Randomized, Double-Blind, Placebo-Controlled, Forced-Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Weeks in Patients With Stage 1 and Stage 2 Hypertension
The primary objective of this study is to compare the effectiveness of telmisartan 80 mg /
hydrochlorothiazide 25 mg [Micardis HCT] to valsartan 160 mg / hydrochlorothiazide 25 mg
[Diovan HCT] and placebo in the treatment of Stage 1 and Stage 2 hypertension.
A 16 Week Study to Evaluate the Effect on Insulin Sensitivity of Valsartan (320 mg) and Hydrochlorothiazide (25 mg) Combined and Alone, in Patients With Metabolic Syndrome
The metabolic syndrome is a classification for patients with a constellation of risk factors
which may include abdominal obesity, hypertension, elevated blood lipids and sugar. Three or
more of these factors together constitute the metabolic syndrome and place these patients at
a greater risk for the development of diabetes and cardiovascular diseases. The purpose of
this study is to determine whether two common drugs to lower blood pressure, whether used
separately or in combination, have different effects on blood sugar levels in patients
diagnosed with the metabolic syndrome.
VALORY Study of Valsartan/Hydrochlorizide for Patients Who do Not Respond Adequately to Olmesartan Medoxomil
To evaluate the efficacy of valsartan 160 mg/HCTZ 25 mg in patients not adequately responding
to monotherapy with olmesartan medoxomil 40 mg or combination therapy with olmesartan
medoxomil 20 mg plus HCTZ 12.5 mg by testing the hypothesis that valsartan 160 mg/HCTZ 25 mg
significantly reduces the trough mean sitting diastolic blood pressure (MSDBP) after a 4-week
treatment in the nonresponder population.
Efficacy and Safety of Valsartan Versus Amlodipine in Postmenopausal Women With Hypertension
The purpose of this study is compare treatment with valsartan with the possible addition of a
diuretic, hydrochlorothiazide, on high blood pressure with the drug amlodipine with the
possible addition of a diuretic, hydrochlorothiazide. In particular, the effect of treatment
on the stiffness of the blood vessels will be studied.
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