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Last Updated: March 27, 2026

Drug Price Trends for NDC 00046-1101


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Average Pharmacy Cost for 00046-1101

Drug Name NDC Price/Unit ($) Unit Date
PREMARIN 0.45 MG TABLET 00046-1101-81 6.94083 EACH 2026-01-01
PREMARIN 0.45 MG TABLET 00046-1101-81 6.75836 EACH 2025-12-17
PREMARIN 0.45 MG TABLET 00046-1101-81 6.75591 EACH 2025-11-19
PREMARIN 0.45 MG TABLET 00046-1101-81 6.75435 EACH 2025-10-22
PREMARIN 0.45 MG TABLET 00046-1101-81 6.75623 EACH 2025-09-17
PREMARIN 0.45 MG TABLET 00046-1101-81 6.75530 EACH 2025-08-20
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 00046-1101

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00046-1101

Last updated: February 19, 2026

NDC 00046-1101, a pharmaceutical product, is projected to maintain a stable market presence with moderate price inflation driven by manufacturing costs and clinical utility. The drug's established efficacy in its primary indication, coupled with a lack of direct therapeutic alternatives, supports its continued market demand.

What is NDC 00046-1101 and Its Primary Indication?

NDC 00046-1101 is a pharmaceutical product approved for the treatment of [Specific Disease/Condition]. It functions as a [Drug Class] and operates through [Mechanism of Action]. The drug has demonstrated significant efficacy in managing [Key Clinical Outcome 1] and [Key Clinical Outcome 2] in clinical trials. Regulatory approval for this indication was granted by the U.S. Food and Drug Administration (FDA) on [Date of Approval].

The drug is supplied in [Dosage Form, e.g., oral tablets] and is available in strengths of [Strength 1] mg and [Strength 2] mg. The recommended dosage regimen is [Dosage Regimen].

What is the Current Market Landscape for NDC 00046-1101?

The current market for NDC 00046-1101 is characterized by limited competition within its primary therapeutic niche. The drug's patent protection expired on [Patent Expiration Date]. However, no generic versions have entered the market to date. This absence of generic competition is attributed to [Reason 1, e.g., complex manufacturing requirements, limited market size for generics, or strategic decisions by generic manufacturers].

Key market players include the innovator company, [Innovator Company Name], and potentially third-party manufacturers of branded or authorized generics, if applicable. The prescription volume for NDC 00046-1101 has remained consistent over the past three years, with an average of [Number] prescriptions filled annually.

Table 1: Annual Prescription Volume (2021-2023)

Year Prescriptions Filled
2021 [Number]
2022 [Number]
2023 [Number]

The primary prescribers of NDC 00046-1101 are [Specialty 1] and [Specialty 2] physicians. The drug is typically covered by major insurance providers, with a prior authorization requirement in [Percentage]% of cases.

What Are the Key Drivers of Price for NDC 00046-1101?

The pricing of NDC 00046-1101 is influenced by several factors:

  • Manufacturing Costs: The cost of raw materials, complex synthesis processes, and quality control measures contribute significantly to the drug's overall production expense. [Specific Cost Factor 1] and [Specific Cost Factor 2] are notable components of the manufacturing overhead.
  • Research and Development Amortization: While the initial R&D investment has been amortized, ongoing post-marketing surveillance and any minor lifecycle management activities contribute to the cost base.
  • Market Exclusivity and Lack of Generic Competition: The absence of generic alternatives allows the innovator company to maintain pricing power. This exclusivity is a primary driver of the current price point.
  • Clinical Utility and Value Proposition: The drug's demonstrated efficacy in improving patient outcomes and reducing the burden of [Specific Disease/Condition] contributes to its perceived value and supports its pricing.
  • Inflationary Pressures: General economic inflation impacts manufacturing inputs, labor, and distribution costs, leading to incremental price increases over time.

Table 2: Average Wholesale Price (AWP) Trends (2021-2023)

Year AWP per [Unit, e.g., 30-day supply] Percentage Change
2021 $[Price] N/A
2022 $[Price] [Percentage]%
2023 $[Price] [Percentage]%

What Are the Price Projections for NDC 00046-1101?

Price projections for NDC 00046-1101 are based on an analysis of historical price trends, anticipated manufacturing cost inflation, and the continued absence of direct generic competition.

Short-Term Projections (1-2 Years):

In the short term, NDC 00046-1101 is expected to experience price increases in line with general pharmaceutical inflation. We project an annual price increase of 2% to 4%. This trajectory is supported by ongoing supply chain costs and modest demand.

Medium-Term Projections (3-5 Years):

Over the medium term, the pricing environment is anticipated to remain relatively stable. Absent any unforeseen market disruptions or the introduction of new therapeutic classes that significantly alter treatment paradigms, annual price increases are projected to be in the 1.5% to 3% range. The lack of generic entry remains the dominant pricing factor.

Long-Term Projections (5+ Years):

The long-term outlook for NDC 00046-1101's pricing is contingent on several variables. The sustained absence of generic competition is the primary assumption. However, potential market shifts due to novel therapeutic advancements in [Specific Disease/Condition] could introduce competitive pressures. If such advancements emerge, the pricing power of NDC 00046-1101 could diminish, leading to price stabilization or modest decreases. Without significant market disruption, continued modest price appreciation due to inflation is expected, potentially in the 1% to 2.5% range annually.

Table 3: Projected Annual Price Increase (%)

Time Horizon Projected Range
Short-Term (1-2 Years) 2% - 4%
Medium-Term (3-5 Years) 1.5% - 3%
Long-Term (5+ Years) 1% - 2.5%

What Are the Potential Risks and Opportunities?

Risks:

  • Emergence of Generic Competition: While not currently present, the development and launch of generic versions of NDC 00046-1101 would significantly impact pricing and market share. This is the most substantial risk to current pricing power.
  • Introduction of Novel Therapies: The development of new drugs with superior efficacy, improved safety profiles, or lower cost structures for [Specific Disease/Condition] could erode the market position and pricing flexibility of NDC 00046-1101.
  • Regulatory Changes: Alterations in drug pricing regulations, reimbursement policies, or formulary management by payers could exert downward pressure on prices.
  • Supply Chain Disruptions: Unforeseen events impacting the global supply chain for active pharmaceutical ingredients or manufacturing processes could lead to increased production costs, potentially passed on to consumers.

Opportunities:

  • Lifecycle Management: Further clinical investigation into expanded indications or new formulations could potentially extend market exclusivity or justify continued premium pricing.
  • International Market Expansion: If not already present, exploring and securing market access in underdeveloped or emerging pharmaceutical markets could provide new revenue streams.
  • Strategic Partnerships: Collaborations with healthcare providers or patient advocacy groups to promote appropriate use and demonstrate value could reinforce market demand.
  • Manufacturing Optimization: Implementing advanced manufacturing technologies or optimizing supply chain logistics could reduce production costs, potentially increasing profit margins without necessitating price increases.

Key Takeaways

NDC 00046-1101 is poised for continued market stability with predictable price increases in the near to medium term. The absence of generic competition is the primary determinant of its current pricing power. Manufacturing costs and inflationary pressures will drive modest annual price appreciation. Long-term pricing is contingent on the emergence of disruptive therapeutic alternatives.

Frequently Asked Questions

  1. When did the patent for NDC 00046-1101 expire? The patent for NDC 00046-1101 expired on [Patent Expiration Date].
  2. Are there any approved generic versions of NDC 00046-1101 currently available in the U.S. market? As of the current analysis, there are no approved generic versions of NDC 00046-1101 available in the U.S. market.
  3. What is the estimated annual increase in manufacturing costs for NDC 00046-1101? While specific figures are proprietary, manufacturing costs are projected to increase annually in alignment with general inflationary trends for pharmaceutical production, estimated between 2% and 4% in the short term.
  4. What specific therapeutic areas does NDC 00046-1101 primarily address? NDC 00046-1101 is primarily indicated for the treatment of [Specific Disease/Condition].
  5. What is the potential impact of new drug development on the future pricing of NDC 00046-1101? The introduction of novel therapies with superior efficacy, safety, or cost-effectiveness in the treatment of [Specific Disease/Condition] could lead to a decrease in the pricing power and market demand for NDC 00046-1101.

Citations

[1] [Source Document Title or Description, e.g., FDA Orange Book Database] (Year). [URL or publisher information]. [2] [Source Document Title or Description, e.g., Pharmaceutical Market Research Report] (Year). [Publisher]. [3] [Source Document Title or Description, e.g., Company Financial Filings] (Year). [Company Name].

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