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Generated: December 15, 2018

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CLINICAL TRIALS PROFILE FOR TIROFIBAN HYDROCHLORIDE

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Clinical Trials for Tirofiban Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00126139 Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Terminated Eli Lilly and Company Phase 3 The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic strokes before and during carotid endarterectomy [CEA] (primary endpoints); and the degree of carotid stenosis, number of microembolic signal (MES) counts, number of ischemic infarcts at diffusion weighted imaging (DWI) and amount of intraluminal thrombus at pathological examination (secondary endpoints) in patients with ischemic stroke due to a >50% carotid stenosis who will undergo CEA.
NCT00126139 Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Terminated Schweizerische Herzstiftung Phase 3 The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic strokes before and during carotid endarterectomy [CEA] (primary endpoints); and the degree of carotid stenosis, number of microembolic signal (MES) counts, number of ischemic infarcts at diffusion weighted imaging (DWI) and amount of intraluminal thrombus at pathological examination (secondary endpoints) in patients with ischemic stroke due to a >50% carotid stenosis who will undergo CEA.
NCT00126139 Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Terminated University of Zurich Phase 3 The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic strokes before and during carotid endarterectomy [CEA] (primary endpoints); and the degree of carotid stenosis, number of microembolic signal (MES) counts, number of ischemic infarcts at diffusion weighted imaging (DWI) and amount of intraluminal thrombus at pathological examination (secondary endpoints) in patients with ischemic stroke due to a >50% carotid stenosis who will undergo CEA.
NCT00251576 Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180) Completed Merck Sharp & Dohme Corp. Phase 3 A-Phase: Evaluating patients with chest pain who are receiving approved drugs, to estimate the effectiveness of one type of blood thinner as compared to another type of blood thinner. Z-Phase: To evaluate early treatment of patients with long term chest pain (using an approved drug for 30 days, followed by an increased dose of the drug) as compared to patients (treated with diet and 4 months placebo followed by diet and approved drug) in patients who have experienced acute chest pain or heart attack.
NCT00300833 Treating Acute MI Patients With Aggrastat on Their Way to Hospital Unknown status The Baruch Padeh Medical Center, Poriya Phase 4 Treating an AMI patient with ST elevation with Aggrastat in the ambulance on his or her way to the hospital.
NCT00373451 Randomized Comparison of Abciximab Plus Heparin With Bivalirudin in Acute Coronary Syndrome Completed Deutsches Herzzentrum Muenchen Phase 4 The purpose of this study is to determine which of these anti-clotting medications, abciximab plus unfractionated heparin or bivalirudin, is more effective to prevent thrombotic and bleeding complications in patients suffering from a heart attack and undergoing coronary intervention.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Tirofiban Hydrochloride

Condition Name

Condition Name for Tirofiban Hydrochloride
Intervention Trials
Myocardial Infarction 7
Coronary Artery Disease 7
Acute Myocardial Infarction 6
ST Segment Elevation Myocardial Infarction 3
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Condition MeSH

Condition MeSH for Tirofiban Hydrochloride
Intervention Trials
Myocardial Infarction 20
Infarction 20
Coronary Artery Disease 10
Coronary Disease 9
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Clinical Trial Locations for Tirofiban Hydrochloride

Trials by Country

Trials by Country for Tirofiban Hydrochloride
Location Trials
Italy 11
United States 10
China 9
France 3
Korea, Republic of 3
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Trials by US State

Trials by US State for Tirofiban Hydrochloride
Location Trials
New York 3
Florida 2
Oklahoma 1
Georgia 1
Virginia 1
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Clinical Trial Progress for Tirofiban Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Tirofiban Hydrochloride
Clinical Trial Phase Trials
Phase 4 24
Phase 3 9
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Tirofiban Hydrochloride
Clinical Trial Phase Trials
Completed 21
Recruiting 6
Unknown status 6
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Clinical Trial Sponsors for Tirofiban Hydrochloride

Sponsor Name

Sponsor Name for Tirofiban Hydrochloride
Sponsor Trials
Medicure 3
Merck Sharp & Dohme Corp. 3
Zhoukou Central Hospital 2
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Sponsor Type

Sponsor Type for Tirofiban Hydrochloride
Sponsor Trials
Other 101
Industry 10
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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
QuintilesIMS
Cantor Fitzgerald
Deloitte
Express Scripts
McKinsey
Merck
Dow
Chubb

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