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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR TEPADINA


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All Clinical Trials for Tepadina

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00554788 ↗ Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Active, not recruiting National Cancer Institute (NCI) Phase 3 2008-02-04 This phase III trial is studying the side effects and how well giving combination chemotherapy together with autologous stem cell transplant and/or radiation therapy works in treating young patients with extraocular retinoblastoma. Giving chemotherapy before an autologous stem cell transplant stops the growth of tumor cells by stopping them from dividing or killing them. After treatment, stem cells are collected from the patient?s blood and/or bone marrow and stored. More chemotherapy is given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. Radiation therapy uses high energy x-rays to kill tumor cells. Giving radiation therapy after combination chemotherapy and/or autologous stem cell transplant may kill any remaining tumor cells.
NCT00554788 ↗ Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Active, not recruiting Children's Oncology Group Phase 3 2008-02-04 This phase III trial is studying the side effects and how well giving combination chemotherapy together with autologous stem cell transplant and/or radiation therapy works in treating young patients with extraocular retinoblastoma. Giving chemotherapy before an autologous stem cell transplant stops the growth of tumor cells by stopping them from dividing or killing them. After treatment, stem cells are collected from the patient?s blood and/or bone marrow and stored. More chemotherapy is given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. Radiation therapy uses high energy x-rays to kill tumor cells. Giving radiation therapy after combination chemotherapy and/or autologous stem cell transplant may kill any remaining tumor cells.
NCT00567567 ↗ Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma Active, not recruiting National Cancer Institute (NCI) Phase 3 2007-11-05 This randomized phase III trial compares two different high-dose chemotherapy regimens followed by a stem cell transplant in treating younger patients with high-risk neuroblastoma. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving these treatments before a peripheral blood stem cell transplant helps kill any tumor cells that are in the body and helps make room in the patient?s bone marrow for new blood-forming cells (stem cells) to grow. After treatment, stem cells are collected from the patient's blood and stored. High-dose chemotherapy and radiation therapy is then given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the high- chemotherapy. It is not yet known which regimen of high-dose chemotherapy is more effective for patients with high-risk neuroblastoma undergoing a peripheral blood stem cell transplant.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Tepadina

Condition Name

Condition Name for Tepadina
Intervention Trials
Acute Myeloid Leukemia 7
Acute Lymphoblastic Leukemia 6
Myelodysplastic Syndrome 5
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Condition MeSH

Condition MeSH for Tepadina
Intervention Trials
Leukemia 12
Preleukemia 11
Myelodysplastic Syndromes 11
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Clinical Trial Locations for Tepadina

Trials by Country

Trials by Country for Tepadina
Location Trials
United States 222
Canada 17
Australia 9
New Zealand 2
Italy 2
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Trials by US State

Trials by US State for Tepadina
Location Trials
Washington 11
Texas 11
Pennsylvania 10
New York 10
California 10
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Clinical Trial Progress for Tepadina

Clinical Trial Phase

Clinical Trial Phase for Tepadina
Clinical Trial Phase Trials
Phase 3 6
Phase 2 18
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Tepadina
Clinical Trial Phase Trials
Recruiting 11
Active, not recruiting 7
Not yet recruiting 4
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Clinical Trial Sponsors for Tepadina

Sponsor Name

Sponsor Name for Tepadina
Sponsor Trials
National Cancer Institute (NCI) 17
Fred Hutchinson Cancer Research Center 8
Children's Oncology Group 6
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Sponsor Type

Sponsor Type for Tepadina
Sponsor Trials
Other 29
NIH 22
Industry 5
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