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Last Updated: January 1, 2026

Drug Price Trends for NDC 46122-0557


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Best Wholesale Price for NDC 46122-0557

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 46122-0557

Last updated: August 2, 2025

Introduction

The National Drug Code (NDC) 46122-0557 pertains to a specific pharmaceutical product, and understanding its market landscape, pricing dynamics, and future projections is crucial for stakeholders including pharmaceutical companies, healthcare providers, insurers, and investors. This analysis synthesizes current market conditions, regulatory factors, competitive landscape, and economic trends to offer comprehensive insights into this drug’s position within the pharmaceutical ecosystem.

Product Overview and Context

NDC 46122-0557 corresponds to a branded or generic formulation (specifics depend on the manufacturer and drug classification). While the exact drug details are proprietary, this analysis assumes the product operates within a competitive therapeutic category, such as oncology, neurology, or chronic disease management—common sectors for NDC codes in this format.

Given the increasing importance of market access and cost containment in healthcare, the product’s pricing strategies are influenced by regulatory pathways, patent status, and evolving treatment guidelines.

Market Landscape

1. Regulatory Status and Patent Dynamics

The regulatory environment significantly impacts the drug's marketability and price stability. If NDC 46122-0557 represents a patented biologic or innovative molecule, exclusivity periods offer substantial pricing leverage. Once patent expiration approaches, biosimilar or generic entries are likely, increasing competition and driving prices downward.

Current patent protections extend into the next several years for many innovative drugs, aligning with recent patent filings and FDA approval timelines (per [1]). If the product utilizes a novel delivery system or unique formulation, it may benefit from additional exclusivity provisions, such as data exclusivity or orphan drug status, further stabilizing prices temporarily.

2. Competitive Landscape

The competition within the therapeutic class directly influences pricing. The presence of multiple approved therapies or biosimilars can pressure prices downward. Recent market entries, especially biosimilars, have disrupted previous pricing models, creating more affordable alternatives that challenge the original drug’s market share.

Market share data from IQVIA indicate that when biosimilars enter, original biologics’ prices tend to decrease by approximately 15-30% within the first year post-generic entry (per [2]). For small-molecule generics, similar trends are observed, with price reductions averaging 40-60% over several years.

3. Demand and Prescribing Trends

Demand is driven by the drug’s clinical efficacy, safety profile, and insurance reimbursement policies. Growing prevalence of indicated conditions leads to increased prescriptions, boosting revenue potential. Conversely, shifts in clinical guidelines or emerging therapies can reduce demand.

Data from healthcare utilization reports suggest that in indications relevant to NDC 46122-0557, treatment adherence improves with better safety and efficacy profiles, positively impacting consumption volume.

4. Reimbursement and Pricing Pressures

Reimbursement policies influence net prices. CMS and private payers continue to emphasize value-based care and cost-effectiveness analyses, leading to negotiations that favor lower prices. The adoption of value-based contracting and tiered formularies further constrains pricing.

Price Projections

1. Current Pricing Landscape

The average wholesale price (AWP) and wholesale acquisition cost (WAC) serve as pricing benchmarks. For drugs comparable to NDC 46122-0557, WAC ranges between $X and $Y per unit/year, depending on formulation and dosage. Insurers often negotiate discounts, reducing actual transaction prices by approximately 15-20%.

2. Short-term Projections (1-3 Years)

Given current patent protections, minimal biosimilar competition, and stable demand, prices are anticipated to remain relatively steady with minor fluctuations, barring major regulatory or market disturbances.

3. Medium- to Long-term Projections (3-10 Years)

Post-patent expiry, prices are likely to decline significantly due to biosimilar competition. Based on historical data, a reduction of 30-50% over 5-7 years is expected once biosimilars gain substantial market penetration. Additionally, the integration of value-based pricing models and increased affordability initiatives may further influence downward pricing trends.

4. Impact of Emerging Biosimilars and Generics

The entrance of biosimilars, if applicable, could transform the market landscape, challenging the monopoly pricing of the originator product. A competitive market environment coupled with payer-driven discounts can accelerate the decline in net prices.

5. External Economic Factors

Inflation, raw material costs, and supply chain disruptions can influence manufacturing costs, impacting pricing strategies. Recent global events, such as the COVID-19 pandemic, have prompted manufacturers to reevaluate pricing due to increased production costs.

Market Opportunities and Risks

Opportunities:

  • Expansion into emerging markets, where demand for innovative therapies is rising.
  • Development of biosimilar or generic versions to capture market share post-patent expiration.
  • Incorporation into value-based reimbursement models to secure premium pricing during patent exclusivity.

Risks:

  • Entry of biosimilars or generics rapidly eroding prices.
  • Regulatory delays or unfavorable rulings impacting market exclusivity.
  • Negative clinical or safety data reducing prescribing preferences.

Strategic Recommendations

  • Monitor patent landscapes: Active tracking of patent protections and expiration dates to anticipate market entry of biosimilars.
  • Engage in payer negotiations: Early discussions around value-based pricing can secure favorable reimbursement terms.
  • Invest in lifecycle management: Innovate formulations and delivery methods to extend patent life or create new market segments.
  • Expand geographic footprint: Leverage regulatory pathways in emerging markets to diversify revenue streams.

Key Takeaways

  • The current market valuation of NDC 46122-0557 centers on a period of stability driven by patent protection and limited biosimilar competition.
  • Price projections suggest minimal fluctuations in the short term, with significant reductions expected post-patent expiry due to biosimilar entry.
  • Regulatory, clinical, and economic factors are dynamic determinants shaping both current pricing and future trends.
  • Stakeholders should prioritize patent monitoring, reimbursement negotiations, and lifecycle innovations to maximize value.
  • The evolving landscape necessitates proactive strategies aligned with regulatory developments and market entry timelines.

FAQs

Q1: What factors influence the price of NDC 46122-0557 in the current market?
A: Key factors include patent status, competition from biosimilars or generics, demand and prescribing trends, reimbursement policies, and manufacturing costs.

Q2: How soon might biosimilar competition impact the pricing of this drug?
A: If patent protections expire in the next 2-5 years, biosimilar entries could begin affecting pricing within 1-2 years post-expiry, accelerating as market penetration increases.

Q3: What strategies can pharmaceutical companies employ to extend patent life or market exclusivity?
A: Companies can pursue formulation improvements, delivery innovations, patent filings for new uses, or pursue orphan drug designations for extended exclusivity.

Q4: How will healthcare reimbursement policies likely influence future prices?
A: Payer emphasis on value-based care and cost-effectiveness will pressure prices downward, especially if newer therapies demonstrate improved outcomes or cost savings.

Q5: Are there regional considerations that could affect pricing projections?
A: Yes. Developing markets often have less regulatory and reimbursement rigor, potentially allowing higher prices initially but with limited growth, whereas mature markets focus on cost containment, often leading to lower prices.


References

[1] U.S. Food and Drug Administration (FDA). Patent and exclusivity data.

[2] IQVIA. Market Insights and Biosimilar Impact Reports.

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