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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR TRAVOPROST

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Clinical Trials for Travoprost

Trial ID Title Status Sponsor Phase Summary
NCT00051142 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) Completed Alcon Research Phase 3 The purpose of this study is to evaluate the safety and IOP-lowering efficacy of Travoprost (0.004%) compared to Latanoprost (0.005%) in patients with chronic open-angle glaucoma or ocular hypertension.
NCT00051181 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma Completed Alcon Research Phase 3 To demonstrate that the intraocular pressure(IOP)-lowering efficacy of Travoprost (0.004%) is equal or better than that of Latanoprost 0.005% in patients with chronic angle-closure glaucoma.
NCT00121147 Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan Completed Alcon Research N/A The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
NCT00121147 Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan Completed Hermann Eye Center N/A The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
NCT00308945 Influence of Prostaglandins on Ocular Blood Flow in Glaucoma Patients Completed University Hospital, Basel, Switzerland Phase 4 Vasoactivity of topical drugs may be of prognostic relevance in glaucoma. There is very little information for a major class, the prostaglandin analogues with regard to this aspect. The purpose of this study is to compare the effect of travoprost 0.004% and latanoprost 0.005% on choroidal blood flow and retinal vascular diameter in glaucoma patients. After washout of current topical medication, intraocular pressure (IOP) in both eyes (Goldmann applanation tonometry), choroidal blood flow (laser Doppler flowmetry) and retinal vessel diameter (Retinal Vessel Analyzer) in one randomly selected eye will be measured at baseline, after two weeks and after 4 weeks of treatment with travoprost or latanoprost QD, in a randomized, double masked 2-way cross-over study in 20 open angle glaucoma patients.
NCT00331240 24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination Completed Aristotle University Of Thessaloniki Phase 3 The purpose of this study is to compare the short-term (8 week) mean 24-hour intraocular pressure control and safety of TravTim fixed combination given once in the evening with placebo once in the morning versus TravTim given once in the morning with placebo once in the evening in patients with open-angle glaucoma.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Travoprost

Condition Name

Condition Name for Travoprost
Intervention Trials
Ocular Hypertension 57
Glaucoma 38
Open-Angle Glaucoma 23
Open Angle Glaucoma 8
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Condition MeSH

Condition MeSH for Travoprost
Intervention Trials
Glaucoma 76
Ocular Hypertension 64
Glaucoma, Open-Angle 50
Hypertension 49
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Clinical Trial Locations for Travoprost

Trials by Country

Trials by Country for Travoprost
Location Trials
United States 88
Canada 6
Germany 3
Italy 3
Greece 3
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Trials by US State

Trials by US State for Travoprost
Location Trials
Texas 15
California 7
Illinois 4
Georgia 4
Ohio 4
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Clinical Trial Progress for Travoprost

Clinical Trial Phase

Clinical Trial Phase for Travoprost
Clinical Trial Phase Trials
Phase 4 54
Phase 3 16
Phase 2 11
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Clinical Trial Status

Clinical Trial Status for Travoprost
Clinical Trial Phase Trials
Completed 71
Recruiting 5
Terminated 5
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Clinical Trial Sponsors for Travoprost

Sponsor Name

Sponsor Name for Travoprost
Sponsor Trials
Alcon Research 56
Allergan 6
Glaukos Corporation 5
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Sponsor Type

Sponsor Type for Travoprost
Sponsor Trials
Industry 78
Other 22
U.S. Fed 1
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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
QuintilesIMS
Accenture
Mallinckrodt
Cerilliant
Queensland Health
AstraZeneca
Citi
Baxter

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