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Last Updated: January 26, 2023

CLINICAL TRIALS PROFILE FOR TREXALL


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All Clinical Trials for Trexall

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004228 ↗ Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma Completed National Cancer Institute (NCI) Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for lymphoblastic lymphoma. PURPOSE: This randomized phase III trial is studying different regimens of combination chemotherapy to compare how well they work in treating children or adolescents with newly diagnosed stage III or stage IV lymphoblastic lymphoma.
NCT00004228 ↗ Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma Completed Children's Oncology Group Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for lymphoblastic lymphoma. PURPOSE: This randomized phase III trial is studying different regimens of combination chemotherapy to compare how well they work in treating children or adolescents with newly diagnosed stage III or stage IV lymphoblastic lymphoma.
NCT00022516 ↗ Low-dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-negative Early Breast Cancer Completed International Breast Cancer Study Group Phase 3 2000-11-01 This randomized, phase III trial was designed to test the efficacy of a low-dose chemotherapy-maintenance regimen, hypothesized to have anti-angiogenic activity, administered following standard chemotherapy in patients with early breast cancer whose tumors are hormone receptor negative.
NCT00075725 ↗ Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2003-12-29 This randomized phase III trial is studying dexamethasone to see how well it works compared to prednisone during induction therapy. This trial is also studying methotrexate and leucovorin calcium to see how well they work compared to methotrexate alone during maintenance therapy in treating patients with newly diagnosed acute lymphoblastic leukemia (ALL). Drugs used in chemotherapy, such as dexamethasone, prednisone, methotrexate, and leucovorin calcium, work in different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Trexall

Condition Name

Condition Name for Trexall
Intervention Trials
Acute Lymphoblastic Leukemia 9
Leukemia 5
Lymphoblastic Leukemia, Acute, Childhood 3
Hematopoietic Stem Cell Transplantation 3
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Condition MeSH

Condition MeSH for Trexall
Intervention Trials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 21
Leukemia 20
Leukemia, Lymphoid 18
Graft vs Host Disease 7
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Clinical Trial Locations for Trexall

Trials by Country

Trials by Country for Trexall
Location Trials
United States 446
Canada 62
Australia 29
Switzerland 4
Brazil 4
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Trials by US State

Trials by US State for Trexall
Location Trials
California 19
Illinois 18
Maryland 18
Ohio 17
Michigan 17
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Clinical Trial Progress for Trexall

Clinical Trial Phase

Clinical Trial Phase for Trexall
Clinical Trial Phase Trials
Phase 4 2
Phase 3 7
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Trexall
Clinical Trial Phase Trials
Completed 21
Terminated 8
Active, not recruiting 7
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Clinical Trial Sponsors for Trexall

Sponsor Name

Sponsor Name for Trexall
Sponsor Trials
National Cancer Institute (NCI) 13
Therapeutic Advances in Childhood Leukemia Consortium 7
Children's Oncology Group 5
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Sponsor Type

Sponsor Type for Trexall
Sponsor Trials
Other 72
Industry 23
NIH 15
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