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Last Updated: April 19, 2025

Drug Price Trends for TRAMADOL HCL


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Drug Price Trends for TRAMADOL HCL

Average Pharmacy Cost for TRAMADOL HCL

These are average pharmacy acquisition costs (net of discounts) from a US national survey
Drug Name NDC Price/Unit ($) Unit Date
TRAMADOL HCL 50 MG TABLET 00093-0058-01 0.02594 EACH 2025-03-19
TRAMADOL HCL 50 MG TABLET 00093-0058-05 0.02594 EACH 2025-03-19
TRAMADOL HCL 25 MG TABLET 72888-0162-30 3.10446 EACH 2025-03-19
TRAMADOL HCL 50 MG TABLET 00093-3301-01 0.02594 EACH 2025-03-19
TRAMADOL HCL ER 300 MG TABLET 68180-0699-06 2.44842 EACH 2025-03-19
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for TRAMADOL HCL

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available to any customer under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Unit Dates Price Type
TRAMADOL HCL 50MG TAB AvKare, LLC 65162-0627-10 100 10.49 0.10490 EACH 2023-06-15 - 2028-06-14 FSS
TRAMADOL HCL 50MG TAB AvKare, LLC 65162-0627-11 1000 55.61 0.05561 EACH 2023-06-15 - 2028-06-14 FSS
TRAMADOL HCL 50MG TAB AvKare, LLC 65162-0627-50 500 34.22 0.06844 EACH 2023-06-15 - 2028-06-14 FSS
SEGLENTIS Kowa Pharmaceuticals America, Inc. 66869-0564-35 35 113.87 3.25343 EACH 2024-01-01 - 2028-03-31 FSS
SEGLENTIS Kowa Pharmaceuticals America, Inc. 66869-0564-90 90 272.15 3.02389 EACH 2024-01-01 - 2028-03-31 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Unit >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Tramadol HCL Market Analysis and Price Projections

Market Overview

Tramadol HCL, a potent opioid analgesic, is widely used for managing moderate to moderately severe pain in adults. The global market for Tramadol HCL is experiencing significant growth driven by several key factors.

Market Size and Forecast

As of 2023, the Tramadol HCL market was valued at approximately USD 4.24 billion[4].

  • The market is projected to grow at a Compound Annual Growth Rate (CAGR) of 6.86% from 2024 to 2030, reaching nearly USD 6.75 billion by 2030[4].
  • Another estimate suggests that the market will increase by USD 1.4 billion at a CAGR of 5.6% from 2023 to 2028, with the market size estimated to be around USD 2.7 billion in 2023[3].

Drivers of Market Growth

Increasing Prevalence of Chronic Pain

The rising prevalence of chronic pain conditions, particularly among the aging population, is a major driver of the Tramadol HCL market. Chronic pain is a significant health issue globally, and the demand for effective pain management drugs is increasing accordingly[2].

Expanding Geriatric Population

The growing geriatric population is another key factor. Older adults are more prone to chronic pain conditions, which increases the demand for tramadol and other pain management medications[2].

Advancements in Drug Formulations

Innovations in drug delivery systems, such as extended-release formulations and combination products (e.g., tramadol-acetaminophen), are enhancing the market's growth. These advancements improve patient compliance and efficacy, making tramadol more appealing to both healthcare providers and patients[4].

Regional Analysis

Europe

Europe is expected to maintain a significant share in the global Tramadol HCL market due to high healthcare expenditure, favorable government initiatives for opioid substitution therapy, and a high prevalence of chronic pain conditions[2].

Asia Pacific

The Asia Pacific region is witnessing rapid growth, driven by improving healthcare infrastructure, rising disposable incomes, and increasing awareness about pain management. Countries like China and India offer substantial growth opportunities due to their large and diverse patient populations[4].

North America

North America is also a significant market, with major players like Pfizer, Johnson & Johnson, and Teva Pharmaceuticals leveraging their extensive distribution networks and strong R&D capabilities to maintain a competitive edge[4].

Market Segmentation

By Type

The market is segmented by type, including intramuscular injection, oral, and rectal administration. The intramuscular injection segment accounted for a noticeable share of the global Tramadol HCL market and is projected to experience significant growth in the near future[1].

By Application

The hospital segment is expected to expand at a significant CAGR, retaining its position throughout the forecast period. Other applications include clinics and medical centers[3].

By Distribution Channel

The market is also segmented by distribution channels such as hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacy segment is a major contributor due to the frequent prescription and use of tramadol in hospital settings[4].

Competitive Landscape

Key players in the Tramadol HCL market include GrĂ¼nenthal GmbH, Mundipharma, Labopharm, Pfizer Inc., Johnson & Johnson, Teva Pharmaceuticals, and GSK plc. These companies are focusing on strategy building, product portfolio expansion, and leveraging their strong R&D capabilities to maintain market dominance[1][3][4].

Price Projections and Cost Analysis

Cost Without Insurance

Without insurance, the cash price for 30, 50 mg oral tablets of immediate-release tramadol HCL is approximately $31, which works out to about $1 per tablet[5].

Extended-Release Formulations

Extended-release tramadol costs around $150 for 30, 100 mg tablets, representing a 30-day supply. This is significantly higher than the immediate-release version but provides longer-lasting pain relief[5].

Cost Reduction Strategies

Using savings cards, shopping around for lower prices, switching to other opioid or non-opioid analgesics, and exploring eligibility for Medicaid are strategies to reduce the cost of tramadol HCL[5].

Challenges and Restraints

Regulatory Frameworks

Stringent regulatory frameworks, particularly in the United States, closely monitor tramadol due to its potential for abuse and dependence. This can impact market growth and the availability of the drug in certain regions[4].

Consumer Behavior and Awareness

Consumer awareness about opioid substitution therapy and the risks associated with opioid use can influence market dynamics. Educating consumers and healthcare providers about the safe use of tramadol is crucial for sustained market growth[1].

"Tramadol is an opioid analgesic, a type of narcotic medicine that is approved to treat moderate to moderately severe pain in adults. It is available under the brand names Ultram, Ultram ER, Conzip, and also as generics."[4]

Key Takeaways

  • The Tramadol HCL market is projected to grow significantly, driven by the increasing prevalence of chronic pain and advancements in drug formulations.
  • Europe and the Asia Pacific region are key markets, with Europe maintaining a major stake due to high healthcare expenditure and favorable government initiatives.
  • The hospital segment is expected to expand significantly, and intramuscular injection is a growing segment.
  • Major players are focusing on expanding their product portfolios and leveraging strong R&D capabilities.
  • Cost reduction strategies such as savings cards and exploring Medicaid eligibility can help make tramadol more affordable.

Frequently Asked Questions

1. What is the projected market size of the Tramadol HCL market by 2030?

The Tramadol HCL market is expected to reach nearly USD 6.75 billion by 2030, growing at a CAGR of 6.86% from 2024 to 2030[4].

2. Which regions are expected to drive the growth of the Tramadol HCL market?

Europe and the Asia Pacific region are expected to be the key drivers of the Tramadol HCL market growth. Europe will maintain a significant share due to high healthcare expenditure and favorable government initiatives, while the Asia Pacific region will grow rapidly due to improving healthcare infrastructure and increasing awareness about pain management[2][4].

3. What are the main segments of the Tramadol HCL market?

The market is segmented by type (intramuscular injection, oral, rectal administration), application (hospital, clinic, medical center), and distribution channel (hospital pharmacy, retail pharmacy, online pharmacy)[1][3][4].

4. How much does tramadol HCL cost without insurance?

Without insurance, the cash price for 30, 50 mg oral tablets of immediate-release tramadol HCL is approximately $31, or about $1 per tablet[5].

5. What are the key challenges facing the Tramadol HCL market?

The key challenges include stringent regulatory frameworks due to the potential for abuse and dependence, and the need for consumer education about safe use and opioid substitution therapy[4].

Sources:

  1. Cognitivemarketresearch.com - Global Tramadol HCL Market Report 2024 Edition
  2. Verifiedmarketresearch.com - Tramadol Drug Market Size, Share, Trends, Growth And Forecast
  3. Einpresswire.com - Tramadol Hcl Market Comprehensive Study by Key Players Grnenthal GmbH, Mundipharma, Labopharm
  4. Stellarmr.com - Tramadol Market: Global Industry Analysis and Forecast (2024-2030)
  5. Singlecare.com - How much is tramadol HCL (Qdolo) without insurance?

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