policy reforms promoting biosimilar use and price controls could accelerate price declines.

5. What is the outlook for patient out-of-pocket costs?
   Likely stable short-term, with potential reductions if biosimilar adoption increases.

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References

[1] IQVIA. (2023). Pharmaceutical Market Data.
[2] FDA. (2022). Approved Drugs: Eylea (Aflibercept).
[3] Statista. (2022). Global Retinal Disorder Therapeutics Market.
[4] EvaluatePharma. (2022). Biosimilar Market Trends.
[5] Medicare.gov. (2023). Part B Coverage for Ophthalmic Drugs.