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Last Updated: December 12, 2024

CLINICAL TRIALS PROFILE FOR TENOFOVIR ALAFENAMIDE


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All Clinical Trials for Tenofovir Alafenamide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00036634 ↗ A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients Completed Gilead Sciences Phase 1/Phase 2 2002-03-01 This study evaluated two doses of tenofovir alafenamide versus tenofovir disoproxil fumarate (tenofovir DF).
NCT01497899 ↗ Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive Adults Completed Gilead Sciences Phase 2 2011-12-28 The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (Genvoya®; E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (Stribild®; E/C/F/TDF) FDC in HIV-1 infected, antiretroviral treatment-naive adults.
NCT01565850 ↗ D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults Completed Gilead Sciences Phase 2 2012-04-01 This study is to evaluate the safety and efficacy darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) fixed dose combination (FDC) tablet versus darunavir (DRV)+cobicistat (COBI)+emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in HIV-1 infected, antiretroviral treatment-naive adults as determined by the achievement of HIV-1 RNA < 50 copies/mL at Week 24.
NCT01780506 ↗ Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults Completed Gilead Sciences Phase 3 2012-12-26 The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (E/C/F/TDF) FDC in HIV-1 positive, antiretroviral treatment-naive adults.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Tenofovir Alafenamide

Condition Name

Condition Name for Tenofovir Alafenamide
Intervention Trials
HIV Infections 36
Hiv 29
HIV-1 Infection 24
HIV-1-infection 22
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Condition MeSH

Condition MeSH for Tenofovir Alafenamide
Intervention Trials
HIV Infections 54
Hepatitis B 54
Hepatitis 48
Hepatitis B, Chronic 35
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Clinical Trial Locations for Tenofovir Alafenamide

Trials by Country

Trials by Country for Tenofovir Alafenamide
Location Trials
United States 828
Canada 99
China 83
France 67
Spain 55
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Trials by US State

Trials by US State for Tenofovir Alafenamide
Location Trials
California 61
Texas 52
Florida 51
Georgia 43
New York 41
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Clinical Trial Progress for Tenofovir Alafenamide

Clinical Trial Phase

Clinical Trial Phase for Tenofovir Alafenamide
Clinical Trial Phase Trials
Phase 4 74
Phase 3 62
Phase 2/Phase 3 6
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Clinical Trial Status

Clinical Trial Status for Tenofovir Alafenamide
Clinical Trial Phase Trials
Completed 71
Recruiting 67
Not yet recruiting 34
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Clinical Trial Sponsors for Tenofovir Alafenamide

Sponsor Name

Sponsor Name for Tenofovir Alafenamide
Sponsor Trials
Gilead Sciences 85
National Institute of Allergy and Infectious Diseases (NIAID) 7
ViiV Healthcare 7
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Sponsor Type

Sponsor Type for Tenofovir Alafenamide
Sponsor Trials
Other 267
Industry 140
NIH 9
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