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Last Updated: June 13, 2021

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CLINICAL TRIALS PROFILE FOR TUCATINIB

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All Clinical Trials for Tucatinib

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03043313 Tucatinib (ONT-380) and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer (MOUNTAINEER) Not yet recruiting Cascadian Therapeutics Inc. Phase 2 2017-06-23 This is a phase II trial that will study how well tucatinib (ONT-380) and trastuzumab work in treating patients with colorectal cancer with a specific genetic marker (human epidermal growth factor receptor 2 - HER2) that has spread to other places in the body or has come back and cannot be removed by surgery. Tucatinib has been found to specifically target and inhibit HER2.
NCT03043313 Tucatinib (ONT-380) and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer (MOUNTAINEER) Not yet recruiting National Cancer Institute (NCI) Phase 2 2017-06-23 This is a phase II trial that will study how well tucatinib (ONT-380) and trastuzumab work in treating patients with colorectal cancer with a specific genetic marker (human epidermal growth factor receptor 2 - HER2) that has spread to other places in the body or has come back and cannot be removed by surgery. Tucatinib has been found to specifically target and inhibit HER2.
NCT03043313 Tucatinib (ONT-380) and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer (MOUNTAINEER) Not yet recruiting Academic and Community Cancer Research United Phase 2 2017-06-23 This is a phase II trial that will study how well tucatinib (ONT-380) and trastuzumab work in treating patients with colorectal cancer with a specific genetic marker (human epidermal growth factor receptor 2 - HER2) that has spread to other places in the body or has come back and cannot be removed by surgery. Tucatinib has been found to specifically target and inhibit HER2.
NCT03501979 Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD Not yet recruiting Johns Hopkins University Phase 2 2018-10-01 A phase 2 non-randomized study to assess the safety and efficacy of the combination of tucatinib and trastuzumab with capecitabine for the treatment of leptomeningeal metastases in HER2-neu positive breast cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Tucatinib

Condition Name

Condition Name for Tucatinib
Intervention Trials
Breast Cancer 5
Healthy 3
HER2-positive Breast Cancer 3
Gastric Adenocarcinoma 2
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Condition MeSH

Condition MeSH for Tucatinib
Intervention Trials
Breast Neoplasms 11
Adenocarcinoma 3
Neoplasm Metastasis 2
Neoplasms 2
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Clinical Trial Locations for Tucatinib

Trials by Country

Trials by Country for Tucatinib
Location Trials
United States 18
Australia 1
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Trials by US State

Trials by US State for Tucatinib
Location Trials
California 4
Texas 4
Tennessee 2
Florida 2
Washington 1
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Clinical Trial Progress for Tucatinib

Clinical Trial Phase

Clinical Trial Phase for Tucatinib
Clinical Trial Phase Trials
Phase 3 2
Phase 2/Phase 3 1
Phase 2 8
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Clinical Trial Status

Clinical Trial Status for Tucatinib
Clinical Trial Phase Trials
Not yet recruiting 18
Recruiting 2
Completed 1
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Clinical Trial Sponsors for Tucatinib

Sponsor Name

Sponsor Name for Tucatinib
Sponsor Trials
Seattle Genetics, Inc. 13
National Cancer Institute (NCI) 2
Cascadian Therapeutics Inc. 2
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Sponsor Type

Sponsor Type for Tucatinib
Sponsor Trials
Industry 21
Other 9
NIH 2
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