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Last Updated: December 3, 2022

CLINICAL TRIALS PROFILE FOR ZILEUTON


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All Clinical Trials for Zileuton

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00056004 ↗ Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia Completed National Cancer Institute (NCI) Phase 2 2003-06-01 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of zileuton may be an effective way to prevent lung cancer in patients who have bronchial dysplasia. PURPOSE: Randomized phase II trial to study the effectiveness of zileuton in preventing lung cancer in patients who have bronchial dysplasia.
NCT00056004 ↗ Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia Completed Barbara Ann Karmanos Cancer Institute Phase 2 2003-06-01 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of zileuton may be an effective way to prevent lung cancer in patients who have bronchial dysplasia. PURPOSE: Randomized phase II trial to study the effectiveness of zileuton in preventing lung cancer in patients who have bronchial dysplasia.
NCT00070486 ↗ Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 2003-12-01 RATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Celecoxib and zileuton may stop the growth of tumor cells by stopping blood flow to the tumor and may block the enzymes necessary for tumor cell growth. Combining chemotherapy with celecoxib and/or zileuton may kill more tumor cells. PURPOSE: Randomized phase II trial to study the effectiveness of combining celecoxib and/or zileuton with carboplatin and gemcitabine in treating patients who have advanced non-small cell lung cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Zileuton

Condition Name

Condition Name for Zileuton
Intervention Trials
Asthma 6
Chronic Myelogenous Leukemia 2
Tobacco Use Disorder 2
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Condition MeSH

Condition MeSH for Zileuton
Intervention Trials
Asthma 6
Leukemia, Myeloid 2
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2
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Clinical Trial Locations for Zileuton

Trials by Country

Trials by Country for Zileuton
Location Trials
United States 75
Brazil 1
India 1
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Trials by US State

Trials by US State for Zileuton
Location Trials
Massachusetts 9
California 6
Michigan 5
Minnesota 4
Maryland 4
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Clinical Trial Progress for Zileuton

Clinical Trial Phase

Clinical Trial Phase for Zileuton
Clinical Trial Phase Trials
Phase 4 5
Phase 3 2
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for Zileuton
Clinical Trial Phase Trials
Completed 14
Terminated 5
Recruiting 1
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Clinical Trial Sponsors for Zileuton

Sponsor Name

Sponsor Name for Zileuton
Sponsor Trials
National Cancer Institute (NCI) 4
Critical Therapeutics 4
University of Massachusetts, Worcester 2
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Sponsor Type

Sponsor Type for Zileuton
Sponsor Trials
Other 15
Industry 8
NIH 7
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