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Last Updated: February 18, 2020

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CLINICAL TRIALS PROFILE FOR TRAVOPROST

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505(b)(2) Clinical Trials for Travoprost

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
New Formulation NCT00670033 Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension Completed Alcon Research Phase 2 2008-04-01 The purpose of this study was to describe the safety and IOP-lowering efficacy of Travoprost New Formulations compared to TRAVATAN® and to vehicle in patients with open-angle glaucoma or ocular hypertension.
New Formulation NCT01452009 Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004% Withdrawn Alcon Research Phase 3 2011-11-01 A multi-center, observer-masked, randomized, parallel group efficacy and safety study of TRAVATAN® versus a new formulation of Travoprost Ophthalmic Solution, 0.004%
New Formulation NCT01658839 Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients Completed Alcon Research Phase 1 2013-01-01 The purpose of this study was to assess the safety and describe the steady-state plasma pharmacokinetic (PK) profiles of Travoprost ophthalmic solution, 0.004% (new formulation) following a once daily administration for 7 days in pediatric glaucoma or ocular hypertension patients.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Travoprost

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00051142 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) Completed Alcon Research Phase 3 2001-02-01 The purpose of this study is to evaluate the safety and IOP-lowering efficacy of Travoprost (0.004%) compared to Latanoprost (0.005%) in patients with chronic open-angle glaucoma or ocular hypertension.
NCT00051181 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma Completed Alcon Research Phase 3 2000-01-01 To demonstrate that the intraocular pressure(IOP)-lowering efficacy of Travoprost (0.004%) is equal or better than that of Latanoprost 0.005% in patients with chronic angle-closure glaucoma.
NCT00121147 Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan Completed Alcon Research N/A 2003-09-01 The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
NCT00121147 Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan Completed Hermann Eye Center N/A 2003-09-01 The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Travoprost

Condition Name

Condition Name for Travoprost
Intervention Trials
Ocular Hypertension 58
Glaucoma 39
Open-angle Glaucoma 23
Open Angle Glaucoma 8
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Condition MeSH

Condition MeSH for Travoprost
Intervention Trials
Glaucoma 77
Ocular Hypertension 66
Glaucoma, Open-Angle 52
Hypertension 49
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Clinical Trial Locations for Travoprost

Trials by Country

Trials by Country for Travoprost
Location Trials
United States 90
Canada 6
Germany 3
Italy 3
Greece 3
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Trials by US State

Trials by US State for Travoprost
Location Trials
Texas 15
California 7
Ohio 5
Pennsylvania 4
New York 4
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Clinical Trial Progress for Travoprost

Clinical Trial Phase

Clinical Trial Phase for Travoprost
Clinical Trial Phase Trials
Phase 4 54
Phase 3 18
Phase 2 11
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Clinical Trial Status

Clinical Trial Status for Travoprost
Clinical Trial Phase Trials
Completed 71
Recruiting 7
Terminated 5
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Clinical Trial Sponsors for Travoprost

Sponsor Name

Sponsor Name for Travoprost
Sponsor Trials
Alcon Research 56
Allergan 6
Glaukos Corporation 6
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Sponsor Type

Sponsor Type for Travoprost
Sponsor Trials
Industry 81
Other 22
U.S. Fed 1
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