Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo
Completed
National Institute on Drug Abuse (NIDA)
Phase 2
2003-09-01
Dextro-amphetamine sulfate is a central nervous system stimulant that increases the release
of the neurotransmitter dopamine in the brain. The purpose of this study is to further
examine dose ranges of dextro-amphetamine sulfate as a treatment for cocaine dependence.
Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo
Completed
The University of Texas Health Science Center, Houston
Phase 2
2003-09-01
Dextro-amphetamine sulfate is a central nervous system stimulant that increases the release
of the neurotransmitter dopamine in the brain. The purpose of this study is to further
examine dose ranges of dextro-amphetamine sulfate as a treatment for cocaine dependence.
Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
Completed
New River Pharmaceuticals
Phase 1/Phase 2
2006-01-01
This research is being done to evaluate if NRP104 is a safe drug. The other purpose is to
learn if NRP104 produces a high and any other effects like amphetamine and other stimulant
drugs that are abused. This information will give some indication if NRP104 can be abused.
NRP104 is an investigational drug. This means that it has not been approved by the U.S. Food
and Drug Administration (FDA). Healthy people, between the ages of 18 and 55 with histories
of substance abuse that include stimulant drugs, may join. Amphetamines are drugs that are
used most often to treat attention deficit hyperactivity disorder (ADHD) in children, to
treat narcolepsy (excessive sleepiness) and for weight loss.
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
Completed
National Institute of Neurological Disorders and Stroke (NINDS)
N/A
2007-04-01
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to
improve learning of movement skills and the adaptation processes in patients after stroke.
Once investigators have determined the improving effect of TMS and the drugs on learning of
movement skills, the study team may be able to provide information that improves
rehabilitative treatment and helps to improve recovery after stroke.
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