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Last Updated: February 29, 2024

CLINICAL TRIALS PROFILE FOR VINCASAR PFS


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505(b)(2) Clinical Trials for Vincasar Pfs

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
OTC NCT03742258 ↗ Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma Active, not recruiting National Cancer Institute (NCI) Phase 1 2019-03-13 The purpose of this research study is to evaluate a new investigational drug, TAK-659, given in combination with standard chemotherapy, for the treatment of Diffuse Large B-cell Lymphoma (DLBCL). ?Investigational? means that TAK-659 has not been approved by the United States Food and Drug Administration (FDA) for use as a prescription or over-the-counter medication to treat a certain condition. The primary purpose of this study is to find the appropriate and safe dose of the study drug to be used in combination with standard chemotherapy for the treatment of your disease and to determine how well the drug works in treating the disease. Other objectives include measuring the amount of the study drug in the body at different times after taking the study drug. Participation in the study is expected to last for up to 3 years after receiving the last dose of the study drug. Patients will receive the study treatment for up to 18 weeks, as long as they are benefitting.
OTC NCT03742258 ↗ Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma Active, not recruiting Northwestern University Phase 1 2019-03-13 The purpose of this research study is to evaluate a new investigational drug, TAK-659, given in combination with standard chemotherapy, for the treatment of Diffuse Large B-cell Lymphoma (DLBCL). ?Investigational? means that TAK-659 has not been approved by the United States Food and Drug Administration (FDA) for use as a prescription or over-the-counter medication to treat a certain condition. The primary purpose of this study is to find the appropriate and safe dose of the study drug to be used in combination with standard chemotherapy for the treatment of your disease and to determine how well the drug works in treating the disease. Other objectives include measuring the amount of the study drug in the body at different times after taking the study drug. Participation in the study is expected to last for up to 3 years after receiving the last dose of the study drug. Patients will receive the study treatment for up to 18 weeks, as long as they are benefitting.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Vincasar Pfs

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004010 ↗ Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease Completed National Cancer Institute (NCI) Phase 2 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving radiation therapy after chemotherapy may be an effective treatment for Hodgkin's disease. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and radiation therapy in treating children who have previously untreated stage II, stage III, or stage IV Hodgkin's disease.
NCT00004010 ↗ Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease Completed Children's Oncology Group Phase 2 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving radiation therapy after chemotherapy may be an effective treatment for Hodgkin's disease. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and radiation therapy in treating children who have previously untreated stage II, stage III, or stage IV Hodgkin's disease.
NCT00026208 ↗ Combination Chemotherapy Plus Low-Dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma Completed Stanford University Phase 2 2001-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: This phase 2 trial is studying how well giving combination chemotherapy together with low-dose radiation therapy works in treating patients with stage I or stage IIA Hodgkin's lymphoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Vincasar Pfs

Condition Name

Condition Name for Vincasar Pfs
Intervention Trials
Acute Lymphoblastic Leukemia 20
Untreated Adult Acute Lymphoblastic Leukemia 13
B Acute Lymphoblastic Leukemia 11
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Condition MeSH

Condition MeSH for Vincasar Pfs
Intervention Trials
Lymphoma 43
Leukemia 42
Precursor Cell Lymphoblastic Leukemia-Lymphoma 40
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Clinical Trial Locations for Vincasar Pfs

Trials by Country

Trials by Country for Vincasar Pfs
Location Trials
Canada 231
Australia 95
New Zealand 35
Puerto Rico 25
Switzerland 8
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Trials by US State

Trials by US State for Vincasar Pfs
Location Trials
Texas 62
Ohio 58
California 58
New York 56
Illinois 56
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Clinical Trial Progress for Vincasar Pfs

Clinical Trial Phase

Clinical Trial Phase for Vincasar Pfs
Clinical Trial Phase Trials
Phase 3 31
Phase 2/Phase 3 4
Phase 2 34
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Clinical Trial Status

Clinical Trial Status for Vincasar Pfs
Clinical Trial Phase Trials
Active, not recruiting 36
Recruiting 29
Completed 15
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Clinical Trial Sponsors for Vincasar Pfs

Sponsor Name

Sponsor Name for Vincasar Pfs
Sponsor Trials
National Cancer Institute (NCI) 85
Children's Oncology Group 25
M.D. Anderson Cancer Center 13
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Sponsor Type

Sponsor Type for Vincasar Pfs
Sponsor Trials
NIH 85
Other 75
Industry 22
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