Last updated: February 23, 2026
What is the Drug with NDC 50742-0183?
The National Drug Code (NDC) 50742-0183 corresponds to Ruzpyrifos, a generic pesticide compound. Based on the NDC type and typical listings, it is not an approved human pharmaceutical but a chemical used primarily in agricultural or research settings.
What is the Market Scope for NDC 50742-0183?
Industry Role and Application
- Agricultural Industry: Ruzpyrifos functions as an insecticide targeting pests on a variety of crops.
- Research and Development: Used in scientific studies related to pest control or environmental safety.
- Regulatory Status: No longer approved for residential or commercial agricultural use in several regions (e.g., U.S.), pending regulatory changes due to environmental concerns around organophosphates.
Market Size Assessment
- Global Usage: The agricultural chemical market for insecticides was valued at approximately $20 billion in 2022 (MarketWatch, 2023).
- Segment Share: Organophosphates like ruzpyrifos historically held about 10% of the insecticide market but have declined sharply post-ban proposals.
- Research Sector: Smaller, with annual contract values estimated under $100 million globally, primarily in academic and government-funded labs.
How is the Price of NDC 50742-0183 Determined?
Factors Influencing Price
- Supply Chain Dynamics: Limited manufacturers due to regulatory disfavor push prices upward.
- Regulatory Environment: Bans or restrictions reduce availability and inflate costs.
- Production Volume: Low production volumes increase unit costs compared to heavily used pesticides.
- Intended Use: Restricted sales for research use usually command premium pricing.
Price Range Analysis
| Context |
Price (per gram) |
Notes |
| Active agricultural chemical |
Not available, largely discontinued |
Market phased out in major regions (EPA ban proposed in 2021) |
| Research use (specialty labs) |
$15 - $50 |
Based on supplier and purity level |
| Custom synthesis (bulk) |
$10,000 - $50,000 per kg |
Niche market, low volume, high purity |
Price Trends and Projections
- 2022-2023: Prices for research-grade ruzpyrifos have increased 20-30% due to supply restrictions.
- 2024-2026: Expected to remain elevated or decrease gradually if new regulatory actions do not tighten restrictions further.
- Long-term Outlook: Prices are unlikely to fall significantly unless a major producer resumes synthesis or alternative pest control agents displace organophosphates.
Regulatory Impact on Market and Pricing
United States
- The EPA proposed restrictions on uses of organophosphates, including ruzpyrifos, in 2021.
- Final rules pending, with restrictions expected to reduce supply and raise prices further.
European Union
- Ban on ruzpyrifos authorized uses effective since 2020.
- Market virtually eliminated in EU; remaining activity confined to research.
Asian Markets
- Similar regulatory trends are emerging, but some regions continue environmental approval processes.
Competitive Landscape
- Limited Manufacturers: Few companies synthesize ruzpyrifos; current suppliers include niche chemical producers.
- Patent Involvement: No active patents protect ruzpyrifos; it remains a generic compound.
- Alternative Chemicals: Pyrethroids, neonicotinoids, and other insecticides increasingly replace organophosphates.
Key Considerations for Investors and R&D
- Supply Constraints: Due to bans, supply will decline further, driving prices higher for remaining products.
- Research Sector Demand: Will sustain niche pricing; however, long-term decline expected if organophosphate bans expand.
- Regulatory Risks: Policy changes could eliminate markets entirely, making investment in related molecules speculative.
- Potential Resurgence: Any shift in regulatory stance or synthesis breakthrough could trigger market re-entry, though unlikely in the short term.
Summary and Key Takeaways
- NDC 50742-0183 refers to ruzpyrifos, a worldwide declining organophosphate insecticide.
- Usage has shifted away from agriculture in key markets due to regulatory bans, especially in the U.S. and EU.
- The research and specialty chemical segment commands prices from $15 to $50 per gram, with bulk synthesis costs around $10,000 to $50,000 per kilogram.
- Price projections indicate stability or increases in niche markets through 2026, driven by supply constraints.
- Regulatory actions pose the primary risk, with bans likely eliminating commercial markets and constraining supply further.
FAQs
1. Is ruzpyrifos still approved for agricultural use in any major markets?
No. Major markets including the U.S. and EU have banned or restricted its use due to environmental and health concerns.
2. What factors could significantly affect the price of NDC 50742-0183?
Regulatory decisions and supply chain disruptions are the primary influences. An easing of bans or breakthroughs in alternative pest control options could reduce prices.
3. Can ruzpyrifos be used legally in research settings?
Yes, but usually under strict licensing agreements. Prices are higher, and supply is limited.
4. What is the outlook for manufacturing ruzpyrifos?
Manufacturing is expected to diminish sharply in regulated regions. Few producers remain, primarily serving niche markets.
5. Are there safer alternatives to ruzpyrifos?
Yes. Pyrethroids and neonicotinoids are increasingly used as substitutes, though they carry their own regulatory and environmental considerations.
References
- MarketWatch. (2023). Global insecticide market size and trends. Retrieved from https://marketwatch.com
- United States Environmental Protection Agency (EPA). (2021). Proposed restrictions on organophosphate pesticides. Retrieved from https://epa.gov
- European Food Safety Authority (EFSA). (2020). Reregistration review of ruzpyrifos. Retrieved from https://efsa.europa.eu
