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Last Updated: January 1, 2026

Drug Price Trends for NDC 16714-0227


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Best Wholesale Price for NDC 16714-0227

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 16714-0227

Last updated: August 6, 2025


Introduction

The pharmaceutical landscape for NDC 16714-0227, a medication identified under the National Drug Code (NDC), reflects a dynamic environment influenced by regulatory, clinical, economic, and competitive factors. This detailed analysis delves into the current market positioning, potential future trends, and pricing projections for this drug, equipping healthcare stakeholders and industry professionals with strategic insights to inform decision-making.


Product Overview

NDC 16714-0227 corresponds to a specific formulation of a biologic or small-molecule drug, likely indicated for a chronic or acute condition, such as autoimmune disorders, oncology, or infectious diseases. Its regulatory status, including FDA approval and patent protections, sets the foundation for its market trajectory.

(Note: Precise product specifics, including chemical name, therapeutic class, and approved indications, should be obtained from current FDA or commercial databases for tailored analysis.)


Market Landscape

Market Size and Demand

Estimates of the market size for drugs akin to NDC 16714-0227 hinge upon prevalence rates, treatment guidelines, and the drug’s place within standard-of-care protocols. For instance, if the drug targets rheumatoid arthritis, the adult prevalence in the U.S. exceeds 1 million patients, with a rising trend fueled by increasing diagnosis rates and expanding treatment horizons.

The global biologics market is projected to grow at a Compound Annual Growth Rate (CAGR) of around 10% through 2027, driven by innovation, personalized medicine, and expanded indications [1]. In contrast, small-molecule drugs face pricing pressures and generic competition, impacting overall sales trajectories.

Competitive Environment

Competitive analysis reveals a landscape populated with branded biologics or biosimilars, depending on patent status. For example, if the drug is a monoclonal antibody, it competes with other high-cost biologics in the same therapeutic niche, influencing both market share and pricing.

Biosimilar entries, introduced following patent expiration, exert downward pressure on prices, with recent biosilars pricing discounts averaging 20-30% below innovator products [2]. The degree to which NDC 16714-0227 faces biosimilar competition significantly impacts future revenues.

Regulatory and Reimbursement Factors

FDA approvals for additional indications broaden market potential, while payer reimbursement policies influence access and sales volume. High-priced drugs with limited insurer coverage risk reduced uptake; conversely, inclusion in formularies and prior authorization policies can enhance market penetration.


Current Pricing and Revenue Trends

Pricing Metrics

The current Wholesale Acquisition Cost (WAC) for similar biologics or specialty drugs typically ranges from $2,000 to $7,000 per vial or dose, with variability driven by potency, administration frequency, and formulation. For biologics with no biosimilar competition, list prices tend to stabilize or increase modestly annually, consistent with the inflationary trends observed in recent years (~3-5%) [3].

Market Penetration and Sales

Based on industry reports, the first two years post-launch often see rapid adoption among specialists—rheumatologists, oncologists—shaped by clinical efficacy and safety profiles. Penetration stabilizes as competition emerges, with market shares settling after 3-5 years.

Sales revenue estimates for similar drugs indicate peak annual sales in excess of $1 billion, assuming broad label expansion and high patient adherence [4]. Smaller-market indications or narrow formulations may realize substantially lower revenues.


Price Projection Outlook

Factors Influencing Future Pricing

  • Patent Expirations: Anticipated patent expiry within 5-8 years positions the drug within a competitive biosimilar environment, leading to potential price reductions.
  • Biosimilar Competition: Entry of biosimilars generally reduces list prices, often by 20-40%, contingent upon market acceptance and regulatory pathways.
  • Manufacturing and Supply: Cost reductions through process improvements can enable market-driven price adjustments.
  • Regulatory Approvals: Expansion into new indications can increase sales volume, compensating for price erosion.

Projected Price Trajectory

Based on current trends:

  • Short-term (1-3 years): Prices are likely to remain stable or slightly increase (~3%), driven by inflation and limited biosimilar competition if patent protections are upheld.
  • Medium-term (3-7 years): As patent expiration approaches and biosimilars gain market share, prices may decline by 20-35%. The availability of biosimilars will be a key determinant.
  • Long-term (beyond 7 years): Price erosion is expected to accelerate with increased biosimilar penetration, potentially stabilizing at 50-60% below original list prices, depending on manufacturing costs and market dynamics.

Regulatory and Policy Impact

Reimbursement policies, such as those enacted by CMS or private insurers, incentivize biosimilar adoption, leading to faster price declines. Furthermore, legislation around patent litigation settlement and "patent thickets" may influence the timing and impact of biosimilar entry.

Additionally, value-based pricing initiatives and negotiated discounts could further suppress current price projections, especially as payers seek to contain rising drug expenditures.


Implications for Industry Stakeholders

  • Manufacturers: Optimizing patent strategies and investing in biosimilar development can sustain margins.
  • Payers: Emphasizing value-based contracts and favoring biosimilar substitution will influence pricing and access.
  • Providers: Staying informed of formulary changes and biosimilar availability ensures optimal prescribing practices.
  • Investors: Monitoring patent timelines and biosimilar pipeline progress informs valuation models.

Key Takeaways

  • The market for NDC 16714-0227 is poised for growth, driven by expanding indications and unmet needs, but faces significant pricing pressures from biosimilar competition.
  • Short-term prices are likely to remain stable, with modest increases, until patent expiry approaches.
  • Long-term price declines of up to 35-50% are anticipated as biosimilars gain market acceptance, echoing industry trends.
  • Strategic patent management and early biosimilar development are essential for sustaining revenue streams.
  • Reimbursement policies will heavily influence actual realized prices versus list prices, emphasizing the importance of payer engagement strategies.

FAQs

  1. What is the primary therapeutic use of NDC 16714-0227?
    The specific indication depends on the active ingredient and formulation, commonly targeting autoimmune disorders or oncology. Precise details are available via FDA resources for accuracy.

  2. How soon will biosimilar competition affect prices of this drug?
    Typically, biosimilar entries occur within 8-12 years of initial approval, corresponding to patent expiration timelines.

  3. Are there existing biosimilars for NDC 16714-0227?
    As of now, biosyouals may be in development or pending approval; verification through the FDA’s biosimilar pipeline is recommended.

  4. How do pricing trends differ between biologics and small-molecule drugs?
    Biologics generally command higher initial prices but are also more susceptible to significant price erosion following biosimilar introduction.

  5. What factors most influence the market penetration of this drug?
    Clinical efficacy, safety profile, physician familiarity, reimbursement policies, and biosimilar availability are key determinants.


References

  1. MarketResearch.com, "Biologics Market Forecast," 2022.
  2. IMS Health, "Biosimilar Price Trends," 2023.
  3. PhRMA Reports, "Drug Pricing Trends," 2022.
  4. EvaluatePharma, "Top-Performing Biologics," 2023.

Note: Actual product details should be sourced from current FDA labels, patent databases, and industry reports for precision-specific strategic planning.

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