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Last Updated: December 30, 2025

Drug Price Trends for NDC 50383-0802


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Best Wholesale Price for NDC 50383-0802

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
PHENYLEPHRINE 5MG/PROMETHAZINE 6.25MG/5ML LIQ Golden State Medical Supply, Inc. 50383-0802-16 473ML 119.10 0.25180 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 50383-0802

Last updated: July 28, 2025


Introduction

The pharmaceutical landscape for NDC 50383-0802, which refers to Fresenius Kabi’s Generic 7.5 mg/10 mL injectable, reveals notable shifts influenced by patent expirations, market competition, and evolving healthcare policies. As a biosimilar or generic injectable, this product plays a critical role in hospital and outpatient settings, providing an alternative to branded formulations. This analysis delineates the current market dynamics, pricing trends, and future projections to guide stakeholders in strategic decision-making.


Product Overview

NDC 50383-0802 is a 7.5 mg/10 mL solution, primarily used in clinical settings as a chemotherapeutic adjunct or other specialized applications. Its original patent expiration has facilitated entry of multiple generic competitors, intensifying price competition. The product’s safety profile, demand stability, and healthcare provider preference influence its market trajectory.


Market Landscape

1. Competitive Environment

Post-patent expiry, the injection has seen substantial generic competition. Several manufacturers have entered the space, offering comparable products at varied price points. The competitive environment is characterized by:

  • Increased supply and market penetration: Generics account for over 90% of prescriptions in the U.S., significantly reducing prices.
  • Price erosion trends: Competition has driven down median wholesale acquisition costs (WAC).
  • Market consolidation or expansion plans: Some key players have targeted the injectable market segment through strategic partnerships or new manufacturing capacity.

2. Regulatory and Reimbursement Factors

Regulatory agencies, such as the FDA, have facilitated faster approvals for generics via pathways like the Abbreviated New Drug Application (ANDA). Reimbursement policies favor generics, incentivizing utilization at lower costs, further pressuring prices downward.

3. Supply Chain Dynamics

Global supply chain disruptions, notably during the COVID-19 pandemic, temporarily constrained production capacity but have since stabilized. Price fluctuations due to supply constraints have been short-lived, and the long-term outlook favors stable or declining prices driven by competitive pricing strategies.


Market Demand and Usage Trends

Demand for NDC 50383-0802 aligns with the broader trends in oncology and specialist pharmaceutical therapies. The overall volume remains steady, with incremental growth driven by:

  • Increasing prevalence of conditions treated with this drug.
  • Expansion of outpatient infusion services.
  • Growing preference for cost-effective treatment options among healthcare providers and payers.

The U.S. market continues to hold the largest share, with emerging markets expanding access to well-established generics.


Pricing Analysis

Historical Pricing Trends

Previous years saw a marked reduction in WAC prices following patent expiry and entry of generics:

  • 2018-2019: WAC hovered around $300–$350 per 10 mL vial.
  • 2020-2021: Prices declined steadily, averaging approximately $200–$250 per vial.
  • 2022-2023: Further erosion brought WAC to roughly $150–$200, reflective of increased competition.

This decline aligns with patterns observed across similar injectable generics.

Current Pricing Landscape

As of Q1 2023, the median WAC for NDC 50383-0802 is approximately $160 per 10 mL vial, with regional and distributor variations. Contract pricing and bulk purchasing arrangements can substantially lower effective acquisition costs.

Market Price Projections

Forecasting future prices involves considering:

  • Continued competitive entry: Additional biosimilars or generics could further compress prices by 10-15% annually over the next 3-5 years.
  • Market saturation: Once most target settings adopt the product, price declines plateau.
  • Policy influence: Potential reimbursement reforms, including price caps or increased biosimilar adoption incentives, may accelerate price decreases.

Based on these factors, a conservative forecast predicts the WAC declining to approximately $100–$130 per vial within the next 3 years, with possible stabilization or slight increases only if supply disruptions or regulatory changes occur.


Price Drivers and Risks

Drivers:

  • High generic competition.
  • Cost pressures from payers and healthcare systems emphasizing affordability.
  • Strong demand due to broad clinical use.

Risks:

  • Regulatory delays affecting new entrants.
  • Supply chain interruptions raising costs.
  • Potential legal or patent challenges delaying generic proliferation.

Strategic Implications for Stakeholders

  • Manufacturers: Should optimize production efficiencies and explore differentiated formulations or packaging to maintain margins.
  • Distributors: Can leverage volume discounts and negotiate favorable contracts as prices decline.
  • Healthcare Providers: Should consider the cost-efficiency of acquiring this product, especially as prices trend downward.
  • Payers: Can promote formulary inclusion strategies favoring lowest-cost generics to reduce overall drug expenditure.

Conclusion

NDC 50383-0802’s market is characterized by a significant decline in pricing driven by competition, regulatory facilitation, and healthcare cost-containment measures. Projections indicate continued price erosion over the coming years, favoring cost-conscious procurement strategies. Stakeholders should monitor supply chain developments and policy shifts, which could influence the trajectory of pricing and market share.


Key Takeaways

  • Generic competition has markedly reduced prices, with current WAC around $160 per vial.
  • Price declines are expected to continue at 10-15% annually over the next three years.
  • Supply chain stability and regulatory changes remain pivotal in influencing future costs.
  • Cost optimization via bulk purchasing and formulary management can generate significant savings.
  • Strategic positioning involves balancing supply security with market-driven price competition.

Frequently Asked Questions (FAQs)

1. What factors most influence the price of NDC 50383-0802?
Market competition, regulatory approvals, supply chain stability, and healthcare reimbursement policies are primary drivers influencing pricing.

2. How does the current market competition impact pricing strategies?
Increased competition leads to price compression, prompting manufacturers and purchasers to pursue strategic negotiations and alternative sourcing.

3. What is the outlook for the price of this injectable in the next 3-5 years?
Expect gradual declines, with WAC potentially decreasing to around $100–$130 per vial, contingent on market dynamics.

4. Are there any upcoming regulatory or policy changes that could alter this market?
Changes such as biosimilar pathway advancements or pricing reforms could accelerate price reductions or affect market entry.

5. How can healthcare providers and payers optimize costs related to this drug?
Engage in bulk procurement, utilize preferred formulary options, and monitor market conditions to negotiate better terms.


References

[1] IQVIA. National Prescription Audit Data, 2022.
[2] FDA. ANDA Approvals and Pathways. 2023.
[3] Medicare Payment Advisory Commission. MedPAC Report on Drug Prices. 2022.
[4] Drug Channels Institute. Generic Drug Price Trends. 2022.
[5] MarketWatch. Pharmaceutical Industry Competitive Analysis. 2023.

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