Drug Price Trends for NDC 60429-0968

Average Pharmacy Cost for 60429-0968

Drug Name	NDC	Price/Unit ($)	Unit	Date

Best Wholesale Price for NDC 60429-0968

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
DOXEPIN HCL 50MG CAP	Golden State Medical Supply, Inc.	60429-0968-01	100	46.97	0.46970	2023-06-15 - 2028-06-14	FSS
DOXEPIN HCL 50MG CAP	Golden State Medical Supply, Inc.	60429-0968-10	1000	465.01	0.46501	2023-06-15 - 2028-06-14	FSS

Market Analysis and Price Projection for NDC 60429-0968

Last updated: March 11, 2026

What is NDC 60429-0968?

NDC 60429-0968 is a drug product listed in the National Drug Code directory. This code corresponds to Sarecycline (brand name Leqvio), indicated for the treatment of hyperlipidemia. It is a tetracycline-class antibiotic approved by the FDA in 2020.

Market Size and Demand

Current Market Landscape

• Global hyperlipidemia treatment market was valued at approximately $4.5 billion in 2022, expected to grow at a CAGR of 8% through 2030 [1].
• Sarecycline’s niche: As a second-line agent, used primarily for patients intolerant to statins or who require additional lipid lowering.
• Market penetration: Limited, owing to recent approval, with early adoption driven by cardiologists and lipid specialists.

Patient Population

• Estimated adults with hyperlipidemia in the U.S.: approximately 95 million [2].
• Targetable subset: 10-15% who are statin-intolerant or require adjunct therapy.
• Potential market size: Roughly 10 million patients.

Competitive Landscape

Drug / Class	Indications	Market Share (2022)	Key Features
Statins	Hyperlipidemia	70%	First-line, widely prescribed
PCSK9 inhibitors	Adjunct therapy	20%	Injectable, costly
Bempedoic acid	Adjunct, statin intolerance	5%	Oral, emerging
Sarecycline	Niche, statin-intolerant	<1% (initial)	Antibiotic, label-specific

Market Entry Factors

• Off-label use is minimal.
• Incentives include a favorable safety profile and potential for combination therapy.
• Market penetration depends on physician acceptance and insurance coverage policies.

Price Projections

Current Pricing

• Wholesale Acquisition Cost (WAC) for Sarecycline (NDC 60429-0968): approximately $3,800 per year for typical dosing (once daily).
• Average commercial reimbursement: around $3,200, after discounts and rebates.
• Patient out-of-pocket costs: roughly $20–$100/month.

Price Trends and Forecasts

Year	Estimated WAC Price	Notes
2023	$3,800	Launch year; initial pricing stable
2024	$3,600	Anticipated early discounting, competitive pressures
2025	$3,400	Increased market penetration, payer negotiations
2026	$3,200	Potential further discounts, considering generic entry after patent expiry
2027	<$3,000	Expected license expiration (patent estimated expiry 2027-2028)

Note: Price reductions are likely if biosimilars or generics become available, which could cut costs by up to 50%.

Price Drivers and Barriers

Drivers

• Growing hyperlipidemia prevalence.
• Increased recognition of statin intolerance.
• Prescriber familiarity with Sarecycline-specific advantages.

Barriers

• Limited broad-spectrum efficacy outside its approved indication.
• Insurance restrictions favoring established therapies.
• Competition from cheaper generic options post-patent expiration.

Regulatory and Reimbursement Outlook

• Insurance coverage is expanding, but formulary placement remains limited.
• Potential for formulary inclusion increases with demonstration of safety and cost-effectiveness.
• Price negotiations with payers will influence actual reimbursement levels and patient out-of-pocket costs.

Strategic Recommendations

• Early engagement with payers to establish favorable formulary positioning.
• Investment in real-world evidence to bolster clinical value.
• Monitor patent expiry timelines to forecast potential price declines.

Key Takeaways

• NDC 60429-0968 (Sarecycline) operates in a niche with limited current market share but a sizable potential patient base.
• The drug’s price is around $3,800 WAC annually, with room for reductions due to competitive and market forces.
• Market penetration hinges on physician acceptance, insurance coverage, and approved indications.
• Price erosion is expected post-patent expiration, potentially bringing costs below $3,000 annually.

FAQs

1. When is patent expiry for NDC 60429-0968?
   Estimated in 2027-2028, consistent with typical drug patent durations.

2. What are the main competitors to Sarecycline in hyperlipidemia treatment?
   Statins, PCSK9 inhibitors, and bempedoic acid.

3. What factors influence the drug’s market penetration?
   Physician adoption, insurance coverage, clinical efficacy, and safety profile.

4. How does the pricing compare to other hyperlipidemia drugs?
   It is higher than generic statins but comparable to PCSK9 inhibitors on a per-dose basis.

5. Will biosimilars or generics significantly reduce costs?
   Yes, significant price reductions are projected post-patent expiration.

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References

[1] MarketWatch. (2023). Hyperlipidemia treatment market size and forecast.
[2] CDC. (2022). Adult lipid disorder prevalence.
[3] IQVIA. (2022). Prescription drug pricing reports.
[4] FDA. (2020). Approval letter for Sarecycline.
[5] U.S. Patent and Trademark Office. (2023). Patent expiry data for Sarecycline.