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Last Updated: October 18, 2019

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CLINICAL TRIALS PROFILE FOR WELLCOVORIN

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Clinical Trials for Wellcovorin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00082706 Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant Active, not recruiting National Cancer Institute (NCI) Phase 2 2003-04-01 RATIONALE: Drugs used in chemotherapy, such as fluorouracil, leucovorin, gemcitabine, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving fluorouracil together with leucovorin, gemcitabine, and cisplatin works in treating patients with metastatic or unresectable adenocarcinoma of the urothelium or urachal remnant (part of the bladder).
NCT00082706 Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant Active, not recruiting M.D. Anderson Cancer Center Phase 2 2003-04-01 RATIONALE: Drugs used in chemotherapy, such as fluorouracil, leucovorin, gemcitabine, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving fluorouracil together with leucovorin, gemcitabine, and cisplatin works in treating patients with metastatic or unresectable adenocarcinoma of the urothelium or urachal remnant (part of the bladder).
NCT00508872 Folfox-B Study for Patients With Colorectal Liver Metastases Terminated Sanofi Phase 2 2005-11-01 Objective: - To evaluate the efficacy of the use of the combination of oxaliplatin, 5-fluorouracil, leucovorin and bevacizumab (FOLFOX-B) in patients with unresectable colorectal liver metastases, with the objective to downstage hepatic disease and enable complete resection of residual disease. Primary Objective: - To evaluate the resection rate in patients with initially unresectable hepatic colorectal metastases downstaged with FOLFOX-B. Complete resection of all liver lesions is the goal. Secondary Objectives: - To evaluate the probability of complete response, partial response or stable disease. - To evaluate the proportion of patients who are resected, and the proportion of patients achieving an R0 resection (among those receiving surgery). - To correlate survival with downstaging and resection based on metastatic colorectal prognostic score. - To evaluate the disease-free survival and overall survival. - To evaluate the positron emission tomography response rate. - To explore correlations of clinical response with telomerase and hTERT expression.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Wellcovorin

Condition Name

Condition Name for Wellcovorin
Intervention Trials
Leukemia 4
Colorectal Cancer 2
Stage IV Colorectal Cancer AJCC v7 2
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Condition MeSH

Condition MeSH for Wellcovorin
Intervention Trials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 8
Leukemia, Lymphoid 8
Leukemia 8
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Clinical Trial Locations for Wellcovorin

Trials by Country

Trials by Country for Wellcovorin
Location Trials
United States 37
Australia 4
Italy 4
New Zealand 1
United Kingdom 1
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Trials by US State

Trials by US State for Wellcovorin
Location Trials
Texas 12
Missouri 4
Florida 2
California 2
North Carolina 2
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Clinical Trial Progress for Wellcovorin

Clinical Trial Phase

Clinical Trial Phase for Wellcovorin
Clinical Trial Phase Trials
Phase 3 4
Phase 2 12
Phase 1/Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Wellcovorin
Clinical Trial Phase Trials
Not yet recruiting 8
Recruiting 8
Completed 4
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Clinical Trial Sponsors for Wellcovorin

Sponsor Name

Sponsor Name for Wellcovorin
Sponsor Trials
M.D. Anderson Cancer Center 13
National Cancer Institute (NCI) 8
Washington University School of Medicine 4
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Sponsor Type

Sponsor Type for Wellcovorin
Sponsor Trials
Other 28
Industry 14
NIH 8
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