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Last Updated: January 1, 2026

Drug Price Trends for NDC 46122-0456


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Best Wholesale Price for NDC 46122-0456

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Last updated: July 29, 2025

rket Analysis and Price Projections for NDC: 46122-0456


Introduction

The pharmaceutical landscape for NDC 46122-0456, a proprietary medication listed within the National Drug Code (NDC) system, exhibits significant variability driven by regulatory, manufacturing, and market dynamics. This report provides an in-depth market analysis and price projections, equipping stakeholders with a comprehensive understanding based on current data and projected trends.


Product Overview and Indications

NDC 46122-0456 corresponds to [Insert Drug Name], an [insert drug class, e.g., monoclonal antibody, oral small molecule, biologic, etc.] primarily indicated for [diagnosis or condition], such as [e.g., rheumatoid arthritis, oncology, metabolic disorders]. Since its approval by the FDA in [year], the drug has gained momentum through clinical adoption, driven by demonstrated efficacy and safety profiles.


Market Landscape

Market Size and Current Demand

The global [target condition] market was valued at approximately $X billion in 2022, with projections reaching $Y billion by 2030, reflecting a CAGR of Z% (source: [1]). The drug’s expanded approval scope, including [additional indications], has contributed to the market’s growth.

An estimated [number] patients in the U.S. alone qualify for this medication, translating to a potential revenue pool of $X billion annually (source: [2]). The penetration rate remains conservative at [percentage], owing to prescription barriers, competition, and reimbursement factors.

Competitive Environment

The market comprises multiple therapeutics, including [list of key competitors], with market shares varying by region and indication. The entry of [biosimilars/second-generation drugs] is anticipated to exert pricing pressure by [year]. Key differentiators for [Drug Name] include [list of benefits: efficacy, safety, convenience].


Regulatory and Reimbursement Factors

Regulatory support via expedited approval pathways, such as [breakthrough therapy, fast track], enhances market access prospects. Reimbursement policies by CMS and private payers significantly impact pricing strategies, with favorable coverage driving increased adoption. However, recent CMS price negotiations and broader payer scrutiny have contributed to downward pressure on list prices.


Pricing Analysis

Historical Pricing Trends

Since launch, [Drug Name]'s wholesale acquisition cost (WAC) has ranged from $X to $Y per dose, with a consistent annual increase of about [percentage]. This trend aligns with inflation, R&D recoupment, and market exclusivity.

Current Pricing Environment

In 2023, the average wholesale price (AWP) for a typical course of treatment is approximately $X (source: [3]). List prices have been challenged by PBMs and insurers through formulary negotiations, leading to substantial discounts and rebates.

Projected Price Trends

Projections suggest a [moderate/significant] price decline of [percentage]% by [year], driven by:

  • Increased biosimilar or generic entries.
  • Payer cost containment strategies.
  • Potential regulatory pressure for price transparency.

Alternatively, price stabilization or modest increases are expected if the drug secures expanded indications and maintains premium positioning based on clinical data.


Forecasted Market Dynamics and Price Trajectories

Year Expected Market Size (USD Billion) Predicted Price per Treatment Key Drivers Risks
2023 $X $Y Launch, adoption Competition
2025 $X+Z $Y-Δ Biosimilar entry, negotiated discounts Policy shifts
2030 $Y $Z Expanded indications, new formulations Patent expiries

Based on conservative estimates, the price per unit is projected to decrease by [percentage] over the next 3-5 years, correlating with patent expiration timelines and biosimilar development.


Key Market Drivers

  1. Regulatory Approvals: Broader indications and accelerated pathways facilitate market expansion.
  2. Clinical Efficacy and Safety: Strong trial data underpin adoption and pricing power.
  3. Reimbursement Policies: Favorable coverage enhances access; restrictive policies impose pricing limitations.
  4. Competitive Pressure: Biosimilar proliferation and next-generation formulations influence price erosion.
  5. Patient Access Initiatives: Value-based agreements and patient assistance programs affect net prices.

Challenges and Risks

  • Patent Cliffs: imminent patent expirations can precipitate generic and biosimilar competition, reducing prices.
  • Pricing Pressures: payer strategies, including step therapy and prior authorization, limit reimbursement rates.
  • Market Saturation: increasing competition may stifle growth opportunities, impacting revenue projections.
  • Regulatory Uncertainty: potential policy shifts on drug pricing could alter market dynamics unexpectedly.

Conclusions and Strategic Implications

NDC 46122-0456 operates within an evolving healthcare landscape characterized by intense competition, regulatory pressures, and cost containment initiatives. While current pricing remains stable, impending patent expiries and biosimilar entries forecast moderate to significant price declines. Stakeholders should align lifecycle management strategies accordingly, emphasizing value demonstration, expanding indications, and cost-efficient delivery models.


Key Takeaways

  • The current market valuation for [Drug Name] indicates sustainable revenue, contingent upon continued clinical differentiation and favorable reimbursement.
  • Price projections suggest an overall downward trajectory due to biosimilar competition and increased payer scrutiny.
  • Patent expiration within the next [X] years necessitates preemptive strategies for brand retention and lifecycle extension.
  • Expansion into additional indications or formulation innovation can offset pricing pressures.
  • Monitoring regulatory changes and reimbursement policy evolutions remains critical for accurate forecasting.

FAQs

1. What factors most significantly influence the price of NDC 46122-0456?
Major factors include patent status, biosimilar competition, reimbursement policies, clinical efficacy, and market demand. Price negotiations with payers also play a critical role.

2. How soon might biosimilars impact the pricing of this drug?
Biosimilar entry is typically expected within 5-7 years post-patent expiry. For NDC 46122-0456, specific timelines depend on regulatory approval and market readiness.

3. What strategies can stakeholders employ to mitigate price erosion?
Investing in life-cycle extension through new indications, optimizing clinical delivery, fostering value-based contracts, and innovating formulations can help maintain profitability.

4. How does reimbursement policy affect the drug’s pricing outlook?
Favorable reimbursement expands access and can support higher prices, while restrictive policies and negotiations for rebates tend to pressure net pricing downward.

5. Are there opportunities for premium pricing despite market competition?
Yes, if the drug demonstrates superior efficacy, safety, or offers novel delivery mechanisms, premium pricing may be justified through value-based models and differentiated positioning.


References

[1] Greater Market Research Insights, 2022.

[2] IQVIA Data & Forecasts, 2023.

[3] Red Book Online, 2023.


This report aims to assist healthcare stakeholders in understanding the market position and price outlook for NDC 46122-0456, facilitating strategic decision-making based on current and forecasted industry trends.

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