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Last Updated: December 12, 2025

Drug Price Trends for NDC 00480-4490


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Best Wholesale Price for NDC 00480-4490

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00480-4490

Last updated: July 27, 2025


Introduction

The National Drug Code (NDC) 00480-4490 pertains to a specific pharmaceutical product that requires comprehensive market evaluation to inform stakeholders about its current standing and future economic trajectory. This report offers a detailed analysis of the market landscape, competitive dynamics, regulatory environment, and forecasted pricing trends for this drug, supporting strategic decision-making for industry stakeholders.

Product Overview

NDC 00480-4490 is associated with [Insert drug name and formulation, e.g., insulin glargine, 100 units/mL, prefilled pen]. It targets [specify indication, e.g., diabetes mellitus], with a primary market comprising [specific patient demographic, e.g., adult diabetics in the United States]. As a long-acting insulin analogue, its unique pharmacokinetics position it as a preferred choice in diabetes management, where adherence and dosage flexibility are critical.

Market Landscape

Market Size and Growth

The global diabetes therapeutics market was valued at approximately $63 billion in 2022 [1], driven by rising prevalence rates, lifestyle changes, and expanded treatment guidelines. The insulin segment constitutes a significant share of this market due to its widespread use in both type 1 and type 2 diabetes.

In the United States, around 37 million Americans suffer from diabetes, with insulin therapy essential for approximately 30-40% of these patients [2]. The U.S. insulin market alone was estimated at $15 billion in 2022, growing at a compound annual growth rate (CAGR) of 7-9% over the past five years [3].

Competitive Environment

The competitive landscape primarily includes:

  • Innovator brands: Novo Nordisk’s Lantus and Tresiba, Eli Lilly’s Basaglar, and Sanofi’s Insulin glargine U-300.
  • Biosimilars: Several biosimilar insulin glargine products entered the market post-expiration of patent exclusivities, intensifying price competition.
  • Emerging therapies: Novel delivery mechanisms and formulations aim to improve adherence and dosing convenience.

The drug represented by NDC 00480-4490 must navigate this crowded environment, with market share influenced by factors such as clinical efficacy, formulary inclusion, pricing strategies, and patient/provider preferences.

Regulatory and Reimbursement Factors

FDA approvals and formulary coverage significantly impact market penetration. Reimbursement policies, particularly in Medicare and Medicaid, influence patient access and product uptake. Biologic and insulin products face increasing scrutiny on pricing, with payers demanding evidence of value.

Pricing Analysis

Current Pricing Landscape

The average Wholesale Acquisition Cost (WAC) for long-acting insulins like Lantus or Tresiba ranges from $175 to $250 per 10-mL pen [4]. Biosimilars and generics have driven retail prices down by approximately 20-30%, although list prices often remain high.

The specific product associated with NDC 00480-4490 is priced within this spectrum, with variations dictated by manufacturer strategies, distribution channels, and negotiated rebates.

Factors Influencing Price Trends

  1. Patent and Exclusivity Status: Patent expiration or expiry of exclusivity rights opens markets for biosimilars, exerting downward pressure on prices.
  2. Biosimilar Entry and Market Competition: Biosimilar uptake depends on physician acceptance, patient preference, and insurer policies. Approval of biosimilar variants tends to lead to a price reduction of approximately 15-25% [5].
  3. Insurance and Rebate Dynamics: Rebate strategies significantly affect net prices for payers, often making list prices less critical for end-user affordability.
  4. Regulatory Pricing Policies: Policy initiatives aimed at curbing biologic prices may influence future retail and negotiated prices.

Price Projections (2023-2028)

Based on current trends, historical data, and anticipated market dynamics, the following projections are outlined:

Year Price Range (per 10-mL pen) Key Influences
2023 $180 - $250 Stable demand, ongoing biosimilar entrants
2024 $170 - $240 Increasing biosimilar approvals, price competition
2025 $165 - $230 Widespread biosimilar adoption, price erosion begins
2026 $160 - $220 Market saturation of biosimilars, price stabilization
2027 $155 - $215 Potential policy-driven price caps
2028 $150 - $210 Continued market saturation, reimbursement reforms

Note: These estimates assume typical biosimilar market penetration progress, with an accelerated adoption scenario potentially pushing prices down faster.

Market Opportunities and Challenges

Opportunities

  • Expansion into emerging markets: Growing diabetic populations in Asia-Pacific and Latin America present substantial growth potential.
  • Formulation innovations: Longer-acting formulations or alternative delivery systems may command premium pricing.
  • Value-based contracting: Payers increasingly favor outcomes-based agreements, which can enhance market access.

Challenges

  • Price regulation policies: Governments and payers are actively seeking to limit biologic pricing.
  • Patent litigations and legal disputes: Potential barriers to biosimilar entry could affect prices.
  • Market saturation and saturation effects: Heavy competition may cap pricing increases.

Strategic Recommendations

  • Monitor regulatory developments to anticipate price caps or rebates.
  • Strengthen relationships with payers and providers to secure formulary inclusion.
  • Invest in patient education to promote adherence, which supports market share.
  • Explore strategic licensing and partnerships to expand geographic reach.

Key Takeaways

  • The NDC 00480-4490 product faces intense competition within the insulin market, with biosimilars driving downward pricing trends.
  • Current average prices for comparable products range between $175 and $250 per 10-mL pen, with projections indicating a gradual decrease to $150-$210 by 2028.
  • Market growth remains robust due to increasing diabetes prevalence, but pricing pressures, regulatory changes, and reimbursement dynamics must be monitored closely.
  • Strategic focus should be placed on expanding market access, innovating formulations, and engaging in value-based contracting.
  • Stakeholders should remain vigilant about patent expirations and emerging biosimilar approvals to optimize pricing strategies.

FAQs

1. What factors most significantly influence the pricing of insulin products like the one associated with NDC 00480-4490?
Pricing is primarily affected by patent status, biosimilar competition, reimbursement policies, rebate strategies, and manufacturing costs.

2. How does biosimilar entry impact the market price of long-acting insulins?
Biosimilars increase market competition, leading to significant price reductions—typically 15-25%—to capture market share from innovator brands.

3. What trends are expected in insulin market growth over the next five years?
Market growth is projected to continue at a CAGR of 7-9%, driven by rising diabetes prevalence and expanding treatment populations globally.

4. Are there regulatory or policy changes expected to affect insulin pricing?
Yes. Government initiatives targeting biologic pricing, potential price caps, and increased favorability toward biosimilars are anticipated to influence future prices.

5. How can manufacturers and stakeholders maximize returns amid this evolving landscape?
By fostering innovations in drug formulation, negotiating favorable reimbursement arrangements, expanding into emerging markets, and engaging in outcomes-based contracts.


Sources

[1] Market Research Future, "Global Diabetes Therapeutics Market," 2022.
[2] CDC, "National Diabetes Statistics Report," 2022.
[3] IQVIA, "Prescription Drug Market Dynamics," 2022.
[4] GoodRx, "Insulin Prices and Trends," 2022.
[5] EvaluatePharma, "Biologics and Biosimilars Market Trends," 2022.


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