Drug Price Trends for TRANYLCYPROMINE SULF

Average Pharmacy Cost for TRANYLCYPROMINE SULF

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
TRANYLCYPROMINE SULF 10 MG TAB	70954-0538-10	0.72608	EACH	2025-05-21
TRANYLCYPROMINE SULF 10 MG TAB	00591-5590-01	0.72608	EACH	2025-05-21
TRANYLCYPROMINE SULF 10 MG TAB	43547-0655-10	0.72608	EACH	2025-05-21
TRANYLCYPROMINE SULF 10 MG TAB	64380-0176-01	0.72608	EACH	2025-05-21
TRANYLCYPROMINE SULF 10 MG TAB	70954-0538-10	0.72001	EACH	2025-04-23
TRANYLCYPROMINE SULF 10 MG TAB	00591-5590-01	0.72001	EACH	2025-04-23
TRANYLCYPROMINE SULF 10 MG TAB	64380-0176-01	0.72001	EACH	2025-04-23

Market Analysis and Price Projections for Tranylcypromine Sulfate

Introduction to Tranylcypromine Sulfate

Tranylcypromine sulfate, commonly known by its brand name Parnate, is a monoamine oxidase inhibitor (MAOI) used primarily in the treatment of severe, treatment-resistant depressive disorders, especially those with an anxiety component. It is also effective in treating other mood and anxiety disorders such as obsessive-compulsive disorder and panic disorder[4].

Market Overview of Antidepressants

The US antidepressant market is significant and growing. As of 2022, the market was valued at $6.9 billion and is projected to reach $9.37 billion by 2030, with a compound annual growth rate (CAGR) of 3.9%[3].

Market Segmentation and Growth Drivers

Drug Class

The antidepressant market is segmented by drug class, with MAOIs like tranylcypromine being one of the categories. Although selective serotonin reuptake inhibitors (SSRIs) hold the largest market share, the demand for MAOIs remains steady due to their efficacy in treating specific types of depression[3].

Indication

Major depressive disorder is the primary indication for tranylcypromine, and this segment is expected to continue leading the market due to the high prevalence of major depressive disorders. Initiatives by governments and private organizations to develop and promote treatments for mental health disorders also drive this segment[3].

Market Growth Drivers

The rising incidence of depression and other mental health conditions, along with increasing public awareness and the development of new antidepressant drugs, are key drivers of the market. The expansion of pharmaceutical companies' product lines and the introduction of customized and combination medicines also contribute to market growth[3].

Pricing and Cost Analysis

Brand vs. Generic Pricing

Tranylcypromine is available in both brand (Parnate) and generic forms. The brand version, Parnate, is significantly more expensive, with a cost of around $1,038 for a supply of 100 tablets. In contrast, the generic version of tranylcypromine can be obtained for as low as $97.50 for 100 tablets[2][5].

Cost Savings and Assistance Programs

To make tranylcypromine more affordable, various cost-saving measures are available, including printable coupons, rebates, copay cards, and patient assistance programs. For example, the Drugs.com discount card can save patients up to 80% on prescription medications, and specific savings cards can reduce the cost to $0 per 30-day supply for eligible commercially insured patients[2][5].

Market Restraints

Generic Competition

The availability of generic versions of tranylcypromine can affect the overall revenue of the brand name product. Generic medications are generally cheaper, which can lead to a shift in market share from brand to generic products[3].

Regulatory Standards

Strict regulatory standards for antidepressant drug approval can delay the introduction of new medications, affecting market growth. Clinical trials are lengthy and expensive, and rising regulatory scrutiny adds to these challenges[3].

Side Effects and Compliance

Antidepressant side effects, such as weight gain, nausea, and dizziness, can impact patient compliance and treatment adherence. This can also influence the market as patients may seek alternative treatments with fewer side effects[3].

Future Projections

Market Size and Growth

Given the growing demand for antidepressant medications and the specific niche that tranylcypromine fills in treating severe and treatment-resistant depression, the market for this drug is expected to remain stable. The overall antidepressant market is projected to grow, driven by the increasing prevalence of mental health disorders and advancements in treatment options[3].

Pricing Trends

The pricing of tranylcypromine is likely to remain competitive, with generic versions continuing to offer a cost-effective alternative to the brand name product. However, the brand name may retain a premium due to its established reputation and patient loyalty. Cost-saving programs and discounts will continue to play a crucial role in making the drug more accessible to patients[2][5].

Key Takeaways

• Market Growth: The US antidepressant market, including MAOIs like tranylcypromine, is expected to grow at a CAGR of 3.9% from 2022 to 2030.
• Pricing: Generic tranylcypromine is significantly cheaper than the brand name Parnate, with costs ranging from $97.50 to $1,038 for 100 tablets.
• Market Drivers: Rising incidence of depression, public awareness, and development of new treatments drive the market.
• Market Restraints: Generic competition, regulatory standards, and side effects impact market dynamics.
• Future Projections: The market for tranylcypromine is expected to remain stable, with a focus on cost-saving measures and competitive pricing.

FAQs

1. What is tranylcypromine used for? Tranylcypromine is used to treat severe, treatment-resistant depressive disorders, including atypical depression, and other mood and anxiety disorders such as obsessive-compulsive disorder and panic disorder[4].

2. How does tranylcypromine work? Tranylcypromine acts as a nonselective and irreversible inhibitor of monoamine oxidase, increasing the availability of monoamines like serotonin, norepinephrine, and dopamine[4].

3. What is the difference between brand and generic tranylcypromine? The brand name, Parnate, is significantly more expensive than the generic version of tranylcypromine. Generic versions can cost as low as $97.50 for 100 tablets, while Parnate costs around $1,038 for the same quantity[2][5].

4. Are there any cost-saving programs available for tranylcypromine? Yes, various cost-saving measures are available, including printable coupons, rebates, copay cards, and patient assistance programs that can reduce the cost to $0 per 30-day supply for eligible patients[2][5].

5. What are the potential side effects of tranylcypromine? Common side effects include weight gain, nausea, and dizziness, which can impact patient compliance and treatment adherence[3].

Sources

1. Public Assessment Report Scientific discussion Tranylcypromine Tiofarma 10 mg, coated tablets - Medicines Evaluation Board (MEB) of the Netherlands.
2. Tranylcypromine Prices, Coupons, Copay Cards & Patient Assistance - Drugs.com.
3. US Anti-Depressants Drugs Market Report 2022 to 2030 - Insights10.
4. Tranylcypromine - Wikipedia.
5. Parnate Prices, Coupons, Copay Cards & Patient Assistance - Drugs.com.

Last updated: 2024-12-31