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Drug Price Trends for NDC 00074-1069
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Average Pharmacy Cost for 00074-1069
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| SKYRIZI 360 MG/2.4 ML ON-BODY | 00074-1069-01 | 9088.72500 | ML | 2025-12-17 |
| SKYRIZI 360 MG/2.4 ML ON-BODY | 00074-1069-01 | 9069.04478 | ML | 2025-01-02 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00074-1069
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 00074-1069
Executive Summary
This analysis evaluates the current market landscape and projects the future pricing trends for the drug under NDC 00074-1069, identified as Rotigotine Transdermal System (Neupro). Given its indications for Parkinson’s disease (PD) and restless legs syndrome (RLS), the drug maintains a significant role within neurology therapeutic areas. The analysis covers key market dynamics, competitive landscape, manufacturing considerations, pricing strategies, and regulatory impacts, providing actionable insights for stakeholders.
What is NDC 00074-1069?
Non-Drug Code (NDC): 00074-1069
Product Name: Rotigotine Transdermal System (Neupro)
Manufacturer: UCB Pharma
Formulation: Transdermal patch
Indications:
- Parkinson’s disease (PD)
- Restless legs syndrome (RLS)
Approval Status: Fully approved by the FDA (since 2012) with subsequent labeling updates
Market Overview: Current Landscape
Global and U.S. Market Size
| Parameter | 2022 Estimate | Notes |
|---|---|---|
| Global Parkinson’s Drug Market | $4.8 billion | CAGR 5% (2022-2027) [1] |
| U.S. Parkinson’s Market | ~$2.1 billion | Leading region, high prevalence in elderly [2] |
| Restless Legs Syndrome (RLS) Market | ~$600 million | Increasing diagnosis, mainly off-label use [3] |
Sources:
[1] Market Data Forecast, 2022
[2] Parkinson’s Foundation, 2022
[3] Grand View Research, 2022
Market Drivers
- Aging population globally elevates PD and RLS prevalence
- Advances in transdermal drug delivery improve compliance
- Growing preference for non-oral dopaminergic therapies
- Expanding off-label applications in other movement disorders
Competitive Landscape
| Competitor | Product | Formulation | Price Range (per patch) | Market Share | Notes |
|---|---|---|---|---|---|
| UCB Pharma | Neupro (Rotigotine) | Transdermal | $700–$900 | ~60% (U.S.) | First-to-market patch for PD/RLS |
| Generic Manufacturers | Various | Transdermal | $400–$600 | 20–30% | Increasing generics penetration |
| Others | Apomorphine, Dopamine agonists (PRAMAXIN, Requip) | Oral/Invasive | Varies | Remaining | Market shifting towards targeted, non-oral therapies |
Key Market Trends
- Shift toward transdermal systems: Enhanced compliance and stable plasma levels
- Emergence of generics: Price erosion expected but still limited due to patent protections
- Increasing off-label use: Expansion beyond primary indications
- Pricing pressure: Payers push for cost-effective alternatives
Price Trajectory and Projections
Historical Pricing Data (U.S., Approximate)
| Year | Average Price per Patch | Notes |
|---|---|---|
| 2015 | ~$850 | Initially high, with limited competition |
| 2018 | ~$800 | Slight decline due to initial generic entry threats |
| 2022 | ~$750 | Market stabilization; slight downward trend |
Note: These figures exclude rebates and payer discounts, which often reduce net prices.
Price Projection: 2023–2028
| Year | Predicted Average Price per Patch | Rationale |
|---|---|---|
| 2023 | $730–$780 | Slight decline due to increased generic competition, market saturation |
| 2024 | $700–$750 | Initiatives to lower costs, new formulary placements |
| 2025 | $680–$730 | Growing generic share, negotiated discounts |
| 2026 | $650–$700 | Further erosion, potential biosimilar advances |
| 2027 | $620–$670 | Market equilibrium, increased biosimilar entry |
| 2028 | $600–$650 | Price stabilization expected, potential high-value biosimilar approval |
Key Drivers of Price Flattening or Decline:
- Patent expiration (anticipated around 2024-2025)
- Patent challenges and biosimilar development
- Payer negotiations and formularies favoring lower-cost alternatives
Regulatory and Policy Impact
Patent and Exclusivity Timeline
| Patent Expiry | Year | Remarks |
|---|---|---|
| Patents on Rotigotine Delivery | 2024–2025 | Patents set to expire, opening markets for biosimilars/generics |
Healthcare Policy Trends
- Increased value-based pricing: Payers scrutinize cost-effectiveness, temper rise in premium prices
- Prescription drug price reforms: Potential legislative measures aimed at drug affordability [4]
- Accelerated biosimilar approvals: Policy support for biosimilars may reduce prices further
Reimbursement Landscape
| Payer Type | Reimbursement Approach | Impact on Price |
|---|---|---|
| Medicare | Negotiated rates | Lower average price |
| Commercial insurers | Formularies and rebates | Variable, often discount-driven |
Deep-Dive: Factors Influencing Market and Price
| Factor | Impact | Actionable Consideration |
|---|---|---|
| Patent Protection | Supports premium pricing until expiry | Monitor legal challenges |
| Generic Entry | Drives price reduction | Early adoption strategies for generics |
| New Formulations | Can command premium | Investment in innovative delivery systems |
| Regulatory Changes | Affect market access & competition | Scenario planning for policy shifts |
| Off-label Use | Expands market size | Education and awareness campaigns |
Comparative Analysis: Brand vs. Generic Transdermal Dopamine Agonists
| Attribute | Neupro (Brand) | Generic Transdermal | Oral Dopamine Agonists |
|---|---|---|---|
| Price per Patch | ~$700–$900 | $400–$600 | N/A |
| Market Exclusivity | Yes | No (post-patent expiry) | N/A |
| Compliance | High (transdermal) | Similar | Lower (oral side effects) |
| Onset & Duration | Stable, 24-hour | Similar | Variable |
Strategic Insights for Stakeholders
Manufacturers
- Diversify formulation portfolio to extend lifecycle
- Prepare biosimilars and generics pre-patent expiry
- Optimize supply chain to reduce costs
Payers
- Negotiate value-based contracts
- Promote cost-effective off-label alternatives
- Support biosimilar uptake
Clinicians
- Balance efficacy and cost
- Adopt personalized medicine approaches
- Educate patients on compliance benefits
Regulators
- Facilitate timely biosimilar approvals
- Enforce patent laws to prevent abuse
- Promote transparency in pricing
Key Takeaways
- Market Dynamics: The global PD and RLS markets are growing, with Neupro maintaining significant share, yet facing increasing generic competition.
- Price Outlook: Expect modest declines (~10-20%) by 2028 due to patent expiry, biosimilar entry, and payer negotiations.
- Competitive Strategy: Innovating in delivery systems and preparing for biosimilar competition are essential for maintaining market position.
- Regulatory Influence: Patent expiries, legislations, and biosimilar policies will shape future prices.
- Stakeholder Actions: Collaboration among manufacturers, payers, clinicians, and regulators is crucial for market sustainability.
FAQs
-
When is the patent for Neupro expected to expire?
Patent protections are anticipated to expire around 2024–2025, opening pathways for biosimilars and generics. -
How will biosimilar entry affect Neupro’s pricing?
Biosimilar competition generally leads to significant price reductions, potentially 30-50% compared with the brand, depending on market dynamics and uptake. -
Are there any upcoming regulatory approvals that could influence prices?
Yes, biosimilar candidates are in development; regulatory approvals could occur within the next 2–3 years, impacting market competition. -
What strategies can manufacturers adopt to sustain profitability?
Diversification in formulation, early biosimilar development, and leveraging innovative delivery technologies. -
How does payer policy impact the Neupro market?
Payors favor cost-effective alternatives, applying formulary restrictions and rebates that influence net prices and prescribing patterns.
References
[1] Market Data Forecast, 2022
[2] Parkinson’s Foundation, 2022
[3] Grand View Research, 2022
[4] U.S. Congressional Budget Office, 2021
This comprehensive market and price analysis aims to inform stakeholders involved in the strategic planning, manufacturing, and reimbursement of NDC 00074-1069, equipping them with insights to navigate upcoming market shifts effectively.
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