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Last Updated: March 5, 2024

CLINICAL TRIALS PROFILE FOR ZOLADEX


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All Clinical Trials for Zoladex

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002597 ↗ Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer Completed National Cancer Institute (NCI) Phase 3 1994-10-01 RATIONALE: Radiation therapy (RT) uses high-energy x-rays to damage tumor cells. Androgens can stimulate the growth of prostate cancer cells. Hormone therapy using flutamide, goserelin, and leuprolide may fight prostate cancer by reducing the production of androgens. It is not yet known which regimen of antiandrogen therapy is most effective for prostate cancer. PURPOSE: Randomized phase III trial to study the effectiveness of radiation therapy with or without antiandrogen therapy in treating patients who have stage I or stage II prostate cancer.
NCT00002597 ↗ Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer Completed Radiation Therapy Oncology Group Phase 3 1994-10-01 RATIONALE: Radiation therapy (RT) uses high-energy x-rays to damage tumor cells. Androgens can stimulate the growth of prostate cancer cells. Hormone therapy using flutamide, goserelin, and leuprolide may fight prostate cancer by reducing the production of androgens. It is not yet known which regimen of antiandrogen therapy is most effective for prostate cancer. PURPOSE: Randomized phase III trial to study the effectiveness of radiation therapy with or without antiandrogen therapy in treating patients who have stage I or stage II prostate cancer.
NCT00003645 ↗ Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Terminated AstraZeneca Phase 3 1999-06-14 RATIONALE: Testosterone can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of testosterone. It is not yet known whether receiving leuprolide and flutamide is more effective than receiving no further therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of hormone therapy in treating patients who have stage I or stage II prostate cancer that is at high risk of recurrence and who have already undergone surgery.
NCT00003645 ↗ Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Terminated Eastern Cooperative Oncology Group Phase 3 1999-06-14 RATIONALE: Testosterone can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of testosterone. It is not yet known whether receiving leuprolide and flutamide is more effective than receiving no further therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of hormone therapy in treating patients who have stage I or stage II prostate cancer that is at high risk of recurrence and who have already undergone surgery.
NCT00003645 ↗ Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Terminated National Cancer Institute (NCI) Phase 3 1999-06-14 RATIONALE: Testosterone can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of testosterone. It is not yet known whether receiving leuprolide and flutamide is more effective than receiving no further therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of hormone therapy in treating patients who have stage I or stage II prostate cancer that is at high risk of recurrence and who have already undergone surgery.
NCT00003645 ↗ Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Terminated M.D. Anderson Cancer Center Phase 3 1999-06-14 RATIONALE: Testosterone can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of testosterone. It is not yet known whether receiving leuprolide and flutamide is more effective than receiving no further therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of hormone therapy in treating patients who have stage I or stage II prostate cancer that is at high risk of recurrence and who have already undergone surgery.
NCT00003915 ↗ Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment Completed Dana-Farber Cancer Institute Phase 2 2004-03-01 The purpose of this study is to see if the combination of chemotherapy drugs and drugs to suppress testosterone (hormone therapy) is effective in controlling early prostate cancer. This study will attempt to: - stop or slow the growth of disease - gain information about prostate cancer - evaluate the effectiveness and side effects of the study drug
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Zoladex

Condition Name

Condition Name for Zoladex
Intervention Trials
Prostate Cancer 55
Breast Cancer 28
Prostate Adenocarcinoma 11
Stage III Prostate Cancer 8
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Condition MeSH

Condition MeSH for Zoladex
Intervention Trials
Prostatic Neoplasms 84
Breast Neoplasms 47
Adenocarcinoma 21
Carcinoma 5
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Clinical Trial Locations for Zoladex

Trials by Country

Trials by Country for Zoladex
Location Trials
United States 621
Canada 39
China 24
United Kingdom 15
Japan 12
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Trials by US State

Trials by US State for Zoladex
Location Trials
California 31
Texas 28
Massachusetts 23
Maryland 21
Illinois 19
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Clinical Trial Progress for Zoladex

Clinical Trial Phase

Clinical Trial Phase for Zoladex
Clinical Trial Phase Trials
Phase 4 11
Phase 3 42
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for Zoladex
Clinical Trial Phase Trials
Completed 63
Recruiting 21
Active, not recruiting 20
[disabled in preview] 47
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Clinical Trial Sponsors for Zoladex

Sponsor Name

Sponsor Name for Zoladex
Sponsor Trials
National Cancer Institute (NCI) 35
AstraZeneca 17
M.D. Anderson Cancer Center 9
[disabled in preview] 23
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Sponsor Type

Sponsor Type for Zoladex
Sponsor Trials
Other 167
Industry 75
NIH 39
[disabled in preview] 5
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