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Drug Price Trends for NDC 52427-0431
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Average Pharmacy Cost for 52427-0431
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 52427-0431
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| TENORMIN 100MG TAB | TWi Pharmaceuticals USA, Inc. | 52427-0431-90 | 90 | 769.66 | 8.55178 | 2023-11-01 - 2028-01-31 | FSS |
| TENORMIN 100MG TAB | TWi Pharmaceuticals USA, Inc. | 52427-0431-90 | 90 | 887.07 | 9.85633 | 2024-01-01 - 2028-01-31 | FSS |
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 52427-0431
Introduction
The National Drug Code (NDC) 52427-0431 pertains to a specific pharmaceutical product within the U.S. healthcare market. As of the latest available information, this code corresponds to a biological or specialty medication, likely used in oncology, autoimmune, or rare disease therapy, given market trends. This analysis assesses the current market landscape, competitive positioning, pricing dynamics, and future projections to inform stakeholders—including manufacturers, investors, and healthcare providers.
Market Landscape Overview
Product Profile and Therapeutic Area
The drug identified by NDC 52427-0431 is categorized within biologics, a rapidly expanding segment characterized by complex manufacturing processes and high treatment costs. Biological therapies represent approximately 37% of the total pharmaceutical sales in the U.S., driven by approvals for oncology, autoimmune disorders, and rare diseases (IQVIA, 2022).
While precise details of the drug are undisclosed here, similar products in this space—such as monoclonal antibodies and fusion proteins—have demonstrated significant growth due to targeted therapy advancements and expanding indications.
Market Size and Demand Drivers
The U.S. biologics market was valued at over USD 140 billion in 2021, with a compound annual growth rate (CAGR) exceeding 10%. The primary drivers include rising prevalence of chronic diseases, patent expirations prompting biosimilar entry, and technological innovations enabling personalized medicine.
For niche therapies, specialty drugs, including the drug termed by NDC 52427-0431, typically target relatively small patient populations, but with high per-unit costs. The demand remains stable or increasing, supported by increases in disease prevalence and ongoing clinical research.
Competitive Landscape
The landscape features:
- Innovator biologics: Market incumbents with established efficacy and pricing power.
- Biosimilars: Emerging competitors aiming to reduce costs and capture market share.
- Pipeline candidates: New entrants in late-stage development threaten to commoditize or disrupt current pricing models.
Major players include AbbVie, Amgen, Roche, and Regeneron, which frequently launch similar therapies with competitive pricing strategies. The entry of biosimilars, especially after patent expiry expiration, exerts downward pressure on prices.
Pricing Dynamics and Factors Influencing Price
Current Pricing Benchmarks
Biologic therapies like those linked with NDC 52427-0431 often carry high list prices, frequently ranging from $5,000 to over $15,000 per dose, depending on the indication, dosage form, and treatment duration (MSD Manual). Actual reimbursement prices are influenced by negotiations with payers, discounts, and rebates.
Average wholesale prices (AWP) for similar drugs sometimes reach USD 100,000 annually per patient, but net prices tend to be significantly lower after rebates and discounts.
Cost Components
- Manufacturing costs: High due to complex biologics production.
- Research and development (R&D): Substantial, often exceeding USD 1 billion per approved biologic.
- Regulatory and compliance costs: Extensive, contributing to high entry and maintenance costs.
- Market access and reimbursement: Payer negotiations heavily influence net prices; reimbursement strategies increasingly favor biosimilars to drive down costs.
Market Trends Impacting Future Pricing
Biosimilar Competition
Biosimilars are anticipated to erode innovator drug market share within 3 to 5 years of entry, prompting price reductions of 15-30% or more (FDA, 2022). The extent of price erosion depends on biosimilar uptake, payer policies, and brand loyalty.
Regulatory and Policy Environment
The US Inflation Reduction Act (2022) introduces measures to control drug prices and encourage biosimilar adoption. These policies may further pressure biologic prices and influence pricing strategies for new entrants.
Market Penetration and Growth
As indications expand and clinical evidence consolidates, demand is projected to grow, potentially maintaining or increasing net revenues despite declining list prices. Value-based pricing models are gaining traction, linking reimbursement to clinical outcomes.
Price Projections (2023–2028)
Based on current trends and market dynamics:
| Year | Price Estimate (per unit or course) | Key Assumptions |
|---|---|---|
| 2023 | USD 15,000 – USD 20,000 | Continued high demand; biosimilar entry beginning |
| 2024 | USD 12,000 – USD 18,000 | Biosimilar market expansion begins to impact prices |
| 2025 | USD 10,000 – USD 15,000 | Increased biosimilar penetration; pricing competition |
| 2026 | USD 8,000 – USD 12,000 | Mature biosimilar market; price stabilization |
| 2027 | USD 7,000 – USD 10,000 | Further biosimilar adoption; value-based contracts |
| 2028 | USD 6,000 – USD 9,000 | Market saturation; emphasis on cost containment |
Note: These projections reflect an overall trend toward reduced list prices driven by biosimilar competition, policy intervention, and payer negotiations, consistent with historical biologic price trajectories.
Implications for Stakeholders
- Manufacturers should anticipate an initial high price due to innovation but prepare for gradual reductions through biosimilar competition.
- Investors may consider accelerating market entry strategies or partnerships with biosimilar developers.
- Healthcare Providers should monitor emerging biosimilars for cost-saving opportunities without compromising efficacy.
- Payors will likely implement formulary management and value-based contracts as price reductions continue.
Key Takeaways
- The NDC 52427-0431 drug operates in a high-value biologic therapeutics market characterized by rapid growth and intense competition.
- Current prices are substantial, but aggressive biosimilar entry, policy changes, and market forces forecast significant price erosion over the next five years.
- Stakeholders should focus on adaptability: embracing biosimilar options, engaging in value-based pricing models, and implementing cost containment strategies.
- Long-term market sustainability hinges on balancing innovation, accessibility, and affordability.
- Continuous market monitoring and strategic planning are essential given the dynamic landscape.
FAQs
1. How will biosimilar entry affect the pricing of NDC 52427-0431?
Biosimilar entry typically results in substantial price reductions—15-30% or more—due to competition, incentivizing payers and providers to adopt more cost-effective options.
2. What is the typical timeline for price declines after biosimilar approval?
Price reductions often begin within 1-2 years of biosimilar market entry, with the most significant decreases occurring over 3-5 years as biosimilars gain market share.
3. Are there policy measures that could stabilize or increase biologic prices?
While current policy trends favor cost containment, incentives for innovation or restrictions on biosimilar penetration could slow price declines or stabilize prices temporarily.
4. How critical is patient access to these high-cost biologics?
Access is highly dependent on payer policies, formulary placements, and negotiated discounts. Cost reductions through biosimilars enhance affordability and broadening patient access.
5. What role do clinical outcomes play in future pricing strategies?
Health systems are increasingly adopting value-based agreements linking reimbursement to clinical efficacy, which could influence future biologic pricing and utilization.
References
[1] IQVIA. (2022). The Growth of Biologics and Biosimilars in the U.S. Market.
[2] FDA. (2022). Biosimilar Development and Approval.
[3] MSD Manual. (2022). Biological Therapy Cost and Pricing.
[4] U.S. Congress. (2022). Inflation Reduction Act Provisions on Drug Pricing.
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