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Generated: December 12, 2018

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CLINICAL TRIALS PROFILE FOR TAMOXIFEN CITRATE

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Clinical Trials for Tamoxifen Citrate

Trial ID Title Status Sponsor Phase Summary
NCT00003199 Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer Completed National Cancer Institute (NCI) Phase 2 This phase II trial studies how well giving combination chemotherapy and peripheral blood stem cell transplant followed by aldesleukin and sargramostim works in treating patients with inflammatory stage IIIB or metastatic stage IV breast cancer. Drugs used in chemotherapy, such as busulfan, melphalan, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. A peripheral stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy. This may allow more chemotherapy to be given so that more tumor cells are killed. Aldesleukin may stimulate the white blood cells to kill breast cancer cells. Giving aldesleukin together with sargramostim may kill more tumor cells
NCT00003199 Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer Completed Fred Hutchinson Cancer Research Center Phase 2 This phase II trial studies how well giving combination chemotherapy and peripheral blood stem cell transplant followed by aldesleukin and sargramostim works in treating patients with inflammatory stage IIIB or metastatic stage IV breast cancer. Drugs used in chemotherapy, such as busulfan, melphalan, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. A peripheral stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy. This may allow more chemotherapy to be given so that more tumor cells are killed. Aldesleukin may stimulate the white blood cells to kill breast cancer cells. Giving aldesleukin together with sargramostim may kill more tumor cells
NCT00066690 Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer Active, not recruiting Breast International Group Phase 3 RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or exemestane may fight breast cancer by reducing the production of estrogen. It is not yet known whether suppression of ovarian function plus either tamoxifen or exemestane is more effective than tamoxifen alone in preventing the recurrence of hormone-responsive breast cancer. PURPOSE: This randomized phase III trial studies ovarian suppression with either tamoxifen or exemestane to see how well they work compared to tamoxifen alone in treating premenopausal women who have undergone surgery for hormone-responsive breast cancer.
NCT00066690 Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer Active, not recruiting Cancer and Leukemia Group B Phase 3 RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or exemestane may fight breast cancer by reducing the production of estrogen. It is not yet known whether suppression of ovarian function plus either tamoxifen or exemestane is more effective than tamoxifen alone in preventing the recurrence of hormone-responsive breast cancer. PURPOSE: This randomized phase III trial studies ovarian suppression with either tamoxifen or exemestane to see how well they work compared to tamoxifen alone in treating premenopausal women who have undergone surgery for hormone-responsive breast cancer.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Tamoxifen Citrate

Condition Name

Condition Name for Tamoxifen Citrate
Intervention Trials
Breast Cancer 21
Stage IIIB Breast Cancer 5
Stage IV Breast Cancer 5
Estrogen Receptor Positive 4
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Condition MeSH

Condition MeSH for Tamoxifen Citrate
Intervention Trials
Breast Neoplasms 32
Carcinoma 5
Carcinoma in Situ 4
Carcinoma, Intraductal, Noninfiltrating 3
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Clinical Trial Locations for Tamoxifen Citrate

Trials by Country

Trials by Country for Tamoxifen Citrate
Location Trials
United States 430
Canada 30
China 20
United Kingdom 14
Ireland 8
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Trials by US State

Trials by US State for Tamoxifen Citrate
Location Trials
California 14
North Carolina 13
Minnesota 13
Michigan 12
Illinois 12
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Clinical Trial Progress for Tamoxifen Citrate

Clinical Trial Phase

Clinical Trial Phase for Tamoxifen Citrate
Clinical Trial Phase Trials
Phase 4 4
Phase 3 15
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Tamoxifen Citrate
Clinical Trial Phase Trials
Unknown status 14
Active, not recruiting 12
Completed 9
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Clinical Trial Sponsors for Tamoxifen Citrate

Sponsor Name

Sponsor Name for Tamoxifen Citrate
Sponsor Trials
National Cancer Institute (NCI) 21
Mayo Clinic 3
Novartis 3
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Sponsor Type

Sponsor Type for Tamoxifen Citrate
Sponsor Trials
Other 86
NIH 21
Industry 6
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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Argus Health
Johnson and Johnson
Citi
Healthtrust
McKinsey
Cipla
Merck
Medtronic

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