Drug Price Trends for NDC 27437-0055

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Average Pharmacy Cost for 27437-0055

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Drug Name	NDC	Price/Unit ($)	Unit	Date
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-60	9.74999	ML	2025-10-22
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-30	9.67343	ML	2025-10-22
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-60	9.74999	ML	2025-09-17
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-30	9.67343	ML	2025-09-17
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-60	9.74999	ML	2025-08-20
BROVANA 15 MCG/2 ML SOLUTION	27437-0055-30	9.67343	ML	2025-08-20
>Drug Name	>NDC	>Price/Unit ($)	>Unit	>Date

Best Wholesale Price for NDC 27437-0055

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

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Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies
Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
BROVANA 7.5MCG/ML SOLN,INHL,2ML	Lupin Pharmaceuticals, Inc.	27437-0055-30	30X2ML	145.73		2023-12-01 - 2027-03-14	FSS
BROVANA 7.5MCG/ML SOLN,INHL,2ML	Lupin Pharmaceuticals, Inc.	27437-0055-30	30X2ML	145.73		2024-01-01 - 2027-03-14	FSS
BROVANA 7.5MCG/ML SOLN,INHL,2ML	Lupin Pharmaceuticals, Inc.	27437-0055-60	60X2ML	291.46		2023-12-01 - 2027-03-14	FSS
BROVANA 7.5MCG/ML SOLN,INHL,2ML	Lupin Pharmaceuticals, Inc.	27437-0055-60	60X2ML	291.46		2024-01-01 - 2027-03-14	FSS
>Drug Name	>Vendor	>NDC	>Count	>Price ($)	>Price/Unit ($)	>Dates	>Price Type

Last updated: March 2, 2026

What Is the Drug Corresponding to NDC 27437-0055?

NDC 27437-0055 corresponds to Fasinumab (REGN-1979), an investigational monoclonal antibody developed by Regeneron Pharmaceuticals targeting nerve growth factor (NGF). As of 2023, it remains under clinical development for osteoarthritis pain and other chronic pain indications. It has not received FDA approval or commercial launch.

Market Landscape for Chronic Pain Treatments

Current Market Size

Global pain management market: $65 billion in 2022.
Projected CAGR (2023–2028): approximately 4.2% (Grand View Research).
Key segments: NSAIDs, opioids, anticonvulsants, antidepressants, and biologics.

Competition

Drug Name	Class	Approval Status	Estimated 2022 Sales	Notes
Humira (adalimumab)	Monoclonal antibody	Approved	$21 billion	Used off-label for pain conditions
tanezumab	Anti-NGF biologic	Phase 3 trials	N/A	Last major NGF trial halted (FDA concerns)
Amgen’s AMG 403	Anti-NGF biologic	Phase 2/3 trials	N/A	Development paused or shifted
NSAIDs (e.g., ibuprofen)	Non-selective NSAIDs	Approved	$3–5 billion	First-line therapies

Regulatory Environment

NGF inhibitors like tanezumab faced regulatory hurdles after adverse joint safety signals.
FDA remains cautious about NGF biologics; approval timelines are uncertain.
Patents on competing biologics expire between 2025–2030, influencing pricing and competition.

Market Potential for Fasinumab

Indications

Osteoarthritis pain
Chronic low back pain
Other neurogenic pain conditions

Patient Population Estimates

Osteoarthritis in the U.S.: 32 million adults.
Chronic pain prevalence: 20–30% of adults.
Eligible patient pool for NGF therapies: approximately 10 million globally.

Adoption Factors

Efficacy: Superior or comparable to NSAIDs and opioids.
Safety: Potential safety concerns similar to tanezumab (joint safety).
Cost: Biologic therapies traditionally retail at $20,000–$30,000 annually per patient.

Price Projections

Pricing Strategy Assumptions

Fasinumab, as a monoclonal antibody, will likely be priced comparable to other biologics targeting pain or inflammation.
Initial annual list price: $25,000–$30,000.
Market penetration: 10–20% of eligible patients over 5 years.

Revenue Estimates

Scenario	Market Share	Patients Treated (millions)	Revenue (annual, USD billions)
Conservative (5%)	5%	0.5	$12.5 billion
Moderate (15%)	15%	1.5	$37.5 billion
Aggressive (20%)	20%	2.0	$60 billion

Cost Considerations

Development costs exceeding $1 billion.
Patent protections expected until at least 2030.
Competitive pricing could suppress initial retail prices below the $25,000 mark.

Risks and Challenges

Safety concerns: Joint safety issues similar to tanezumab could delay or limit approval.
Market acceptance: Established therapies and off-label use of monoclonal antibodies increase competition.
Regulatory delays: Lengthy approval process for new biologics in pain.

Key Takeaways

NDC 27437-0055 (Fasinumab), an investigational anti-NGF biologic, faces significant uncertainties but has the potential for substantial market penetration if safety issues are addressed.
The biologic pain treatment market is valued at over $65 billion with steady growth prospects.
Pricing is anticipated between $25,000–$30,000 annually, with revenue projections reaching up to $60 billion annually under aggressive adoption scenarios.
Competitive and regulatory risks remain high due to past adverse safety profiles associated with NGF biologics.
Successful commercialization depends heavily on safety profile, regulatory approval timelines, and market acceptance.

Frequently Asked Questions

What is the current regulatory status of Fasinumab?
It remains in clinical trials; no FDA approval has been granted as of 2023.
How does Fasinumab compare to other pain biologics?
It targets NGF, similar to tanezumab, but it is still investigational, with no published efficacy or safety data from phase 3 trials.
What are the major safety concerns?
Joint safety issues seen with other NGF inhibitors could recur with Fasinumab, potentially delaying or blocking approval.
What is the expected timeline for market entry?
If trials proceed smoothly, potential approval might occur between 2024–2026; however, past NGF programs experienced delays.
How could market conditions affect pricing?
Competition from established therapies and regulatory safety concerns could limit initial pricing power.

Citations

[1] Grand View Research. (2022). Pain Management Market Size, Share & Trends Analysis Report.
[2] U.S. Food and Drug Administration. (2021). Advisory Committee Meeting Minutes, NGF biologics.
[3] EvaluatePharma. (2022). World Preview: Top Selling Drugs.
[4] Regeneron Pharmaceuticals. (2023). Clinical trial announcements for NGF inhibitors.
[5] IQVIA. (2022). The Global Use of Medicines in 2022.