Treatment Trial Evaluating Long Acting Insulin in Type 1 Diabetes
Patients with type 1 diabetes trained in multiple daily insulin injection were treated with
two diffferent kinds of long acting insulin preparations. The two insulin preparations were
glargine and ultralente insulin. Patients were randomized to receive one of the two insulin
preparations for the first 4 months followed by the second preparation for a further four
months. Short acting insulin used was the same during both periods. We found that glargine
insulin was better than ultralente insulin in our study.
Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 2 Diabetes
To determine, in subjects with Type 2 Diabetes Mellitus:
1. Whether glycemic control can be achieved at least as effectively with an insulin
regimen involving pre-meal EXUBERA™ (inhaled insulin) plus a single bedtime Ultralente
injection as with a conventional subcutaneous insulin regimen involving 2 mixed
Regular/NPH insulin injections per day.
2. The toleration and safety of EXUBERA™ (inhaled insulin) therapy and its effects after 6
months, if any, on measures of pulmonary function.
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