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Last Updated: May 28, 2022

CLINICAL TRIALS PROFILE FOR TIBSOVO


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All Clinical Trials for Tibsovo

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03471260 ↗ Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies Recruiting AbbVie Phase 1/Phase 2 2018-03-19 This phase Ib/II trial studies the side effects and best dose of venetoclax and how well it works when given together with ivosidenib with or without azacitidine, in treating patients with IDH1-mutated hematologic malignancies. Venetoclax and ivosidenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ivosidenib and venetoclax with azacitidine may work better in treating patients with hematologic malignancies compared to ivosidenib and venetoclax alone.
NCT03471260 ↗ Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies Recruiting Agios Pharmaceuticals, Inc. Phase 1/Phase 2 2018-03-19 This phase Ib/II trial studies the side effects and best dose of venetoclax and how well it works when given together with ivosidenib with or without azacitidine, in treating patients with IDH1-mutated hematologic malignancies. Venetoclax and ivosidenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ivosidenib and venetoclax with azacitidine may work better in treating patients with hematologic malignancies compared to ivosidenib and venetoclax alone.
NCT03471260 ↗ Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies Recruiting M.D. Anderson Cancer Center Phase 1/Phase 2 2018-03-19 This phase Ib/II trial studies the side effects and best dose of venetoclax and how well it works when given together with ivosidenib with or without azacitidine, in treating patients with IDH1-mutated hematologic malignancies. Venetoclax and ivosidenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ivosidenib and venetoclax with azacitidine may work better in treating patients with hematologic malignancies compared to ivosidenib and venetoclax alone.
NCT04088188 ↗ Gemcitabine and Cisplatin With Ivosidenib or Pemigatinib for the Treatment of Unresectable or Metastatic Cholangiocarcinoma Recruiting National Cancer Institute (NCI) Phase 1 2021-01-25 This phase I trial studies the side effects and best dose of gemcitabine and cisplatin when given together with ivosidenib or pemigatinib in treating patients with cholangiocarcinoma that cannot be removed with surgery (unresectable) or has spread to other places in the body (metastatic). Chemotherapy drugs, such as gemcitabine and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Ivosidenib and pemigatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gemcitabine and cisplatin with ivosidenib or pemigatinib may work better in treating patients with cholangiocarcinoma compared to gemcitabine and cisplatin alone.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Tibsovo

Condition Name

Condition Name for Tibsovo
Intervention Trials
Recurrent Acute Myeloid Leukemia 5
Refractory Acute Myeloid Leukemia 4
Acute Myeloid Leukemia 4
Myeloproliferative Neoplasm 3
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Condition MeSH

Condition MeSH for Tibsovo
Intervention Trials
Leukemia, Myeloid, Acute 7
Leukemia, Myeloid 7
Leukemia 7
Myeloproliferative Disorders 4
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Clinical Trial Locations for Tibsovo

Trials by Country

Trials by Country for Tibsovo
Location Trials
United States 70
China 1
Puerto Rico 1
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Trials by US State

Trials by US State for Tibsovo
Location Trials
Texas 6
Illinois 3
Minnesota 3
New York 3
Ohio 3
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Clinical Trial Progress for Tibsovo

Clinical Trial Phase

Clinical Trial Phase for Tibsovo
Clinical Trial Phase Trials
Phase 2 3
Phase 1/Phase 2 2
Phase 1 6
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Clinical Trial Status

Clinical Trial Status for Tibsovo
Clinical Trial Phase Trials
Not yet recruiting 5
Recruiting 5
Active, not recruiting 1
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Clinical Trial Sponsors for Tibsovo

Sponsor Name

Sponsor Name for Tibsovo
Sponsor Trials
National Cancer Institute (NCI) 6
M.D. Anderson Cancer Center 4
Agios Pharmaceuticals, Inc. 2
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Sponsor Type

Sponsor Type for Tibsovo
Sponsor Trials
Other 11
NIH 6
Industry 4
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