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Last Updated: July 1, 2022

CLINICAL TRIALS PROFILE FOR VOCLOSPORIN


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All Clinical Trials for Voclosporin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00244842 ↗ Randomized Placebo-Controlled Study of ISA247 in Plaque Psoriasis Completed Aurinia Pharmaceuticals Inc. Phase 3 2004-12-01 The purpose of this study is to determine which dose of voclosporin is effective in the treatment of plaque psoriasis compared to placebo.
NCT00258713 ↗ A 36-Week Extension to Protocol ISA04-03 Completed Aurinia Pharmaceuticals Inc. Phase 3 2005-09-01 The purpose of this study is to determine the safety and efficacy of voclosporin in patients with plaque psoriasis.
NCT00270634 ↗ Study of ISA247 (Voclosporin) in De Novo Renal Transplantation Completed Aurinia Pharmaceuticals Inc. Phase 2 2006-01-01 This study will see if voclosporin is safe and effective in preventing kidney transplant rejection.
NCT00408187 ↗ Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients Completed Aurinia Pharmaceuticals Inc. Phase 3 2006-12-01 The purpose of this study is to determine the safety and efficacy of voclosporin in patients with plaque psoriasis.
NCT01236287 ↗ Special Access for the Use of Voclosporin for Kidney Transplantation Available Weill Medical College of Cornell University 1969-12-31 Voclosporin is an investigational medication previously studied to prevent acute rejection in patients who receive a kidney transplant. This study is a compassionate release program where subjects previously participating in the study entitled A Phase 2B, Randomized, Multicenter, Open-Label, Concentration Controlled, Safety Study of ISA247 and Tacrolimus (Prograf┬«) in denovo Renal Transplant Patients (ISA05-01)" may be eligible to continue to receive voclosporin despite the Phase 2B study being terminated by the sponsor. Under the compassionate release program, subjects previously taking voclosporin may continue to receive the study medication until the drug is FDA-approved and commercially available in the United States.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Voclosporin

Condition Name

Condition Name for Voclosporin
Intervention Trials
Lupus Nephritis 4
Psoriasis 3
Covid19 1
Drug-drug Interaction 1
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Condition MeSH

Condition MeSH for Voclosporin
Intervention Trials
Nephritis 5
Lupus Nephritis 5
Psoriasis 3
Keratoconjunctivitis Sicca 2
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Clinical Trial Locations for Voclosporin

Trials by Country

Trials by Country for Voclosporin
Location Trials
United States 109
Canada 30
Poland 3
Philippines 3
Brazil 2
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Trials by US State

Trials by US State for Voclosporin
Location Trials
California 7
North Carolina 7
Texas 6
Pennsylvania 6
New York 6
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Clinical Trial Progress for Voclosporin

Clinical Trial Phase

Clinical Trial Phase for Voclosporin
Clinical Trial Phase Trials
Phase 3 8
Phase 2/Phase 3 1
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for Voclosporin
Clinical Trial Phase Trials
Completed 12
Not yet recruiting 2
Active, not recruiting 1
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Clinical Trial Sponsors for Voclosporin

Sponsor Name

Sponsor Name for Voclosporin
Sponsor Trials
Aurinia Pharmaceuticals Inc. 16
Weill Medical College of Cornell University 1
Lux Biosciences, Inc. 1
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Sponsor Type

Sponsor Type for Voclosporin
Sponsor Trials
Industry 17
Other 3
NIH 1
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