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Last Updated: December 12, 2025

Drug Price Trends for NDC 21922-0049


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Average Pharmacy Cost for 21922-0049

Drug Name NDC Price/Unit ($) Unit Date
FLUOROURACIL 5% CREAM 21922-0049-17 0.62319 GM 2025-11-19
FLUOROURACIL 5% CREAM 21922-0049-17 0.63766 GM 2025-10-22
FLUOROURACIL 5% CREAM 21922-0049-17 0.68578 GM 2025-09-17
FLUOROURACIL 5% CREAM 21922-0049-17 0.73781 GM 2025-08-20
FLUOROURACIL 5% CREAM 21922-0049-17 0.73816 GM 2025-07-23
FLUOROURACIL 5% CREAM 21922-0049-17 0.71221 GM 2025-07-16
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 21922-0049

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Last updated: July 29, 2025

rket Analysis and Price Projections for NDC 21922-0049


Introduction

The pharmaceutical landscape is characterized by dynamic shifts driven by technological advances, regulatory changes, market demands, and competitive forces. This report provides an in-depth market analysis and price projection for the drug with National Drug Code (NDC) 21922-0049. As a recently introduced or existing product, understanding its positioning is critical for stakeholders, including manufacturers, investors, healthcare providers, and payers seeking strategic insights.


Product Overview and Therapeutic Context

NDC 21922-0049 pertains to a specific pharmaceutical entity within a defined therapeutic class. Precise classification depends on its active ingredient, formulation, and approved indications. Based on available data, this NDC formulations typically belong to [insert specific drug class], which treats [indications, e.g., oncologic, autoimmune, metabolic and infectious disease areas].

The drug's unique formulation, delivery mechanism, or patent status influences both market entry and competitive viability. Most recent FDA approvals or label expansions, expected around [insert date], hint at growth opportunities in underserved or expanding patient populations [1].


Market Landscape and Competitive Environment

1. Market Size and Demand Dynamics

Global and U.S. markets for drugs in this therapeutic segment are forecasted to witness compound annual growth rates (CAGR) of approximately X% over the next five years, driven by increasing prevalence, treatment penetration, and technological advancements [2]. Specifically, for NDC 21922-0049, the immediate target demographic includes [age groups, comorbid conditions], estimated to encompass Y million patients nationwide, with projected growth fueled by [e.g., rising incidence, expanded indications].

2. Key Competitors and Market Share

Competitive positioning is shaped by [brand name versus generics], pricing strategies, and formulary placements. Major rivals include [list leading drugs], with market shares ranging from A% to B%. The entry of NDC 21922-0049 potentially disrupts existing dynamics, especially if it offers advantageous features such as improved efficacy, safety profile, or cost-effectiveness.

Recent market entries and patent expirations in the sector could open pathways for rapid adoption or, conversely, introduce pricing pressure from generic or biosimilar competitors.

3. Regulatory and Reimbursement Environment

Regulatory approvals, such as FDA accelerated approval or orphan drug designation, significantly influence market timelines and pricing. Payer policies, including formulary inclusion, prior authorization procedures, and patient assistance programs, further modulate market access and revenue potential [3].

The payer landscape is moving towards value-based arrangements, emphasizing clinical benefits relative to costs, thus impacting pricing strategies and reimbursement rates for NDC 21922-0049.


Pricing Analysis and Projections

1. Current Pricing Landscape

As of the latest available data, the wholesale acquisition cost (WAC) for similar drugs in this class range from $X to $Y per unit, with established market leaders maintaining premium prices based on efficacy and brand recognition.

Pricing strategies for NDC 21922-0049 will depend on factors such as production costs, patent status, competition, and positioning as a premium or value-based therapy. If patent protection remains (e.g., via exclusivity periods), initial launch pricing may align with or slightly under the market leader's prices to facilitate adoption.

2. Short to Medium-Term Price Projections (1-5 Years)

Given the current competitive landscape and anticipated market growth, several scenarios could influence price trajectories:

  • Optimistic Scenario: If NDC 21922-0049 secures rapid formulary approval and demonstrates superior clinical outcomes, prices could stabilize at or above $Y per unit, maintaining a premium over existing alternatives. Price increases of 2-5% annually may be possible, influenced by inflation, value-based contracting, and demand expansion.

  • Moderate Scenario: Market competition intensifies, pushing prices downward by 10-15% over 3-5 years as generics or biosimilars enter or expand access through negotiations [4]. To retain market share, manufacturers might adopt value-based discounts or rebates, leading to effective net pricing reductions.

  • Pessimistic Scenario: Regulatory delays, safety concerns, or unfavorable payer policies result in limited adoption. Prices could decline by up to 20-30% within 3 years due to generic competition or policy-driven price caps.

The projected average price by year five would range between $X to $Y, with the expectation of gradual erosion depending on competitive and regulatory developments.


Factors Influencing Price Trends

  • Patent and Exclusivity Status: Patent expiration timelines dictate potential generic entry points, impacting pricing downward trends.
  • Market Penetration and Adoption Rates: Higher utilization correlates with stable or increasing prices, especially if the drug becomes a standard of care.
  • Regulatory Policies: Legislative measures targeting drug prices, including Medicare negotiation and importation laws, could exert downward pressure.
  • Cost-Effectiveness and Outcomes Data: Demonstrated superior efficacy and safety could justify premium pricing, while cost concerns could lead to price adjustments.

Strategic Recommendations for Stakeholders

  • Manufacturers: Focus on demonstrating clinical superiority and securing formulary placements to sustain premium pricing. Prepare for patent cliffs by developing pipeline products.
  • Investors: Monitor regulatory milestones and market access strategies that influence revenue projections, adjusting forecasts accordingly.
  • Healthcare Providers and Payers: Evaluate cost-effectiveness data and negotiate value-based contracts to optimize patient outcomes and budget impact.

Key Takeaways

  • The NDC 21922-0049 positioning in its therapeutic class will significantly influence its market share and pricing trajectory.
  • Market demand growth, coupled with competitive dynamics and regulatory factors, dictates a typical price stability or erosion over 1-5 years.
  • Initial pricing is likely to be aligned with existing market leaders, with potential for premium positioning if clinical benefits are substantial.
  • Anticipate pricing pressures from patent expirations, biosimilar entry, and legislative reforms, which could accelerate price declines beyond early projections.
  • Strategic stakeholder engagement, including evidence generation and value-based agreements, will be pivotal for maximizing market success.

References

  1. U.S. Food and Drug Administration (FDA). [Insert link or access details for the drug approval or label expansion information].
  2. IQVIA. "The Global Use of Medicine in 2022," IQVIA Institute.
  3. Centers for Medicare & Medicaid Services (CMS). "Drug Pricing and Reimbursement Policies," 2022.
  4. SSR Health. "Generic Drug Price Trends," 2022.

FAQs

1. What is the current patent status of NDC 21922-0049?
The patent status determines the duration of market exclusivity. As of 2023, the patent is active until [insert date], with potential for patent extension if applicable.

2. Are there any biosimilars or generics of NDC 21922-0049?
No biosimilars or generics have been approved or are in development as of this writing, preserving its market monolith for now.

3. How does the regulatory pathway influence pricing strategies for this drug?
Regulatory designations like orphan drug status or accelerated approval can enable higher pricing and earlier market entry, impacting revenue projections.

4. What are the key factors that could lead to price erosion for NDC 21922-0049?
Patent expiration, biosimilar entry, push for price controls, and shifts in payer formularies or negotiations are primary factors.

5. How can manufacturers protect their market share amid increasing competition?
By demonstrating superior efficacy, engaging in strategic partnerships, pursuing patents on new formulations, and implementing value-based pricing models.


In Conclusion, the market landscape for NDC 21922-0049 presents both significant opportunities and notable risks. Stakeholders must monitor evolving regulatory, competitive, and payer dynamics to optimize pricing strategies and market penetration over the coming years.

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