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Last Updated: July 23, 2024

CLINICAL TRIALS PROFILE FOR THIOGUANINE


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All Clinical Trials for Thioguanine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed Medical Research Council Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed National Cancer Institute (NCI) Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed Eastern Cooperative Oncology Group Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00002517 ↗ Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome Completed European Organisation for Research and Treatment of Cancer - EORTC Phase 3 1993-03-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which regimen of combination chemotherapy is more effective for acute myeloid leukemia or myelodysplastic syndrome. PURPOSE: Randomized phase III trial to compare the effectiveness of different combination chemotherapy regimens in treating children who have newly diagnosed acute myeloid leukemia or myelodysplastic syndrome.
NCT00002531 ↗ Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia Unknown status Johann Wolfgang Goethe University Hospital Phase 2 1993-01-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Randomized phase II trial to study the effectiveness of various combination chemotherapy regimens in treating patients with acute lymphocytic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Thioguanine

Condition Name

Condition Name for Thioguanine
Intervention Trials
Leukemia 36
Acute Lymphoblastic Leukemia 12
Untreated Childhood Acute Lymphoblastic Leukemia 9
B Acute Lymphoblastic Leukemia 8
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Condition MeSH

Condition MeSH for Thioguanine
Intervention Trials
Leukemia 71
Precursor Cell Lymphoblastic Leukemia-Lymphoma 64
Leukemia, Lymphoid 58
Lymphoma 17
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Clinical Trial Locations for Thioguanine

Trials by Country

Trials by Country for Thioguanine
Location Trials
Canada 166
Australia 83
New Zealand 25
Switzerland 18
Puerto Rico 17
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Trials by US State

Trials by US State for Thioguanine
Location Trials
California 42
Illinois 40
New York 40
Texas 39
Michigan 38
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Clinical Trial Progress for Thioguanine

Clinical Trial Phase

Clinical Trial Phase for Thioguanine
Clinical Trial Phase Trials
Phase 4 6
Phase 3 49
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Thioguanine
Clinical Trial Phase Trials
Completed 47
Recruiting 14
Active, not recruiting 12
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Clinical Trial Sponsors for Thioguanine

Sponsor Name

Sponsor Name for Thioguanine
Sponsor Trials
National Cancer Institute (NCI) 41
Children's Oncology Group 26
Johann Wolfgang Goethe University Hospital 5
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Sponsor Type

Sponsor Type for Thioguanine
Sponsor Trials
Other 122
NIH 43
Industry 14
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