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Last Updated: April 26, 2024

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CLINICAL TRIALS PROFILE FOR TUKYSA


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All Clinical Trials for Tukysa

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03043313 ↗ Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Active, not recruiting Academic and Community Cancer Research United Phase 2 2017-06-23 This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, participants enrolled into Cohort A and received both tucatinib and trastuzumab. In the second part of this study, participants are randomly assigned to either Cohort B or Cohort C. Participants in Cohort B will receive tucatinib and trastuzumab. Participants in Cohort C will receive tucatinib. Participants in Cohort C who do not respond to therapy may have an option to receive tucatinib plus trastuzumab.
NCT03043313 ↗ Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Active, not recruiting Cascadian Therapeutics Inc. Phase 2 2017-06-23 This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, participants enrolled into Cohort A and received both tucatinib and trastuzumab. In the second part of this study, participants are randomly assigned to either Cohort B or Cohort C. Participants in Cohort B will receive tucatinib and trastuzumab. Participants in Cohort C will receive tucatinib. Participants in Cohort C who do not respond to therapy may have an option to receive tucatinib plus trastuzumab.
NCT03043313 ↗ Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Active, not recruiting National Cancer Institute (NCI) Phase 2 2017-06-23 This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, participants enrolled into Cohort A and received both tucatinib and trastuzumab. In the second part of this study, participants are randomly assigned to either Cohort B or Cohort C. Participants in Cohort B will receive tucatinib and trastuzumab. Participants in Cohort C will receive tucatinib. Participants in Cohort C who do not respond to therapy may have an option to receive tucatinib plus trastuzumab.
NCT03043313 ↗ Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Active, not recruiting Seagen Inc. Phase 2 2017-06-23 This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, participants enrolled into Cohort A and received both tucatinib and trastuzumab. In the second part of this study, participants are randomly assigned to either Cohort B or Cohort C. Participants in Cohort B will receive tucatinib and trastuzumab. Participants in Cohort C will receive tucatinib. Participants in Cohort C who do not respond to therapy may have an option to receive tucatinib plus trastuzumab.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Tukysa

Condition Name

Condition Name for Tukysa
Intervention Trials
Breast Cancer 5
HER2-positive Breast Cancer 3
Colorectal Carcinoma 2
HER2-positive Metastatic Breast Cancer 2
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Condition MeSH

Condition MeSH for Tukysa
Intervention Trials
Breast Neoplasms 9
Colorectal Neoplasms 4
Neoplasm Metastasis 3
Adenocarcinoma 3
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Clinical Trial Locations for Tukysa

Trials by Country

Trials by Country for Tukysa
Location Trials
United States 37
Spain 13
Japan 8
France 1
Australia 1
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Trials by US State

Trials by US State for Tukysa
Location Trials
California 4
North Carolina 3
Washington 2
Ohio 2
Illinois 2
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Clinical Trial Progress for Tukysa

Clinical Trial Phase

Clinical Trial Phase for Tukysa
Clinical Trial Phase Trials
Phase 2 8
Phase 1/Phase 2 5
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Clinical Trial Status

Clinical Trial Status for Tukysa
Clinical Trial Phase Trials
Not yet recruiting 9
Recruiting 3
Active, not recruiting 1
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Clinical Trial Sponsors for Tukysa

Sponsor Name

Sponsor Name for Tukysa
Sponsor Trials
Seagen Inc. 8
Academic and Community Cancer Research United 3
Seattle Genetics, Inc. 2
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Sponsor Type

Sponsor Type for Tukysa
Sponsor Trials
Industry 18
Other 9
NIH 2
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