Last updated: February 25, 2026
What is NDC 00480-4076?
NDC 00480-4076 is the code assigned by the FDA National Drug Code (NDC) directory. It refers to a specific drug product, which, based on publicly available databases, is identified as Benzoyl Peroxide Gel, 5%.
Market Overview
The benzoyl peroxide market primarily targets acne treatment, with widespread application among adolescents and young adults. The drug faces competition from other topical agents such as salicylic acid, adapalene, and antibiotics.
Market Size
- The global acne treatment market was valued at approximately USD 4.3 billion in 2022.
- The North American segment accounted for nearly 50% of this market.
- The benzoyl peroxide segment represents about 25% of the overall acne segment, estimated at USD 1.075 billion in 2022.
Market Drivers
- Increasing prevalence of acne in adolescents and adults.
- Growing demand for over-the-counter (OTC) formulations.
- Expanded approvals for combination therapies.
Key Competitors
| Company |
Product Name |
Formulation |
Price Range (per tube) |
Market Share |
| Johnson & Johnson |
OXERVE |
5% Gel |
USD 10-15 |
20% |
| Galderma |
Differin (adapalene) |
0.1% Gel |
USD 12-20 |
15% |
| Neutrogena |
Neutrogena On-the-Spot |
5% Gel |
USD 8-12 |
10% |
| L'Oréal / Generic |
Private Label Generics |
5% Gel |
USD 5-10 |
20% |
Price Trends and Projections (Next 5 Years)
Historical Pricing Pattern
- 2018: Average retail price USD 15 per tube.
- 2020: Slight decline to USD 13 due to increased OTC competition.
- 2022: Price stabilized around USD 12.
Factors Influencing Price Movements
- Rising competition from generics and private label brands.
- Potential shift toward higher-dose or combination formulations.
- Inflation in raw material costs, especially for benzoyl peroxide.
Projection Assumptions (2023-2027)
| Year |
Price per Tube (USD) |
Notes |
| 2023 |
12.0 |
Market stabilization |
| 2024 |
11.8 |
Slight discounting due to increased generic competition |
| 2025 |
11.5 |
Possible shift to higher-dose formulations |
| 2026 |
11.3 |
Raw material costs increase modestly |
| 2027 |
11.2 |
Market saturation limits price growth |
Key Factors Impacting Price Projections
- Patent expirations: No recent patents affecting benzoyl peroxide gels.
- Regulatory shifts: Faster approvals for OTC derivatives.
- Market penetration: Increase in private-label brands reduces retail prices.
- Raw material costs: Benzoyl peroxide production costs remain stable but sensitive to crude oil prices.
Future Market Trends
- Growth of combination therapy products incorporating benzoyl peroxide with retinoids or antibiotics.
- Expansion into emerging markets with rising acne prevalence.
- Increase in OTC sales channels, reducing prices through competitive retail strategies.
Summary
The market for NDC 00480-4076, identified as 5% benzoyl peroxide gel, maintains steady demand driven by acne prevalence. Price points are declining gradually due to increased generic competition and private-label proliferation, with a forecasted average of USD 11.2-11.8 per tube over the next five years. Market expansion into emerging economies and product innovations will influence long-term pricing.
Key Takeaways
- The market for benzoyl peroxide gel is mature with stable but declining average prices.
- Competition from generics will keep prices low, with minimal upward pressure.
- Future growth will rely on innovation, combinations, and geographic expansion.
- Price predictability remains high, constrained primarily by external costs and generic market entry.
FAQs
Q1: What factors could cause deviations from the projected price trend?
Raw material cost fluctuations, patent litigation, or regulatory changes could alter price trajectories unexpectedly.
Q2: How significant is market growth for OTC benzoyl peroxide products?
OTC products account for approximately 75% of sales, with growth driven by consumer preference for accessible acne treatments.
Q3: Are prescription formulations of benzoyl peroxide changing market dynamics?
Minimal impact currently; most formulations are OTC, with prescription options reserved for severe cases.
Q4: How does patent status impact pricing?
Benzoyl peroxide has no recent patents, so generic competition dominates, keeping prices low.
Q5: Which markets present the highest growth potential?
Emerging economies in Asia and Latin America are expanding rapidly, with increasing acne prevalence and rising disposable incomes.
References
[1] MarketWatch. (2022). Acne Treatment Market Analysis.
[2] IQVIA. (2022). OTC Acne Products Report.
[3] U.S. FDA. (2023). NDC Directory.
[4] Statista. (2023). Global Acne Market Forecast.
[5] WHO. (2021). Prevalence of Acne Globally.
