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Generated: December 15, 2018

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CLINICAL TRIALS PROFILE FOR TELMISARTAN AND AMLODIPINE

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Clinical Trials for Telmisartan And Amlodipine

Trial ID Title Status Sponsor Phase Summary
NCT00240474 A Comparison of Telmisartan + Hydrochlorothiazide With Amlodipine + Hydrochlorothiazide in the Control of Blood Pressure in Older Patients With Predominantly Systolic Hypertension (ATHOS Study) Completed Boehringer Ingelheim Phase 4 The primary objective of this study was test non-inferiority of telmisartan 80 mg + hydrochlorothiazide (HCTZ) 12.5 mg in comparison to amlodipine 10 mg + HCTZ 12.5 mg in reducing ambulatory systolic blood pressure (SBP) in the last 6 hours of the 24-hour dosing interval (determined by ambulatory blood pressure monitoring: ABPM) in elderly patients with predominantly systolic hypertension.
NCT00242814 Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities Completed Boehringer Ingelheim Phase 4 The objective of the study is to compare PPAR activities (increase of adiponectin level) between MICARDIS and amlodipine after 6 weeks of treatment in hypertensive patients with metabolic syndrome. Moreover, this study will compare serum level of inflammatory markers of the metabolic syndrome after 6 weeks of treatment. An ancillary study performed in one center will assess adipocyte differentiation (PPAR gamma stimulation) in 30 subjects (15 per arm).
NCT00281580 Telmisartan (Micardis) and Amlodipine (Norvasc) - Factorial Design Study for the Treatment of Hypertension Completed Boehringer Ingelheim Phase 3 To demonstrate that Micardis and Norvasc when used together are more effective at lowering blood pre ssure.
NCT00509470 Evaluation of Effect of Combination With Telmisartan and Hydrochlorothiazide in Hypertensives Uncontrolled on Amlodipine Completed Tokyo University Phase 4 The purpose of this study is to compare depressor effect and safety between combination therapy with telmisartan plus low-dose hydrochlorothiazide and amlodipine in hypertensive patients.
NCT00538486 A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients Completed Third Military Medical University Phase 4 The epidemic of obesity is associated with a considerable rise in the incidence of the metabolic syndrome, type 2 diabetes mellitus, and hypertension. Insulin resistance plays an important role in the pathogenesis of obesity related hypertension. These patients are at high risk to suffer from cardiovascular events. However, current guidelines for treatment of hypertension do not provide specific recommendation for the pharmacotherapy of obese hypertensive patients due to lack of prospective randomized intervention studies in non-diabetic obese hypertensive patients. Aside from their antihypertensive effects, angiotensin II receptor blockers (ARB) were shown to improve insulin sensitivity. Furthermore, metformin is commonly used to treat the obese type 2 diabetes mellitus. Metformin can also lower body weight and increase insulin sensitivity. In a prospective, double-blind, double-dummy, randomized, parallel-group study, we will evaluate the effects of ARB (telmisartan and candesartan) or amlodipine combination with metformin on weight gain, visceral fat, and metabolic parameters in obese hypertensive patients without diabetes mellitus compared with obese hypertensives on ARB or amlodipine treatment alone. This study will help to develop future comprehensive treatment strategies and guidelines for obesity related hypertension.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Telmisartan And Amlodipine

Condition Name

Condition Name for Telmisartan And Amlodipine
Intervention Trials
Hypertension 46
Healthy 14
Essential Hypertension 7
Hyperlipidemia 6
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Condition MeSH

Condition MeSH for Telmisartan And Amlodipine
Intervention Trials
Hypertension 40
Hyperlipidemias 8
Hyperlipoproteinemias 2
Diabetes Mellitus 2
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Clinical Trial Locations for Telmisartan And Amlodipine

Trials by Country

Trials by Country for Telmisartan And Amlodipine
Location Trials
Korea, Republic of 59
United States 55
Japan 12
Canada 9
China 7
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Trials by US State

Trials by US State for Telmisartan And Amlodipine
Location Trials
Texas 3
Oklahoma 3
Georgia 3
Florida 3
California 3
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Clinical Trial Progress for Telmisartan And Amlodipine

Clinical Trial Phase

Clinical Trial Phase for Telmisartan And Amlodipine
Clinical Trial Phase Trials
Phase 4 15
Phase 3 25
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Telmisartan And Amlodipine
Clinical Trial Phase Trials
Completed 63
Recruiting 5
Unknown status 4
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Clinical Trial Sponsors for Telmisartan And Amlodipine

Sponsor Name

Sponsor Name for Telmisartan And Amlodipine
Sponsor Trials
Boehringer Ingelheim 36
Chong Kun Dang Pharmaceutical 17
Yuhan Corporation 6
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Sponsor Type

Sponsor Type for Telmisartan And Amlodipine
Sponsor Trials
Industry 67
Other 13
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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
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US Army
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Covington
Mallinckrodt
McKinsey
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Farmers Insurance

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