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Generated: February 23, 2019

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CLINICAL TRIALS PROFILE FOR TETRABENAZINE

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Clinical Trials for Tetrabenazine

Trial ID Title Status Sponsor Phase Summary
NCT00219804 Efficacy and Safety of Tetrabenazine in Chorea Completed Prestwick Pharmaceuticals Phase 3 The primary objective of this study was to establish the absolute reduction of chorea in participants with Huntington's disease(HD) treated with tetrabenazine or placebo
NCT00362804 Tetrabenazine for Partial Responders Completed Stanley Medical Research Institute N/A Purpose of Study: A) To improve outcome in large population of antipsychotic patients with schizophrenia or schizoaffective who are only partial responders B) To increase understanding of pharmacology and mechanisms of action underlying antipsychotic effect Hypothesis/Objectives of the Study: Tetrabenazine, through its pre-synaptic action, should augment the post-synaptic effects of an antipsychotic. Background and Rationale for the study: Preliminary evidence that other amine-depleting agents e.g., reserpine, can induce such an effect
NCT00362804 Tetrabenazine for Partial Responders Completed Centre for Addiction and Mental Health N/A Purpose of Study: A) To improve outcome in large population of antipsychotic patients with schizophrenia or schizoaffective who are only partial responders B) To increase understanding of pharmacology and mechanisms of action underlying antipsychotic effect Hypothesis/Objectives of the Study: Tetrabenazine, through its pre-synaptic action, should augment the post-synaptic effects of an antipsychotic. Background and Rationale for the study: Preliminary evidence that other amine-depleting agents e.g., reserpine, can induce such an effect
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Tetrabenazine

Condition Name

Condition Name for Tetrabenazine
Intervention Trials
Healthy 2
Schizoaffective Disorder 2
Huntington's Disease 2
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Condition MeSH

Condition MeSH for Tetrabenazine
Intervention Trials
Huntington Disease 5
Movement Disorders 2
Schizophrenia 2
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Clinical Trial Locations for Tetrabenazine

Trials by Country

Trials by Country for Tetrabenazine
Location Trials
United States 29
France 3
Canada 3
India 2
Australia 1
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Trials by US State

Trials by US State for Tetrabenazine
Location Trials
Texas 2
New York 2
Arizona 1
Arkansas 1
Colorado 1
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Clinical Trial Progress for Tetrabenazine

Clinical Trial Phase

Clinical Trial Phase for Tetrabenazine
Clinical Trial Phase Trials
Phase 4 2
Phase 3 4
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Tetrabenazine
Clinical Trial Phase Trials
Completed 5
Recruiting 5
Active, not recruiting 1
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Clinical Trial Sponsors for Tetrabenazine

Sponsor Name

Sponsor Name for Tetrabenazine
Sponsor Trials
Dr. Reddy's Laboratories Limited 2
Stanley Medical Research Institute 1
New York Medical College 1
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Sponsor Type

Sponsor Type for Tetrabenazine
Sponsor Trials
Other 12
Industry 6
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Serving hundreds of leading biopharmaceutical companies globally:

Covington
Daiichi Sankyo
Farmers Insurance
Mallinckrodt
AstraZeneca
Argus Health
Cipla
US Army
Chubb

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