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Last Updated: January 17, 2022

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CLINICAL TRIALS PROFILE FOR ZESTRIL

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All Clinical Trials for Zestril

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00347360 ↗ The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) Trial Completed GlaxoSmithKline Phase 3 2006-07-01 This is a randomized, double-blind, double-dummy, parallel group trial employing 15 cells of a 4x4 factorial design (no placebo)to compare the hypertensive effects in patients with Stage 1 and Stage 2 hypertension of carvedilol (20, 40 or 80 mg daily) alone, lisinopril (10, 20 or 40 mg daily) alone, and all combinations of the doses.
NCT00552708 ↗ A Study Investigating the Bioequivalence of the Fixed Dose Combination of COREG CR to COREG CR and ZESTRIL. Completed GlaxoSmithKline Phase 1 2007-09-01 This study will be a randomized study investigating the bioequivalence of COREG CR to its components, COREG and Lisinopril (ZESTRIL). PK samples will be obtained throughout the study to investigate the PK of COREG CR FDC to COREG and Lisinopril
NCT00556920 ↗ Study to Demonstrate the Bioequivalence of the Fixed Dose Combination of COREG CRâ„¢ and Lisinopril to Its Components Completed GlaxoSmithKline Phase 1 2007-10-01 This study will be a randomized study investigating the bioequivalence of COREG CR and Lisinopril to COREG CR and ZESTRIL
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Zestril

Condition Name

Condition Name for Zestril
Intervention Trials
Hypertension 10
Healthy 4
Osteonecrosis 1
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Condition MeSH

Condition MeSH for Zestril
Intervention Trials
Hypertension 9
Malnutrition 2
Lung Neoplasms 1
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Clinical Trial Locations for Zestril

Trials by Country

Trials by Country for Zestril
Location Trials
United States 54
India 2
Sweden 1
France 1
Indonesia 1
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Trials by US State

Trials by US State for Zestril
Location Trials
California 4
Minnesota 4
North Carolina 3
New York 3
Nebraska 3
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Clinical Trial Progress for Zestril

Clinical Trial Phase

Clinical Trial Phase for Zestril
Clinical Trial Phase Trials
Phase 4 2
Phase 3 1
Phase 2 6
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Clinical Trial Status

Clinical Trial Status for Zestril
Clinical Trial Phase Trials
Completed 16
Recruiting 3
Unknown status 2
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Clinical Trial Sponsors for Zestril

Sponsor Name

Sponsor Name for Zestril
Sponsor Trials
National Cancer Institute (NCI) 3
GlaxoSmithKline 3
PharmaKinetics Laboratories Inc. 2
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Sponsor Type

Sponsor Type for Zestril
Sponsor Trials
Industry 17
Other 11
NIH 5
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