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Last Updated: October 19, 2019

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CLINICAL TRIALS PROFILE FOR TESTOSTERONE ENANTHATE

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Clinical Trials for Testosterone Enanthate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00001079 A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 2 1969-12-31 To test the hypothesis that the predominant accrual of fat rather than lean body mass (LBM) that occurs during treatment of HIV-associated wasting with megestrol acetate may be improved by treatment with megestrol acetate and testosterone enanthate in combination. Body wasting is an increasingly frequent AIDS-defining condition in individuals infected with HIV. Increasing caloric intake fails to consistently restore lean tissue patients with HIV associated weight loss. Megestrol acetate has been shown to stimulate appetite and weight gain in subjects with cancer and in those with HIV associated weight loss. However, the weight gained during treatment with megestrol acetate was predominantly or exclusively fat. An important factor is the preferential increase in body fat seen in both of these studies may have been due to hypogonadism that occurs as a result of treatment with megestrol acetate, a progestational agent. Hypogonadism is associated with an increase in body fat and a decrease in LBM. Concomitant testosterone replacement should substantially increase the amount of LBM accrued during megestrol acetate therapy. This study will determine whether anabolic potential can be realized when caloric intake is increased in the absence of concomitant hypogonadism.
NCT00004771 Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease Completed Ohio State University Phase 2 1992-10-01 OBJECTIVES: I. Evaluate the effects of androgen suppression with leuprolide and androgen replacement with testosterone enanthate on muscle strength in men with Kennedy's disease or other motor neuron disease.
NCT00004771 Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease Completed National Center for Research Resources (NCRR) Phase 2 1992-10-01 OBJECTIVES: I. Evaluate the effects of androgen suppression with leuprolide and androgen replacement with testosterone enanthate on muscle strength in men with Kennedy's disease or other motor neuron disease.
NCT00260143 Testosterone and Physical Function in HIV+ Men Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Phase 2 2003-05-01 Men infected with the HIV virus (the virus that causes AIDS) often lose weight even though they may try to eat more food to gain weight. The reasons for this weight loss are not clear. Many men with HIV have low levels of testosterone in their blood. Testosterone is a hormone that is naturally produced in the bodies of both men and women and has important effects on building muscle and bone mass. The purpose of this study is to find out if providing additional testosterone to HIV infected men who have low testosterone can help them gain weight, increase their muscle mass, and feel better. The study will also help see if testosterone improves the efficiency with which your body produces and uses energy including fat. The dose of testosterone being used in this study will raise testosterone levels in the blood to higher than normal levels (2-3 times normal level).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Testosterone Enanthate

Condition Name

Condition Name for Testosterone Enanthate
Intervention Trials
Hypogonadism 6
Sarcopenia 3
Prostate Cancer 3
Aging 2
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Condition MeSH

Condition MeSH for Testosterone Enanthate
Intervention Trials
Hypogonadism 7
Prostatic Neoplasms 6
Sarcopenia 3
Muscular Atrophy 2
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Clinical Trial Locations for Testosterone Enanthate

Trials by Country

Trials by Country for Testosterone Enanthate
Location Trials
United States 64
Canada 1
Australia 1
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Trials by US State

Trials by US State for Testosterone Enanthate
Location Trials
Texas 7
Ohio 5
Massachusetts 5
Washington 4
New York 4
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Clinical Trial Progress for Testosterone Enanthate

Clinical Trial Phase

Clinical Trial Phase for Testosterone Enanthate
Clinical Trial Phase Trials
Phase 4 3
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Testosterone Enanthate
Clinical Trial Phase Trials
Completed 13
Recruiting 7
Not yet recruiting 3
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Clinical Trial Sponsors for Testosterone Enanthate

Sponsor Name

Sponsor Name for Testosterone Enanthate
Sponsor Trials
Antares Pharma Inc. 5
The University of Texas Medical Branch, Galveston 5
Sidney Kimmel Comprehensive Cancer Center 2
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Sponsor Type

Sponsor Type for Testosterone Enanthate
Sponsor Trials
Other 18
Industry 8
NIH 7
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