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Last Updated: September 27, 2020

DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR TERIPARATIDE

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All Clinical Trials for Teriparatide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000400 Alendronate and/or Parathyroid Hormone for Osteoporosis Completed National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Phase 2 1999-08-01 This study looks at the effects of two medications, alendronate and parathyroid hormone, on bone mass and on bone formation and bone breakdown in women with osteoporosis. We will randomly select postmenopausal women who have osteoporosis to receive laboratory-produced human parathyroid hormone (hPTH), or alendronate, or both for 2.5 years. Study participants will return to the study center periodically to have their bone mass measured and to give blood and urine samples for tests of bone formation and breakdown and for other laboratory tests. Those who complete the study are eligible for one or two 12 month extension studies.
NCT00000400 Alendronate and/or Parathyroid Hormone for Osteoporosis Completed Massachusetts General Hospital Phase 2 1999-08-01 This study looks at the effects of two medications, alendronate and parathyroid hormone, on bone mass and on bone formation and bone breakdown in women with osteoporosis. We will randomly select postmenopausal women who have osteoporosis to receive laboratory-produced human parathyroid hormone (hPTH), or alendronate, or both for 2.5 years. Study participants will return to the study center periodically to have their bone mass measured and to give blood and urine samples for tests of bone formation and breakdown and for other laboratory tests. Those who complete the study are eligible for one or two 12 month extension studies.
NCT00005006 Parathyroid Hormone (PTH) With Alendronate for Osteoporosis Completed National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Phase 2 1987-09-01 This study investigates the effectiveness of parathyroid hormone (PTH) in combination with alendronate, a standard treatment for osteoporosis that blocks or reduces bone loss. We are using alendronate because it may help protect patients against any possible harmful effects of PTH in cortical bone such as the long bones or hip. We are testing two different treatment schedules of PTH-one in which we give PTH daily and one in which we give PTH for 3 out of every 6 months in a cyclical fashion. The entire study is 21 months long; the active treatment period is 18 months with a 6-month followup period. The main effects we will look for in this study are changes in body chemicals that are signs of bone formation or bone breakdown, and changes in bone density throughout the skeleton. We will randomly assign all study participants, who are women aged 50 and over, to either stay on alendronate alone, receive daily continuous PTH plus alendronate, or receive daily PTH for 3 months out of every 6 for a total of three separate 3-month cycles of PTH plus daily alendronate.
NCT00005006 Parathyroid Hormone (PTH) With Alendronate for Osteoporosis Completed Helen Hayes Hospital Phase 2 1987-09-01 This study investigates the effectiveness of parathyroid hormone (PTH) in combination with alendronate, a standard treatment for osteoporosis that blocks or reduces bone loss. We are using alendronate because it may help protect patients against any possible harmful effects of PTH in cortical bone such as the long bones or hip. We are testing two different treatment schedules of PTH-one in which we give PTH daily and one in which we give PTH for 3 out of every 6 months in a cyclical fashion. The entire study is 21 months long; the active treatment period is 18 months with a 6-month followup period. The main effects we will look for in this study are changes in body chemicals that are signs of bone formation or bone breakdown, and changes in bone density throughout the skeleton. We will randomly assign all study participants, who are women aged 50 and over, to either stay on alendronate alone, receive daily continuous PTH plus alendronate, or receive daily PTH for 3 months out of every 6 for a total of three separate 3-month cycles of PTH plus daily alendronate.
NCT00035256 Sequential Use of Teriparatide and Raloxifene HCl in the Treatment of Postmenopausal Women With Osteoporosis Completed Eli Lilly and Company Phase 4 2001-10-01 The purpose of this study is to determine whether the increase in spine bone mineral density that has been generally observed in previous clinical studies involving the study drug can be maintained or even increased if followed with raloxifene HCl. All qualifying study participants will receive the study drug followed by treatment with raloxifene HCl or placebo. All study participants will receive raloxifene HCl in the third phase of the study.
NCT00046137 Combined Use of Teriparatide and Raloxifene in Postmenopausal Women With Osteoporosis Completed Eli Lilly and Company Phase 3 1969-12-31 The purpose of this study is to compare treatment with both teriparatide and raloxifene with teriparatide alone. The study will evaluate any side effects that may be associated with the two drugs and may help to determine whether teriparatide and raloxifene together can help patients with osteoporosis more than teriparatide alone.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Teriparatide

Condition Name

Condition Name for Teriparatide
Intervention Trials
Osteoporosis 64
Osteoporosis, Postmenopausal 13
Postmenopausal Osteoporosis 11
Osteoporosis, Post-Menopausal 5
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Condition MeSH

Condition MeSH for Teriparatide
Intervention Trials
Osteoporosis 97
Osteoporosis, Postmenopausal 32
Fractures, Bone 16
Hip Fractures 6
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Clinical Trial Locations for Teriparatide

Trials by Country

Trials by Country for Teriparatide
Location Trials
United States 235
Canada 38
Denmark 13
Spain 12
Germany 12
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Trials by US State

Trials by US State for Teriparatide
Location Trials
New York 18
Nebraska 12
California 12
Massachusetts 12
Georgia 12
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Clinical Trial Progress for Teriparatide

Clinical Trial Phase

Clinical Trial Phase for Teriparatide
Clinical Trial Phase Trials
Phase 4 42
Phase 3 29
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Teriparatide
Clinical Trial Phase Trials
Completed 74
Recruiting 15
Active, not recruiting 13
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Clinical Trial Sponsors for Teriparatide

Sponsor Name

Sponsor Name for Teriparatide
Sponsor Trials
Eli Lilly and Company 50
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 8
Massachusetts General Hospital 7
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Sponsor Type

Sponsor Type for Teriparatide
Sponsor Trials
Other 114
Industry 80
NIH 18
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Serving leading biopharmaceutical companies globally:

Medtronic
McKinsey
Mallinckrodt
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Boehringer Ingelheim

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