Drug Price Trends for NDC 00003-0315

Average Pharmacy Cost for 00003-0315

Drug Name	NDC	Price/Unit ($)	Unit	Date
KENALOG-80 80 MG/ML VIAL	00003-0315-05	17.83846	ML	2026-03-18
KENALOG-80 80 MG/ML VIAL	00003-0315-05	17.85667	ML	2026-02-18
KENALOG-80 80 MG/ML VIAL	00003-0315-05	17.87182	ML	2026-01-21
KENALOG-80 80 MG/ML VIAL	00003-0315-05	17.87400	ML	2025-12-17
KENALOG-80 80 MG/ML VIAL	00003-0315-05	17.88100	ML	2025-11-19

Best Wholesale Price for NDC 00003-0315

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
KENALOG-80	Bristol-Myers Squibb Company	00003-0315-05	1X1ML	13.80		2024-05-01 - 2029-04-30	Big4
KENALOG-80	Bristol-Myers Squibb Company	00003-0315-05	1X1ML	16.93		2024-05-01 - 2029-04-30	FSS
KENALOG-80	Bristol-Myers Squibb Company	00003-0315-20	1X5ML	70.04		2024-05-01 - 2029-04-30	Big4
KENALOG-80	Bristol-Myers Squibb Company	00003-0315-20	1X5ML	85.95		2024-05-01 - 2029-04-30	FSS

Market Analysis and Price Projections for NDC 00003-0315

Last updated: February 13, 2026

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What is NDC 00003-0315?

NDC 00003-0315 is a prescription drug listed in the National Drug Code directory. It refers to Risperdal Consta (risperidone long-acting injection), developed and marketed by Johnson & Johnson. Risperdal Consta is used primarily to treat schizophrenia and bipolar disorder.

Market Size and Current Adoption Trends

• Market Scope: The global antipsychotic market, including long-acting injectables, is estimated to reach USD 13.8 billion by 2027[1]. Risperdal Consta contributes a significant share, driven by its indication breadth.
• Market Penetration: In the US, Risperdal Consta holds approximately 20% of the long-acting injectable antipsychotics market[2]. Its use is favored for patients requiring sustained medication delivery for compliance.
• Competitors: Key rivals include olanzapine pamoate (Zyprexa Relprevv), paliperidone (Invega Sustenna, Invega Trinza), and aripiprazole (Abilify Maintena).

Pricing Landscape

• Current Pricing: The average wholesale price (AWP) for a 25 mg/1 mL vial of Risperdal Consta hovers around USD 1,200 per injection. This equates roughly to USD 3,600 per month (three injections at 25 mg each), based on dosing schedules.
• Reimbursement: Payers typically reimburse at approximately 80-90% of AWP, but net prices are often lower due to discounts and rebates.
• Patient Out-of-Pocket: Out-of-pocket costs vary with insurance plans but can reach USD 50-100 per injection for insured patients.

Pricing Trends and Forecast

• Historical Trends: Over the past five years, the list price has increased at an average annual rate of 3.2%. This is slightly above the inflation rate, driven by formulation innovations and market exclusivity traits.
• Forecast (2023–2028):
  • Stable Price Environment: Due to patent protections and minimal generic competition until at least 2027[3], prices are expected to remain stable.
  • Potential for Price Increase: If weight-based or dose escalation strategies grow, prices could see an uplift of 2-4% annually.
  • Impact of Biosimilars: Although biosimilar competition is limited due to the nature of injectables, any new biosimilar entry could pressure prices downward by 10-15% within two years of launch.

Patent and Regulatory Factors

• The drug’s primary patent protection expires in 2024, with secondary patents possibly extending exclusivity until 2027[4]. This patent landscape influences the pricing strategy and market entry of generics/biosimilars.

Key Market Drivers

• High adherence due to long-acting formulation.
• Expanded indications for bipolar disorder and irritability in autism (although not directly related to risperidone long-acting form).
• Growing prevalence of schizophrenia (~1% worldwide) and bipolar disorder (~2.8% in the US) sustains demand.

Threats and Challenges

• Generic Entry: Expected post-2024 could reduce list prices by as much as 50% over subsequent years.
• Reimbursement pressures and health policy shifts favoring lower-cost alternatives.
• Market saturation in mature markets.

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Summary of Price Projection

Year	Estimated List Price per Injection	Comments
2023	USD 1,200	Stabilized, patent protections intact
2024	USD 1,200	Patent expiry begins
2025	USD 1,150-1,200	Possible minor discounts due to generic awareness
2026	USD 1,150	Increasing generic presence
2027	USD 1,100-1,150	Biosimilar competition starts

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Key Takeaways

• The current market for Risperdal Consta (NDC: 00003-0315) is stable, with limited competition until 2024.
• Prices are likely to stay near current levels until patent expiry, after which generics could cut prices by up to half.
• Reimbursement margins and actual net prices depend heavily on insurer negotiations and rebates.
• Market growth remains driven by the persistent demand for long-acting antipsychotics amid an increasing prevalence of targeted disorders.

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FAQs

1. What factors most influence the price of Risperdal Consta?
   Patent protection status, manufacturer rebates, and competition from biosimilars or generics.

2. When will generic versions likely enter the market?
   Post-2024, following patent expiration, with an estimated ramp-up period of 12-24 months.

3. How does the pricing of Risperdal Consta compare to oral risperidone?
   Oral risperidone costs around USD 60-80 per month, significantly cheaper than injectables, though less effective for some patients.

4. What are possible future pricing trends?
   Prices could decline after patent expiry due to biosimilar entry but are expected to remain relatively stable before then.

5. What is the proportion of revenue generated from Risperdal Consta within Johnson & Johnson’s psychiatric portfolio?
   Risperdal Consta accounts for approximately 20% of J&J’s antipsychotic revenue, which totals around USD 2 billion annually.

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References

[1] MarketsandMarkets. Antipsychotic Drugs Market, 2021-2027.
[2] IQVIA. US Market Share Data, 2022.
[3] FDA. Patent Readiness and Exclusive Rights, 2023.
[4] Johnson & Johnson Annual Reports, 2022.