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Generated: December 13, 2018

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CLINICAL TRIALS PROFILE FOR THYROTROPIN ALFA

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Clinical Trials for Thyrotropin Alfa

Trial ID Title Status Sponsor Phase Summary
NCT00004778 Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women With Threatened Premature Delivery Completed Children's Hospital of Philadelphia Phase 3 OBJECTIVES: I. Evaluate the effect of thyrotropin-releasing hormone (TRH) on the severity of initial lung disease and occurrence of chronic lung disease when given antenatally to women with threatened premature delivery. II. Evaluate possible mechanisms for the effects of TRH on the severity and incidence of chronic lung disease. III. Investigate whether a deficiency in endogenous cortisol and/or thyroid hormones after birth influences the severity of lung disease and the development of chronic lung disease.
NCT00004778 Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women With Threatened Premature Delivery Completed Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Phase 3 OBJECTIVES: I. Evaluate the effect of thyrotropin-releasing hormone (TRH) on the severity of initial lung disease and occurrence of chronic lung disease when given antenatally to women with threatened premature delivery. II. Evaluate possible mechanisms for the effects of TRH on the severity and incidence of chronic lung disease. III. Investigate whether a deficiency in endogenous cortisol and/or thyroid hormones after birth influences the severity of lung disease and the development of chronic lung disease.
NCT00004778 Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women With Threatened Premature Delivery Completed National Center for Research Resources (NCRR) Phase 3 OBJECTIVES: I. Evaluate the effect of thyrotropin-releasing hormone (TRH) on the severity of initial lung disease and occurrence of chronic lung disease when given antenatally to women with threatened premature delivery. II. Evaluate possible mechanisms for the effects of TRH on the severity and incidence of chronic lung disease. III. Investigate whether a deficiency in endogenous cortisol and/or thyroid hormones after birth influences the severity of lung disease and the development of chronic lung disease.
NCT00004840 Study of Antenatal Thyrotropin-Releasing Hormone in Women in Premature Labor to Prevent Lung Disease in Preterm Infants Completed Children's Hospital of Philadelphia N/A OBJECTIVES: I. Assess the efficacy and safety of antenatal administration of thyrotropin-releasing hormone to women in premature labor to improve pulmonary outcomes in preterm infants.
NCT00004840 Study of Antenatal Thyrotropin-Releasing Hormone in Women in Premature Labor to Prevent Lung Disease in Preterm Infants Completed Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) N/A OBJECTIVES: I. Assess the efficacy and safety of antenatal administration of thyrotropin-releasing hormone to women in premature labor to improve pulmonary outcomes in preterm infants.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Thyrotropin Alfa

Condition Name

Condition Name for Thyrotropin Alfa
Intervention Trials
Subclinical Hypothyroidism 2
Graves' Disease 2
Respiratory Distress Syndrome 2
Thyroid Disease 2
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Condition MeSH

Condition MeSH for Thyrotropin Alfa
Intervention Trials
Thyroid Diseases 7
Thyroid Neoplasms 4
Goiter 3
Hypothyroidism 3
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Clinical Trial Locations for Thyrotropin Alfa

Trials by Country

Trials by Country for Thyrotropin Alfa
Location Trials
United States 13
Denmark 4
France 2
Taiwan 1
Australia 1
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Trials by US State

Trials by US State for Thyrotropin Alfa
Location Trials
Maryland 5
Texas 2
Pennsylvania 1
Illinois 1
Connecticut 1
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Clinical Trial Progress for Thyrotropin Alfa

Clinical Trial Phase

Clinical Trial Phase for Thyrotropin Alfa
Clinical Trial Phase Trials
Phase 4 3
Phase 3 2
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Thyrotropin Alfa
Clinical Trial Phase Trials
Completed 15
Recruiting 2
Terminated 2
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Clinical Trial Sponsors for Thyrotropin Alfa

Sponsor Name

Sponsor Name for Thyrotropin Alfa
Sponsor Trials
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 6
National Center for Research Resources (NCRR) 2
Gustave Roussy, Cancer Campus, Grand Paris 2
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Sponsor Type

Sponsor Type for Thyrotropin Alfa
Sponsor Trials
Other 26
NIH 13
Industry 1
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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Colorcon
Chubb
Fuji
Deloitte
Express Scripts
Julphar
Argus Health
Baxter

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