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CLINICAL TRIALS PROFILE FOR VEPESID

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Clinical Trials for Vepesid

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00002835	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	National Cancer Institute (NCI)	Phase 3	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
NCT00002835	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	M.D. Anderson Cancer Center	Phase 3	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
NCT00006047	Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide	Completed	Astex Pharmaceuticals	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of nitrocamptothecin plus etoposide in treating patients who have advanced solid tumors.
NCT00006047	Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide	Completed	National Cancer Institute (NCI)	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of nitrocamptothecin plus etoposide in treating patients who have advanced solid tumors.
NCT00006047	Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide	Completed	H. Lee Moffitt Cancer Center and Research Institute	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of nitrocamptothecin plus etoposide in treating patients who have advanced solid tumors.
NCT00006373	Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma	Completed	National Cancer Institute (NCI)	Phase 2	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by autologous bone marrow transplantation or peripheral stem cell transplantation in treating patients who have non-Hodgkin's lymphoma or Hodgkin's lymphoma.
NCT00006373	Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma	Completed	H. Lee Moffitt Cancer Center and Research Institute	Phase 2	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by autologous bone marrow transplantation or peripheral stem cell transplantation in treating patients who have non-Hodgkin's lymphoma or Hodgkin's lymphoma.

Clinical Trial Conditions for Vepesid

Condition Name

Condition Name for Vepesid
Intervention	Trials
Lymphoma	4
Refractory Diffuse Large B-Cell Lymphoma	3
Recurrent Diffuse Large B-Cell Lymphoma	3
Recurrent Hodgkin Lymphoma	2

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Condition MeSH

Condition MeSH for Vepesid
Intervention	Trials
Lymphoma	19
Lymphoma, Non-Hodgkin	8
Lymphoma, B-Cell	8
Hodgkin Disease	6

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Clinical Trial Locations for Vepesid

Trials by Country

Trials by Country for Vepesid
Location	Trials
United States	82
Italy	3
South Africa	2
Israel	1
Brazil	1

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Trials by US State

Trials by US State for Vepesid
Location	Trials
Texas	13
California	8
New York	5
Florida	5
Pennsylvania	4

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Clinical Trial Progress for Vepesid

Clinical Trial Phase

Clinical Trial Phase for Vepesid
Clinical Trial Phase	Trials
Phase 3	6
Phase 2/Phase 3	1
Phase 2	16

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Clinical Trial Status

Clinical Trial Status for Vepesid
Clinical Trial Phase	Trials
Recruiting	11
Not yet recruiting	10
Active, not recruiting	5

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Clinical Trial Sponsors for Vepesid

Sponsor Name

Sponsor Name for Vepesid
Sponsor	Trials
National Cancer Institute (NCI)	18
M.D. Anderson Cancer Center	10
City of Hope Medical Center	3

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Sponsor Type

Sponsor Type for Vepesid
Sponsor	Trials
Other	39
NIH	19
Industry	9

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