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Last Updated: November 26, 2020

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CLINICAL TRIALS PROFILE FOR ZORTRESS

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All Clinical Trials for Zortress

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00419159 Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy Completed Novartis Pharmaceuticals Phase 2 2006-12-01 To assess the safety and efficacy of weekly (70 mg per week) and daily (10 mg per day) everolimus in patients with metastatic colorectal cancer whose cancer has progressed despite prior treatment with targeted therapy and chemotherapy.
NCT00622869 Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients Completed Novartis Pharmaceuticals Phase 3 2008-01-01 This trial was designed to address important issues that impact recipients of liver allografts as well as clinicians, ie, renal function, reduction or discontinuation of tacrolimus early post-transplantation, and progression rate of fibrosis in hepatitis C virus (HCV) positive patients.
NCT00651482 Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus) Terminated Genentech, Inc. Phase 2 2008-08-01 To determine the safety and efficacy of the combination of bevacizumab and everolimus (RAD001) for the treatment of metastatic renal cell cancer
NCT00651482 Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus) Terminated Novartis Phase 2 2008-08-01 To determine the safety and efficacy of the combination of bevacizumab and everolimus (RAD001) for the treatment of metastatic renal cell cancer
NCT00651482 Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus) Terminated Sandy Srinivas Phase 2 2008-08-01 To determine the safety and efficacy of the combination of bevacizumab and everolimus (RAD001) for the treatment of metastatic renal cell cancer
NCT01051570 Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel Completed National Cancer Institute (NCI) Phase 2 2010-02-01 RATIONALE: Drugs used in chemotherapy, such as carboplatin and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving carboplatin together with everolimus and prednisone may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving carboplatin together with everolimus and prednisone works in treating patients with metastatic prostate cancer that progressed after docetaxel.
NCT01051570 Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel Completed Barbara Ann Karmanos Cancer Institute Phase 2 2010-02-01 RATIONALE: Drugs used in chemotherapy, such as carboplatin and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving carboplatin together with everolimus and prednisone may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving carboplatin together with everolimus and prednisone works in treating patients with metastatic prostate cancer that progressed after docetaxel.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Zortress

Condition Name

Condition Name for Zortress
Intervention Trials
Breast Cancer 3
Liver Transplantation 3
Renal Transplant 3
Endometrial Cancer 2
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Condition MeSH

Condition MeSH for Zortress
Intervention Trials
Carcinoma 7
Neoplasms 6
Renal Insufficiency 5
Breast Neoplasms 4
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Clinical Trial Locations for Zortress

Trials by Country

Trials by Country for Zortress
Location Trials
United States 208
Italy 11
Canada 8
Spain 6
Brazil 4
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Trials by US State

Trials by US State for Zortress
Location Trials
Texas 17
California 13
Ohio 8
Illinois 8
New York 8
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Clinical Trial Progress for Zortress

Clinical Trial Phase

Clinical Trial Phase for Zortress
Clinical Trial Phase Trials
Phase 4 7
Phase 3 7
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Zortress
Clinical Trial Phase Trials
Recruiting 20
Not yet recruiting 10
Active, not recruiting 9
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Clinical Trial Sponsors for Zortress

Sponsor Name

Sponsor Name for Zortress
Sponsor Trials
M.D. Anderson Cancer Center 13
Novartis Pharmaceuticals 12
National Cancer Institute (NCI) 11
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Sponsor Type

Sponsor Type for Zortress
Sponsor Trials
Other 52
Industry 30
NIH 13
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