Transplanting Hepatitis C Kidneys Into Negative Kidney Recipients
Active, not recruiting
Merck Sharp & Dohme Corp.
Phase 1/Phase 2
2016-05-01
This study is being conducted to determine safety and effectiveness of transplanting kidneys
from Hepatitis C-positive donors into Hepatitis C-negative patients on the kidney transplant
waitlist, who will then be treated with the appropriate direct-acting antiviral (DAA) after
the single kidney transplantation.
Transplanting Hepatitis C Kidneys Into Negative Kidney Recipients
Active, not recruiting
University of Pennsylvania
Phase 1/Phase 2
2016-05-01
This study is being conducted to determine safety and effectiveness of transplanting kidneys
from Hepatitis C-positive donors into Hepatitis C-negative patients on the kidney transplant
waitlist, who will then be treated with the appropriate direct-acting antiviral (DAA) after
the single kidney transplantation.
Exploring Renal Transplants Using Hepatitis C Infected Donors for HCV-negative Recipients
Completed
Merck Sharp & Dohme Corp.
Phase 4
2016-07-20
In this study, individuals without hepatitis C infection who are on the kidney transplant
waitlist will receive a kidney from a deceased donor with hepatitis C infection and will be
treated for hepatitis C at the same time. Treatment will include Grazoprevir (GZR) 100
mg/Elbasvir (EBR) 50 mg administered on-call to the operating room for the renal transplant
procedure and continued for 12 weeks post-renal transplant.
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