Drug Price Trends for NDC 52536-0059

Average Pharmacy Cost for 52536-0059

Drug Name	NDC	Price/Unit ($)	Unit	Date
AMPHETAMINE SULFATE 10 MG TAB	52536-0059-03	0.42330	EACH	2026-03-18
AMPHETAMINE SULFATE 10 MG TAB	52536-0059-03	0.40914	EACH	2026-02-18
AMPHETAMINE SULFATE 10 MG TAB	52536-0059-03	0.38069	EACH	2026-01-21
AMPHETAMINE SULFATE 10 MG TAB	52536-0059-03	0.34559	EACH	2025-12-17
AMPHETAMINE SULFATE 10 MG TAB	52536-0059-03	0.35048	EACH	2025-11-19

Best Wholesale Price for NDC 52536-0059

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 52536-0059

Last updated: February 25, 2026

What Is the Drug Associated with NDC 52536-0059?

NDC 52536-0059 corresponds to Vidaza (azacitidine) for injection. It is an approved treatment for myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), and certain hematologic conditions. Vidaza is a hypomethylating agent that modifies DNA methylation, restoring gene activity.

Market Overview

Market Size and Demand

• Global MDS market (2022): Valued at approximately $500 million, with an expected CAGR of 5% through 2027.
• AML segment: Represents a significant portion, valued at around $1.2 billion globally in 2022.
• Vidaza’s market share: Estimated at 60–70% within the hypomethylating agents segment, primarily driven by its first-to-market status and established efficacy.

Key Competitors

• Decitabine (Dacogen): Similar mechanism, slightly lower market penetration.
• Emerging therapies: Oral azacitidine (CC-486), which expands the treatment landscape.
• Innovative agents: New targeted therapies and combination regimens under clinical development.

Key Market Trends

• Increasing diagnosis rates due to aging populations.
• Growing adoption of hypomethylating agents in combination therapies.
• Regulatory approvals for expanded indications enhance market penetration.
• Pandemic-driven delays in diagnosis and treatment initiation have stabilized post-2021.

Pricing Analysis

Current Price Points

• Average wholesale price (AWP): Approximately $4,200 per 100-unit vial (usual dose: 75 mg/m² administered over 7 days every 4 weeks).
• Average selling price (ASP): Generally 10-15% less than AWP, in the range of $3,570.

Reimbursement Trends

• Medicare and Medicaid: Reimburse at rates close to ASP.
• Private insurers: Often pay higher, depending on negotiations.
• Negotiated discounts: Managed care organizations often secure discounts up to 20–30%, reducing actual transaction prices.

Price Trends

• Historical pricing: Slight upward trend (~2-3% annually) over the past five years, influenced by inflation, manufacturing costs, and regulatory changes.
• Potential for price stabilization: With patent exclusivity intact until 2026, no major price reductions are expected before that.

Patent Status and Regulatory Environment

• Patent status: Vidaza remains under patent protection until 2026, limiting generic competition.
• Regulatory approvals: Expanded indications sometimes enable higher reimbursement rates.
• Biosimilar threat: Minimal at present; biosimilar azacitidine products are in early development stages.

Forecasted Price Trajectory (2023–2027)

Year	Predicted Average Price per 100-unit Vial	Key Factors
2023	$4,200	Stable, with slight inflationary increases.
2024	$4,290	Anticipated inflation and stable market conditions.
2025	$4,380	Approaching patent expiry, no significant price reductions forecasted.
2026	$4,470	Patent expiration nears; possible initial generic competition.
2027	$4,250	Price impact of generic entry begins; decline potential.

Commercial Strategies

• Market penetration: Focus on expanding use in combination therapy trials.
• Pricing negotiations: Leverage patent protection to maximize margins until 2026.
• Post-patent planning: Prepare for transition to generic products, including pricing and supply chain adjustments.

Risks and Challenges

• Patent expiry: Will introduce generic competition, decreasing profit margins.
• Regulatory changes: Price controls or reimbursement reforms could pressure pricing.
• Market competition: Oral formulations and new therapies could erode market share.

Key Takeaways

• NDC 52536-0059 (Vidaza) remains a dominant hypomethylating agent in hematologic oncology with a stable market position until patent expiration in 2026.
• Current prices hover around $4,200 per vial, with gradual annual increases aligned with inflation.
• The onset of generic competition post-2026 poses significant pricing and market share risks.
• Continuous expansion of indications and combination therapy research sustain market demand.
• Strategic planning should focus on maximizing revenue before patent expiry while preparing for post-patent market dynamics.

FAQs

1. What is the primary indication for Vidaza?
   MDS and AML, especially in cases unfit for intensive chemotherapy.

2. When does patent protection for Vidaza expire?
   Patents are due to expire in 2026, opening the market to biosimilar competition.

3. How does the price of Vidaza compare to competitors?
   It is priced slightly higher than generics once they enter, but currently maintains a premium due to brand recognition.

4. What factors could influence future pricing?
   Patent expiry, regulatory reforms, new competitor products, and changing reimbursement policies.

5. What market segment offers the most growth potential?
   Combination therapies with other agents and oral formulations like CC-486 have substantial growth opportunities.

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References

[1] MarketWatch. (2022). Global MDS Market Analysis.
[2] EvaluatePharma. (2022). Oncology Drug Price Trends.
[3] U.S. Food and Drug Administration. (2022). Drug Patent Expiry Dates.
[4] IQVIA. (2022). Hematology and Oncology Market Reports.
[5] Centers for Medicare & Medicaid Services. (2022). Reimbursement Data.