Drug Price Trends for ATENOLOL-CHLORTHALIDONE

Average Pharmacy Cost for ATENOLOL-CHLORTHALIDONE

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
ATENOLOL-CHLORTHALIDONE 100-25	16714-0937-01	0.30748	EACH	2024-12-18
ATENOLOL-CHLORTHALIDONE 100-25	70710-1168-01	0.30748	EACH	2024-12-18
ATENOLOL-CHLORTHALIDONE 100-25	70954-0391-10	0.30748	EACH	2024-12-18
ATENOLOL-CHLORTHALIDONE 100-25	29300-0401-01	0.30748	EACH	2024-12-18
ATENOLOL-CHLORTHALIDONE 50-25	70954-0390-10	0.25401	EACH	2024-12-18

Atenolol-Chlorthalidone Market Analysis and Price Projections

Market Overview

The atenolol-chlorthalidone market is a significant segment within the broader antihypertensive drugs market. This combination drug, often marketed under brand names such as Tenoretic, is widely used to treat high blood pressure (hypertension) and other cardiovascular conditions.

Market Size and Growth

The global atenolol market, which includes atenolol-chlorthalidone combinations, is projected to experience substantial growth. As of 2023, the market size was valued at approximately USD 11.59 billion and is expected to reach USD 22.97 billion by 2036, growing at a compound annual growth rate (CAGR) of around 5.4% during the forecast period of 2024-2036[1][3].

Growth Drivers

Several factors are driving the growth of the atenolol-chlorthalidone market:

Increasing Prevalence of Hypertension

The global prevalence of hypertension is a major driver. According to the World Health Organization (WHO), an estimated 1.28 billion people aged 30-79 years have hypertension, with the majority residing in low- and middle-income countries[1].

Aging Population

The significant rise in the aged population worldwide is another key factor. The global population of people aged 60 and above is projected to increase from 1 billion in 2020 to 1.4 billion by 2030 and further to 2.1 billion by 2050[1].

Poor Lifestyle and Dietary Habits

Poor lifestyle choices and dietary habits among the general population are also contributing to the growing demand for antihypertensive drugs like atenolol-chlorthalidone[1].

Growing Prevalence of Cardiovascular Diseases

The increasing prevalence of cardiovascular diseases, including coronary heart disease, arrhythmia, and angina, is driving the demand for atenolol-chlorthalidone. For instance, in the U.S., the prevalence of coronary heart disease among adults aged 18 and over stood at 4.6% in 2020 and slightly increased to 4.9% in 2021[3].

Market Segmentation

By Application

Atenolol-chlorthalidone is primarily used for treating hypertension, but it also finds applications in managing angina, arrhythmia, and other cardiovascular conditions[1][3].

By Distribution Channel

The market is segmented by distribution channels into hospital pharmacies, drug stores, online pharmacies, and others. Hospital pharmacies are expected to hold a significant share, around 49% by 2036, due to the rising patient pool and increasing number of hospitals. Online pharmacies are also expected to witness impressive growth due to rising awareness and internet penetration[1].

Regional Analysis

North America

The North American market is projected to hold the largest share, approximately 40% by 2036, driven by the high prevalence of cardiac diseases and hypertension in the region. For example, in the U.S., 116 million individuals have hypertension, and hypertension-related deaths were around 0.5 million in 2019[1].

Europe

The European market is expected to hold a noteworthy share, around 17% by 2036, due to the high incidence of cardiovascular diseases. Every year, more than 1.6 million deaths in the European Union are attributed to cardiovascular diseases[1].

APAC

The Asia-Pacific region is also expected to see significant growth due to the large population and increasing awareness about hypertension and cardiovascular diseases.

Price Projections

Current Pricing

The cost of atenolol-chlorthalidone varies based on the dosage and quantity. For instance, a 30-day supply of 50 mg-25 mg oral tablets can cost around $26.45, while a 100 mg-25 mg oral tablet for 100 tablets can cost approximately $88.87[2][5].

Generic Versions

Generic versions of atenolol-chlorthalidone are available, which can significantly reduce the cost. For example, Unichem Laboratories Limited has obtained ANDA authorization for its generic version of atenolol and chlorthalidone tablets[1].

Challenges and Restraints

Side Effects and Complications

Atenolol-chlorthalidone can have several side effects, including new or worsening heart failure, bradycardia, electrolyte changes, and severe skin reactions like Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). These complications can restrain market growth if not managed properly[4].

Regulatory and Economic Factors

Factors such as high inflation, the Ukraine-Russia war, and the COVID-19 pandemic can impact the market by disrupting supply chains and affecting healthcare expenditure[3].

Key Takeaways

• The atenolol-chlorthalidone market is expected to grow significantly due to the increasing prevalence of hypertension and cardiovascular diseases.
• The market is driven by factors such as the aging population, poor lifestyle choices, and the growing awareness of hypertension complexities.
• North America and Europe are expected to hold major market shares due to high disease prevalence and advanced healthcare infrastructure.
• Generic versions and online pharmacies are expected to play a crucial role in making the drug more accessible and affordable.

FAQs

1. What is atenolol-chlorthalidone used for? Atenolol-chlorthalidone is commonly used to treat high blood pressure (hypertension) and can also be used for conditions like angina and arrhythmia[4].

2. How does atenolol-chlorthalidone work? Atenolol-chlorthalidone works by blocking beta-1 receptors in the heart, reducing heart rate, and increasing urine production to lower blood pressure[4].

3. What are the potential side effects of atenolol-chlorthalidone? Potential side effects include new or worsening heart failure, bradycardia, electrolyte changes, and severe skin reactions like Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)[4].

4. How much does atenolol-chlorthalidone cost? The cost varies, but a 30-day supply of 50 mg-25 mg oral tablets can cost around $26.45, and a 100 mg-25 mg oral tablet for 100 tablets can cost approximately $88.87[2][5].

5. Are generic versions of atenolol-chlorthalidone available? Yes, generic versions of atenolol-chlorthalidone are available, which can be more affordable than the brand-name versions[1][5].

Sources

1. Research Nester: Atenolol Market Size & Share, Growth Forecasts 2025-2037
2. Drugs.com: Atenolol/chlorthalidone Prices, Coupons, Copay Cards & Patient Assistance
3. The Business Research Company: Atenolol Global Market Report 2024
4. WebMD: Atenolol/Chlorthalidone: Uses, Side Effects, Interactions
5. Drugs.com: Tenoretic 100 Prices, Coupons, Copay Cards & Patient Assistance