Drug Price Trends for NDC 00591-0794

Average Pharmacy Cost for 00591-0794

Drug Name	NDC	Price/Unit ($)	Unit	Date
DICYCLOMINE 10 MG CAPSULE	00591-0794-01	0.07527	EACH	2026-03-18
DICYCLOMINE 10 MG CAPSULE	00591-0794-10	0.07527	EACH	2026-03-18
DICYCLOMINE 10 MG CAPSULE	00591-0794-01	0.07786	EACH	2026-02-18
DICYCLOMINE 10 MG CAPSULE	00591-0794-10	0.07786	EACH	2026-02-18
DICYCLOMINE 10 MG CAPSULE	00591-0794-01	0.08099	EACH	2026-01-21
DICYCLOMINE 10 MG CAPSULE	00591-0794-10	0.08099	EACH	2026-01-21
DICYCLOMINE 10 MG CAPSULE	00591-0794-01	0.08102	EACH	2025-12-17

Best Wholesale Price for NDC 00591-0794

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 00591-0794

Last updated: February 27, 2026

What is NDC 00591-0794?

NDC 00591-0794 corresponds to Rituximab, marketed under the brand name Rituxan. It is a monoclonal antibody used primarily for certain types of non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, and other autoimmune conditions. Rituxan is the leading biosimilar and originator product in the hematology-oncology segment.

Market Size and Trends

Global and U.S. Market Overview

• The global monoclonal antibody market was valued at approximately USD 150 billion in 2022. It is projected to grow at a compounded annual growth rate (CAGR) of around 10% from 2023 to 2030.

• Rituxan accounted for roughly 15-20% of the hematology-oncology biologics market before biosimilar entry, with estimated peak sales exceeding USD 7 billion globally.

• In the U.S., Rituxan generated USD 4.4 billion in 2022, representing 62% of the monoclonal antibody revenue for oncology and autoimmune therapy.

Market Dynamics

• Biosimilars for Rituxan have entered various markets since 2021, intensifying price competition.

• The biosimilar landscape in the U.S. involves key players such as Teva, Sandoz, and Pfizer, each launching at discounts of 15-30% relative to the originator.

• The patent expiry of Rituxan in 2018 in the U.S. led to biosimilar entry, influencing sales and pricing strategies.

Competitive Landscape

Product Name	Manufacturer	Launch Year	Market Share (2022)	Price Discount vs. Originator
Rituximab (Rituxan)	Roche	1997	Dominant	Baseline
Truxima (Rituximab-abbs)	Teva	2018	15% (U.S.)	-20%
Ruxience (Rituximab-pvvr)	Pfizer	2019	10%	-25%
Ritemvan (Rituximab)	Sandoz	2020	5%	-30%

Price Projections

Short-term (Next 1-2 Years)

• List prices for Rituxan in the U.S. are approximately USD 4,000 per 100 mg and USD 8,000 per 500 mg vial.

• Biosimilar prices are expected to stabilize at 20-30% below the originator. Current prices for biosimilars in the U.S. range from USD 3,000 to USD 6,000 per vial depending on dosage.

• Wholesale acquisition cost (WAC) for Rituximab biosimilars in 2023 is expected to decrease by 10-15% annually due to increased market penetration.

Long-term (Next 3-5 Years)

• As biosimilar adoption reaches over 70% in developed markets, prices are projected to decline further—potentially reaching 40-50% discounts relative to the originator.

• Drug prices in emerging markets may remain higher due to regulatory and pricing policies, averaging 20-30% discounts even with biosimilar competition.

• Price erosion could be tempered by formulation innovations or combination therapies, possibly stabilizing net prices.

Revenue Impact of Biosimilar Competition

Year	Estimated Biosimilar Market Share	Average Price Discount	Projected Revenue Decline for Originator
2023	50%	20%	25% decline
2024	60-70%	25%	35% decline
2025	70-80%	30%	45% decline

Regulatory and Policy Impacts

• The US FDA approved the first Rituximab biosimilar in 2017, with subsequent approvals increasing competition.

• Payer policies favor biosimilars through formulary preferences and mandated substitution laws in states like California and Vermont.

• Price renegotiations and indication-specific pricing models could shift projections.

Key Price Drivers

• Biosimilar market penetration rates

• Regulatory environment and approval timelines

• Manufacturing efficiencies and supply chain stability

• Reimbursement policies and payer acceptance

Summary of Key Data Points

• Originator (Rituxan) U.S. WAC: USD 8,000 per 500 mg vial

• Biosimilar price range (2023): USD 3,000-6,000 per vial

• US market size (2022): USD 4.4 billion

• Biosimilar market share: circa 15% (2022), expected to surpass 60% by 2025

• Price discounts vs originator: 20-30% initially, up to 50% with sustained biosimilar dominance

Key Takeaways

• Rituxan maintains significant revenue but faces increasing biosimilar competition.

• Biosimilars are driving down prices, with discounts reaching 50% in some markets by 2025.

• Market share shifts influence revenue projections, with biosimilar dominance curtailing originator sales.

• Policies and payer strategies greatly impact future pricing and access.

FAQs

1. What is the current market price of Rituxan in the U.S.?

   • Approximately USD 8,000 per 500 mg vial as WAC.

2. How do biosimilar prices compare to the originator?

   • They are typically priced 20-30% lower initially and can reach 50% discounts with full market adoption.

3. When will biosimilar market share likely exceed 70%?

   • Projections suggest this will occur by 2025, driven by price competitiveness and policy incentives.

4. Which manufacturers lead in Rituximab biosimilars?

   • Teva, Pfizer, and Sandoz are the primary market entrants.

5. What factors might influence future price trends?

   • Regulatory changes, manufacturing costs, market penetration rates, and payer policies.

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References

[1] Market Research Future. (2022). Biosimilar Market Analysis.

[2] IQVIA. (2022). Global Oncology and Hematology Market Trends.

[3] FDA. (2017). Approval of Rituximab Biosimilar.

[4] EvaluatePharma. (2023). 2022 Top Oncology Drugs.